Page last updated: 2024-10-06

Regulation of TP53 Activity through Methylation

Proteins (15)

ProteinSynonymsTaxonomy
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
Protein Mdm4Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4Homo sapiens (human)
Serine/threonine-protein kinase Chk2EC 2.7.11.1; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2Homo sapiens (human)
E3 ubiquitin-protein ligase Mdm2EC 2.3.2.27; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; RING-type E3 ubiquitin transferase Mdm2; p53-binding protein Mdm2Homo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Histone-lysine N-methyltransferase EHMT2EC 2.1.1.-; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Lysine N-methyltransferase 1C; Protein G9aHomo sapiens (human)
Histone-lysine N-methyltransferase EHMT1EC 2.1.1.-; Euchromatic histone-lysine N-methyltransferase 1; Eu-HMTase1; G9a-like protein 1; GLP; GLP1; Histone H3-K9 methyltransferase 5; H3-K9-HMTase 5; Lysine N-methyltransferase 1DHomo sapiens (human)
Protein arginine N-methyltransferase 5PRMT5; EC 2.1.1.320; 72 kDa ICln-binding protein; Histone-arginine N-methyltransferase PRMT5; Jak-binding protein 1; Shk1 kinase-binding protein 1 homolog; SKB1 homolog; SKB1HsHomo sapiens (human)
Serine-protein kinase ATMEC 2.7.11.1; Ataxia telangiectasia mutated; A-T mutatedHomo sapiens (human)
N-lysine methyltransferase SMYD2EC 2.1.1.-; HSKM-B; Histone methyltransferase SMYD2; 2.1.1.354; Lysine N-methyltransferase 3C; SET and MYND domain-containing protein 2Homo sapiens (human)
Lethal(3)malignant brain tumor-like protein 1H-l(3)mbt; H-l(3)mbt protein; L(3)mbt-like; L(3)mbt protein homolog; L3MBTL1Homo sapiens (human)
Tetratricopeptide repeat protein 5TPR repeat protein 5; Stress-responsive activator of p300; StrapHomo sapiens (human)
N-lysine methyltransferase KMT5AEC 2.1.1.-; H4-K20-HMTase KMT5A; Histone-lysine N-methyltransferase KMT5A; 2.1.1.361; Lysine N-methyltransferase 5A; Lysine-specific methylase 5A; PR/SET domain-containing protein 07; PR-Set7; PR/SET07; SET domain-containing protein 8Homo sapiens (human)
Junction-mediating and -regulatory proteinHomo sapiens (human)
SET domain-containing protein 9EC 2.1.1.-Homo sapiens (human)

Compounds (3)

CompoundDescription
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)