| Protein | Synonyms | Taxonomy |
|---|
| Neutrophil cytosol factor 1 | NCF-1; 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3 and PX domain-containing protein 1A; p47-phox | Homo sapiens (human) |
| Ras-related C3 botulinum toxin substrate 2 | GX; Small G protein; p21-Rac2 | Homo sapiens (human) |
| Lactoperoxidase | LPO; EC 1.11.1.7; Salivary peroxidase; SPO | Homo sapiens (human) |
| Myeloperoxidase | MPO; EC 1.11.2.2 | Homo sapiens (human) |
| Natural resistance-associated macrophage protein 1 | NRAMP 1; Solute carrier family 11 member 1 | Homo sapiens (human) |
| Neutrophil cytosol factor 2 | NCF-2; 67 kDa neutrophil oxidase factor; NADPH oxidase activator 2; Neutrophil NADPH oxidase factor 2; p67-phox | Homo sapiens (human) |
| Neutrophil cytosol factor 4 | NCF-4; Neutrophil NADPH oxidase factor 4; SH3 and PX domain-containing protein 4; p40-phox; p40phox | Homo sapiens (human) |
| V-type proton ATPase subunit F | V-ATPase subunit F; V-ATPase 14 kDa subunit; Vacuolar proton pump subunit F | Homo sapiens (human) |
| Voltage-gated hydrogen channel 1 | Hydrogen voltage-gated channel 1; HV1; Voltage sensor domain-only protein | Homo sapiens (human) |
| V-type proton ATPase 21 kDa proteolipid subunit | V-ATPase 21 kDa proteolipid subunit; Vacuolar proton pump 21 kDa proteolipid subunit; hATPL | Homo sapiens (human) |
| V-type proton ATPase subunit H | V-ATPase subunit H; Nef-binding protein 1; NBP1; Protein VMA13 homolog; V-ATPase 50/57 kDa subunits; Vacuolar proton pump subunit H; Vacuolar proton pump subunit SFD | Homo sapiens (human) |
| V-type proton ATPase subunit D | V-ATPase subunit D; V-ATPase 28 kDa accessory protein; Vacuolar proton pump subunit D | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| Nitric Oxide | A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP. |
| Arginine | An essential amino acid that is physiologically active in the L-form. |
| nitrous acid | Nitrous acid (HNO2). A weak acid that exists only in solution. It can form water-soluble nitrites and stable esters. (From Merck Index, 11th ed) |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| chlorine | An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family. |
| Superoxides | Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| nitrosonium ion | a nitric oxide congener |
| nitrites | Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed) |
| hydroxide ion | |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| s-nitrosoglutathione | A sulfur-containing alkyl thionitrite that is one of the NITRIC OXIDE DONORS. |
| nitryl chloride | |
| hypothiocyanite ion | structure |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| acetylglucosamine | The N-acetyl derivative of glucosamine. |
| hypochlorous acid | An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent. |
| perhydroxyl radical | |
| n-acetylmuramic acid | RN given refers to D-Glucopyranose, (R)-isomer |
| nitrogen trioxide | |
| Peroxynitrite | |
| hydroxyl radical | The univalent radical OH. Hydroxyl radical is a potent oxidizing agent. |
| heme | The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. |
| Heme | The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. |
| nitrosoperoxycarbonate | a peroxynitrite and carbon dioxide adduct involved in oxidative DNA damage |
| thiocyanate | RN given refers to parent cpd |