Page last updated: 2024-10-06

RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

Proteins (22)

ProteinSynonymsTaxonomy
Histone-lysine N-methyltransferase 2DLysine N-methyltransferase 2D; EC 2.1.1.354; ALL1-related protein; Myeloid/lymphoid or mixed-lineage leukemia protein 2Homo sapiens (human)
Thrombospondin-1Glycoprotein GHomo sapiens (human)
Runt-related transcription factor 1Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor Homo sapiens (human)
Core-binding factor subunit betaCBF-beta; Polyomavirus enhancer-binding protein 2 beta subunit; PEA2-beta; PEBP2-beta; SL3-3 enhancer factor 1 subunit beta; SL3/AKV core-binding factor beta subunitHomo sapiens (human)
Histone-lysine N-methyltransferase SETD1BEC 2.1.1.354; Lysine N-methyltransferase 2G; SET domain-containing protein 1B; hSET1BHomo sapiens (human)
Integrin alpha-IIbGPalpha IIb; GPIIb; Platelet membrane glycoprotein IIbHomo sapiens (human)
Protein kinase C theta typeEC 2.7.11.13; nPKC-thetaHomo sapiens (human)
Histone deacetylase 1HD1; EC 3.5.1.98Homo sapiens (human)
Transcription factor NF-E2 45 kDa subunitLeucine zipper protein NF-E2; Nuclear factor, erythroid-derived 2 45 kDa subunit; p45 NF-E2Homo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Histone acetyltransferase KAT2BEC 2.3.1.48; Histone acetyltransferase PCAF; Histone acetylase PCAF; Lysine acetyltransferase 2B; P300/CBP-associated factor; P/CAF; Spermidine acetyltransferase KAT2B; 2.3.1.57Homo sapiens (human)
Protein arginine N-methyltransferase 6EC 2.1.1.319; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6Homo sapiens (human)
Histone-lysine N-methyltransferase 2CLysine N-methyltransferase 2C; EC 2.1.1.354; Homologous to ALR protein; Myeloid/lymphoid or mixed-lineage leukemia protein 3Homo sapiens (human)
Histone H4Homo sapiens (human)
Nuclear receptor subfamily 4 group A member 3Mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; Nuclear hormone receptor NOR-1Homo sapiens (human)
Protein arginine N-methyltransferase 1EC 2.1.1.319; Histone-arginine N-methyltransferase PRMT1; Interferon receptor 1-bound protein 4Homo sapiens (human)
Histone-lysine N-methyltransferase SETD1AEC 2.1.1.354; Lysine N-methyltransferase 2F; SET domain-containing protein 1A; hSET1A; Set1/Ash2 histone methyltransferase complex subunit SET1Homo sapiens (human)
Platelet glycoprotein Ib alpha chainGP-Ib alpha; GPIb-alpha; GPIbA; Glycoprotein Ibalpha; Antigen CD42b-alphaHomo sapiens (human)
Erythroid transcription factorEryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding proteinHomo sapiens (human)
Myosin regulatory light polypeptide 920 kDa myosin light chain; LC20; MLC-2C; Myosin RLC; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1Homo sapiens (human)
Zinc finger protein ZFPM1Friend of GATA protein 1; FOG-1; Friend of GATA 1; Zinc finger protein 89A; Zinc finger protein multitype 1Homo sapiens (human)
Helicase MOV-10EC 3.6.4.13; Armitage homolog; Moloney leukemia virus 10 proteinHomo sapiens (human)

Compounds (1)

CompoundDescription
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)