Page last updated: 2024-10-06

RHO GTPases activate PKNs

Proteins (21)

ProteinSynonymsTaxonomy
14-3-3 protein etaProtein AS1Homo sapiens (human)
3-phosphoinositide-dependent protein kinase 1hPDK1; EC 2.7.11.1Homo sapiens (human)
Lysine-specific histone demethylase 1AEC 1.14.99.66; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2; [histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1AHomo sapiens (human)
Androgen receptorDihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4Homo sapiens (human)
Serine/threonine-protein kinase PAK 1EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAKHomo sapiens (human)
M-phase inducer phosphatase 3EC 3.1.3.48; Dual specificity phosphatase Cdc25CHomo sapiens (human)
Serine/threonine-protein kinase N1EC 2.7.11.13; Protease-activated kinase 1; PAK-1; Protein kinase C-like 1; Protein kinase C-like PKN; Protein kinase PKN-alpha; Protein-kinase C-related kinase 1; Serine-threonine protein kinase NHomo sapiens (human)
14-3-3 protein theta14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1Homo sapiens (human)
Serine/threonine-protein phosphatase PP1-beta catalytic subunitPP-1B; PPP1CD; EC 3.1.3.16; EC 3.1.3.53Homo sapiens (human)
14-3-3 protein sigmaEpithelial cell marker protein 1; StratifinHomo sapiens (human)
Nuclear receptor coactivator 2NCoA-2; Class E basic helix-loop-helix protein 75; bHLHe75; Transcriptional intermediary factor 2; hTIF2Homo sapiens (human)
14-3-3 protein gammaProtein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Histone H4Homo sapiens (human)
Lysine-specific demethylase 4CEC 1.14.11.66; Gene amplified in squamous cell carcinoma 1 protein; GASC-1 protein; JmjC domain-containing histone demethylation protein 3C; Jumonji domain-containing protein 2C; [histone H3]-trimethyl-L-lysine(9) demethylase 4CHomo sapiens (human)
14-3-3 protein beta/alphaProtein 1054; Protein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
14-3-3 protein epsilon14-3-3EHomo sapiens (human)
14-3-3 protein zeta/deltaProtein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Myosin light polypeptide 617 kDa myosin light chain; LC17; Myosin light chain 3; MLC-3; Myosin light chain alkali 3; Myosin light chain A3; Smooth muscle and nonmuscle myosin light chain alkali 6Homo sapiens (human)
Protein phosphatase 1 regulatory subunit 12AMyosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunitHomo sapiens (human)
Protein phosphatase 1 regulatory subunit 12BMyosin phosphatase-targeting subunit 2; Myosin phosphatase target subunit 2Homo sapiens (human)
Protein phosphatase 1 regulatory subunit 14A17 kDa PKC-potentiated inhibitory protein of PP1; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI-17Homo sapiens (human)

Compounds (10)

CompoundDescription
Succinate
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
formaldehydeA highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
alpha-Ketoglutarate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.