S-Adenosyl-L-Methionine Cycle

Proteins (4)

Protein	Synonyms	Taxonomy
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	MTA/SAH nucleosidase; MTAN; EC 3.2.2.9; 5'-deoxyadenosine nucleosidase; DOA nucleosidase; dAdo nucleosidase; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidas	Escherichia coli K-12
S-ribosylhomocysteine lyase	EC 4.4.1.21; AI-2 synthesis protein; Autoinducer-2 production protein LuxS	Escherichia coli K-12
S-adenosylmethionine synthase	AdoMet synthase; EC 2.5.1.6; MAT; Methionine adenosyltransferase	Escherichia coli K-12
Methionine synthase	EC 2.1.1.13; 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12-dependent; MS	Escherichia coli K-12

Compound	Description
hydronium ion
Orthophosphate
adenine	A purine base and a fundamental unit of ADENINE NUCLEOTIDES.
betaine	A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)
Adenosine Triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
methionine	A sulfur-containing essential L-amino acid that is important in many body functions.
Water	A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
dimethylglycine	metabolic product of calcium pangamate; mutagen when mixed with nitrite; RN given refers to parent cpd
s-adenosylmethionine	Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
pyrophosphate