| Protein | Synonyms | Taxonomy |
|---|---|---|
| Heat shock protein HSP 90-alpha | EC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38 | Homo sapiens (human) |
| Hsp90 co-chaperone Cdc37 | Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37 | Homo sapiens (human) |
| Erbin | Densin-180-like protein; Erbb2-interacting protein; Protein LAP2 | Homo sapiens (human) |
| Compound | Description |
|---|---|
| lapatinib | A quinazoline derivative that inhibits EPIDERMAL GROWTH FACTOR RECEPTOR and HER2 (RECEPTOR, ERBB-2) tyrosine kinases. It is used for the treatment of advanced or metastatic breast cancer, where tumors overexpress HER2. |