Pathways > S-Adenosyl-L-Methionine Biosynthesis
Page last updated: 2024-10-06
S-Adenosyl-L-Methionine Biosynthesis
Proteins (8)
| Protein | Synonyms | Taxonomy |
|---|
| 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | MTA/SAH nucleosidase; MTAN; EC 3.2.2.9; 5'-deoxyadenosine nucleosidase; DOA nucleosidase; dAdo nucleosidase; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidas | Escherichia coli K-12 |
| Spermidine N(1)-acetyltransferase | SAT; EC 2.3.1.57; Spermidine/spermine N(1)-acetyltransferase; SSAT | Escherichia coli K-12 |
| S-adenosylmethionine decarboxylase proenzyme | AdoMetDC; SAMDC; EC 4.1.1.50 | Escherichia coli K-12 |
| S-adenosylmethionine synthase | AdoMet synthase; EC 2.5.1.6; MAT; Methionine adenosyltransferase | Escherichia coli K-12 |
| Polyamine aminopropyltransferase | Cadaverine aminopropyltransferase; 2.5.1.-; Putrescine aminopropyltransferase; PAPT; Spermidine aminopropyltransferase; 2.5.1.79; Spermidine synthase; SPDS; SPDSY; 2.5.1.16; Spermine synthase; 2.5.1.22; Thermospermine synthase | Escherichia coli K-12 |
| D-methionine-binding lipoprotein MetQ | | Escherichia coli K-12 |
| Methionine import ATP-binding protein MetN | EC 7.4.2.11 | Escherichia coli K-12 |
| D-methionine transport system permease protein MetI | | Escherichia coli K-12 |
Compounds (16)
| Compound | Description |
|---|
| hydronium ion | |
| Orthophosphate | |
| adenine | A purine base and a fundamental unit of ADENINE NUCLEOTIDES. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| methionine | A sulfur-containing essential L-amino acid that is important in many body functions. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Coenzyme A | |
| spermidine | A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine. |
| n(8)-acetylspermidine | |
| s-adenosyl-3-methylthiopropylamine | decarboxylated S-adenosylmethionine |
| putrescine | A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| pyrophosphate | |