Page last updated: 2024-10-06

Roles of ceramides in development of insulin resistance

Proteins (19)

ProteinSynonymsTaxonomy
Insulin receptor substrate 1IRS-1Homo sapiens (human)
Sphingomyelin phosphodiesterase 3EC 3.1.4.12; Neutral sphingomyelinase 2; nSMase-2; nSMase2; Neutral sphingomyelinase IIHomo sapiens (human)
Insulin receptorIR; EC 2.7.10.1Homo sapiens (human)
Protein kinase C zeta typeEC 2.7.11.13; nPKC-zetaHomo sapiens (human)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoformPP2A-alpha; EC 3.1.3.16; Replication protein C; RP-CHomo sapiens (human)
Serine/threonine-protein kinase/endoribonuclease IRE1Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1aHomo sapiens (human)
Ribosomal protein S6 kinase beta-1S6K-beta-1; S6K1; EC 2.7.11.1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KAHomo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
Long-chain-fatty-acid--CoA ligase 1EC 6.2.1.3; Acyl-CoA synthetase 1; ACS1; Arachidonate--CoA ligase; 6.2.1.15; Long-chain acyl-CoA synthetase 1; LACS 1; Long-chain acyl-CoA synthetase 2; LACS 2; Long-chain fatty acid-CoA ligase 2; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; Phytanate-Homo sapiens (human)
Platelet glycoprotein 4Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptorHomo sapiens (human)
Tumor necrosis factor receptor superfamily member 1ATumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60Homo sapiens (human)
InsulinHomo sapiens (human)
Tumor necrosis factorCachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-aHomo sapiens (human)
Solute carrier family 2, facilitated glucose transporter member 4Glucose transporter type 4, insulin-responsive; GLUT-4Homo sapiens (human)
Carnitine O-palmitoyltransferase 1, muscle isoformCPT1-M; EC 2.3.1.21; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B; Carnitine palmitoyltransferase I-like proteinHomo sapiens (human)
5'-AMP-activated protein kinase subunit gamma-3AMPK gamma3; AMPK subunit gamma-3Homo sapiens (human)
TNF receptor-associated factor 1Epstein-Barr virus-induced protein 6Homo sapiens (human)
Transcription factor MafAPancreatic beta-cell-specific transcriptional activator; RIPE3b1 factor; V-maf musculoaponeurotic fibrosarcoma oncogene homolog AHomo sapiens (human)
Insulin receptor substrate 2IRS-2Homo sapiens (human)

Compounds (4)

CompoundDescription
oleic acidAn unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)
palmitic acidA common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
SamariumAn element of the rare earth family of metals. It has the atomic symbol Sm, atomic number 62, and atomic weight 150.36. The oxide is used in the control rods of some nuclear reactors.
palmitoyl coenzyme aA fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.