Pathways > Regulation of HSF1-mediated heat shock response
Page last updated: 2024-10-06

Regulation of HSF1-mediated heat shock response

Proteins (54)

ProteinSynonymsTaxonomy
Heat shock 70 kDa protein 4HSP70RY; Heat shock 70-related protein APG-2Homo sapiens (human)
Stress-70 protein, mitochondrial75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74; PBP74Homo sapiens (human)
Heat shock 70 kDa protein 14HSP70-like protein 1; Heat shock protein HSP60Homo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
Mitogen-activated protein kinase 1MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2Homo sapiens (human)
MAP kinase-activated protein kinase 2MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2; EC 2.7.11.1Homo sapiens (human)
Glycogen synthase kinase-3 betaGSK-3 beta; EC 2.7.11.26; Serine/threonine-protein kinase GSK3B; 2.7.11.1Homo sapiens (human)
NAD-dependent protein deacetylase sirtuin-1hSIRT1; EC 2.3.1.286; NAD-dependent protein deacylase sirtuin-1; 2.3.1.-; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2Homo sapiens (human)
Replication protein A 70 kDa DNA-binding subunitRP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding proteinHomo sapiens (human)
Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1; HSP70-1; HSP70.1Homo sapiens (human)
Heat shock cognate 71 kDa proteinEC 3.6.4.10; Heat shock 70 kDa protein 8; Lipopolysaccharide-associated protein 1; LAP-1; LPS-associated protein 1Homo sapiens (human)
Heat shock factor protein 1HSF 1; Heat shock transcription factor 1; HSTF 1Homo sapiens (human)
Endoplasmic reticulum chaperone BiPEC 3.6.4.10; 78 kDa glucose-regulated protein; GRP-78; Binding-immunoglobulin protein; BiP; Heat shock protein 70 family protein 5; HSP70 family protein 5; Heat shock protein family A member 5; Immunoglobulin heavy chain-binding proteinHomo sapiens (human)
Heat shock-related 70 kDa protein 2Heat shock 70 kDa protein 2Homo sapiens (human)
E3 SUMO-protein ligase RanBP2EC 2.3.2.-; 358 kDa nucleoporin; Nuclear pore complex protein Nup358; Nucleoporin Nup358; Ran-binding protein 2; RanBP2; p270Homo sapiens (human)
Heat shock 70 kDa protein 6Heat shock 70 kDa protein B'Homo sapiens (human)
14-3-3 protein epsilon14-3-3EHomo sapiens (human)
Nuclear pore complex protein Nup155155 kDa nucleoporin; Nucleoporin Nup155Homo sapiens (human)
Heat shock 70 kDa protein 1B Heat shock 70 kDa protein 2; HSP70-2; HSP70.2Homo sapiens (human)
Hsc70-interacting proteinHip; Aging-associated protein 2; Progesterone receptor-associated p48 protein; Protein FAM10A1; Putative tumor suppressor ST13; Renal carcinoma antigen NY-REN-33; Suppression of tumorigenicity 13 proteinHomo sapiens (human)
Nuclear pore complex protein Nup8888 kDa nucleoporin; Nucleoporin Nup88Homo sapiens (human)
Cell cycle and apoptosis regulator protein 2Cell division cycle and apoptosis regulator protein 2; DBIRD complex subunit KIAA1967; Deleted in breast cancer gene 1 protein; DBC-1; DBC.1; NET35; p30 DBCHomo sapiens (human)
mRNA export factorRae1 protein homolog; mRNA-associated protein mrnp 41Homo sapiens (human)
Nuclear pore membrane glycoprotein 210Nuclear pore protein gp210; Nuclear envelope pore membrane protein POM 210; POM210; Nucleoporin Nup210; Pore membrane protein of 210 kDaHomo sapiens (human)
Nucleoporin NUP42NLP-1; NUP42 homolog; Nucleoporin hCG1; Nucleoporin-42; Nucleoporin-like protein 2Homo sapiens (human)
Heat shock 70 kDa protein 12AHomo sapiens (human)
Heat shock 70 kDa protein 4LHeat shock 70-related protein APG-1; Osmotic stress protein 94Homo sapiens (human)
Nucleoprotein TPRMegator; NPC-associated intranuclear protein; Translocated promoter region proteinHomo sapiens (human)
Replication protein A 32 kDa subunitRP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34Homo sapiens (human)
Heat shock 70 kDa protein 1-likeHeat shock 70 kDa protein 1L; Heat shock 70 kDa protein 1-Hom; HSP70-HomHomo sapiens (human)
Replication protein A 14 kDa subunitRP-A p14; Replication factor A protein 3; RF-A protein 3Homo sapiens (human)
Nuclear pore complex protein Nup214214 kDa nucleoporin; Nucleoporin Nup214; Protein CANHomo sapiens (human)
Nuclear pore glycoprotein p6262 kDa nucleoporin; Nucleoporin Nup62Homo sapiens (human)
Heat shock 70 kDa protein 13Microsomal stress-70 protein ATPase core; Stress-70 protein chaperone microsome-associated 60 kDa proteinHomo sapiens (human)
Putative heat shock 70 kDa protein 7Heat shock 70 kDa protein BHomo sapiens (human)
Nuclear pore complex protein Nup153153 kDa nucleoporin; Nucleoporin Nup153Homo sapiens (human)
Protein SEC13 homologGATOR complex protein SEC13; SEC13-like protein 1; SEC13-related proteinHomo sapiens (human)
Nuclear pore complex protein Nup107107 kDa nucleoporin; Nucleoporin Nup107Homo sapiens (human)
Nuclear pore complex protein Nup160160 kDa nucleoporin; Nucleoporin Nup160Homo sapiens (human)
Protein HikeshiHomo sapiens (human)
Nucleoporin NUP188hNup188Homo sapiens (human)
Nucleoporin p5454 kDa nucleoporinHomo sapiens (human)
Active regulator of SIRT140S ribosomal protein S19-binding protein 1; RPS19-binding protein 1; S19BPHomo sapiens (human)
Nuclear pore complex protein Nup9393 kDa nucleoporin; Nucleoporin Nup93Homo sapiens (human)
Nucleoporin Nup43Nup107-160 subcomplex subunit Nup43; p42Homo sapiens (human)
Nucleoporin Nup37p37; Nup107-160 subcomplex subunit Nup37Homo sapiens (human)
Nucleoporin NUP3535 kDa nucleoporin; Mitotic phosphoprotein 44; MP-44; Nuclear pore complex protein Nup53; Nucleoporin NUP53Homo sapiens (human)
Nuclear pore complex protein Nup133133 kDa nucleoporin; Nucleoporin Nup133Homo sapiens (human)
Nuclear pore complex protein Nup205205 kDa nucleoporin; Nucleoporin Nup205Homo sapiens (human)
Heat shock 70 kDa protein 12BHomo sapiens (human)
Nucleoporin NDC1hNDC1; Transmembrane protein 48Homo sapiens (human)
Nuclear pore complex protein Nup8585 kDa nucleoporin; FROUNT; Nucleoporin Nup75; Nucleoporin Nup85; Pericentrin-1Homo sapiens (human)
AladinAdracalinHomo sapiens (human)
Nuclear pore complex protein Nup5050 kDa nucleoporin; Nuclear pore-associated protein 60 kDa-like; Nucleoporin Nup50Homo sapiens (human)

Compounds (7)

CompoundDescription
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
niacinamideAn important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
o-acetyl-adp-riboseAn acetyl ester of ADENOSINE DIPHOSPHATE RIBOSE formed during NAD-dependent deacetylation of proteins by SIRTUINS. The acetate group resides on the ribose ring where nicotinamide was cleaved from NAD during the reaction. Several isomers of O-acetyl-ADP-ribose have been isolated from the reaction.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.