Page last updated: 2024-10-06

Resistance of ERBB2 KD mutants to sapitinib

Proteins (4)

ProteinSynonymsTaxonomy
Receptor tyrosine-protein kinase erbB-2EC 2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2Homo sapiens (human)
Heat shock protein HSP 90-alphaEC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38Homo sapiens (human)
Hsp90 co-chaperone Cdc37Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37Homo sapiens (human)
ErbinDensin-180-like protein; Erbb2-interacting protein; Protein LAP2Homo sapiens (human)

Compounds (1)

CompoundDescription
azd 8931an EGFR inhibitor with antineoplastic activity; structure in first source