Page last updated: 2024-10-06

RIPK1-mediated regulated necrosis

Proteins (21)

ProteinSynonymsTaxonomy
E3 ubiquitin-protein ligase parkinParkin; EC 2.3.2.31; Parkin RBR E3 ubiquitin-protein ligase; Parkinson juvenile disease protein 2; Parkinson disease protein 2Homo sapiens (human)
Flotillin-1Homo sapiens (human)
Heat shock protein HSP 90-alphaEC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38Homo sapiens (human)
Caspase-8CASP-8; EC 3.4.22.61; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACHHomo sapiens (human)
Non-structural protein 1NS1; NS1AInfluenza A virus (A/Puerto Rico/8/1934(H1N1))
Receptor-interacting serine/threonine-protein kinase 1EC 2.7.11.1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1Homo sapiens (human)
E3 ubiquitin-protein ligase Itchy homologItch; EC 2.3.2.26; Atrophin-1-interacting protein 4; AIP4; HECT-type E3 ubiquitin transferase Itchy homolog; NFE2-associated polypeptide 1; NAPP1Homo sapiens (human)
Ribonucleoside-diphosphate reductase large subunitR1; EC 1.17.4.1; Ribonucleotide reductase large subunitHuman alphaherpesvirus 1 strain 17
Mixed lineage kinase domain-like proteinhMLKLHomo sapiens (human)
Receptor-interacting serine/threonine-protein kinase 3EC 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3Homo sapiens (human)
Syntenin-1Melanoma differentiation-associated protein 9; MDA-9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; TACIP18; Scaffold protein Pbp1; Syndecan-binding protein 1Homo sapiens (human)
Hsp90 co-chaperone Cdc37Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37Homo sapiens (human)
TNF receptor-associated factor 2EC 2.3.2.27; E3 ubiquitin-protein ligase TRAF2; RING-type E3 ubiquitin transferase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3Homo sapiens (human)
FAS-associated death domain proteinFAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADDHomo sapiens (human)
Ubiquitin-conjugating enzyme E2 L3EC 2.3.2.23; E2 ubiquitin-conjugating enzyme L3; L-UBC; UbcH7; Ubiquitin carrier protein L3; Ubiquitin-conjugating enzyme E2-F1; Ubiquitin-protein ligase L3Homo sapiens (human)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunitEC 2.4.1.255; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; OGTHomo sapiens (human)
E3 ubiquitin-protein ligase CHIPEC 2.3.2.27; Antigen NY-CO-7; CLL-associated antigen KW-8; Carboxy terminus of Hsp70-interacting protein; RING-type E3 ubiquitin transferase CHIP; STIP1 homology and U box-containing protein 1Homo sapiens (human)
Flotillin-2Epidermal surface antigen; ESA; Membrane component chromosome 17 surface marker 1Homo sapiens (human)
Tumor necrosis factor receptor type 1-associated DEATH domain proteinTNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domainHomo sapiens (human)
Programmed cell death 6-interacting proteinPDCD6-interacting protein; ALG-2-interacting protein 1; ALG-2-interacting protein X; Hp95Homo sapiens (human)
E3 ubiquitin-protein ligase pellino homolog 1Pellino-1; EC 2.3.2.27; Pellino-related intracellular-signaling molecule; RING-type E3 ubiquitin transferase pellino homolog 1Homo sapiens (human)

Compounds (5)

CompoundDescription
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
myo-inositol 1,3,4,5,6-pentakisphosphate
inositol-1,3,4,6-tetrakisphosphatefor cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES