Page last updated: 2024-10-06
RHO GTPases activate PAKs
Proteins (15)
| Protein | Synonyms | Taxonomy |
|---|
| Serine/threonine-protein kinase PAK 1 | EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK | Homo sapiens (human) |
| Myosin light chain kinase, smooth muscle | MLCK; smMLCK; EC 2.7.11.18; Kinase-related protein; KRP; Telokin | Homo sapiens (human) |
| Serine/threonine-protein kinase PAK 3 | EC 2.7.11.1; Beta-PAK; Oligophrenin-3; p21-activated kinase 3; PAK-3 | Homo sapiens (human) |
| LIM domain kinase 1 | LIMK-1; EC 2.7.11.1 | Homo sapiens (human) |
| Cell division control protein 42 homolog | EC 3.6.5.2; G25K GTP-binding protein | Homo sapiens (human) |
| Serine/threonine-protein phosphatase PP1-beta catalytic subunit | PP-1B; PPP1CD; EC 3.1.3.16; EC 3.1.3.53 | Homo sapiens (human) |
| Src substrate cortactin | Amplaxin; Oncogene EMS1 | Homo sapiens (human) |
| Ras-related C3 botulinum toxin substrate 1 | EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1 | Homo sapiens (human) |
| Calmodulin-1 | | Homo sapiens (human) |
| Serine/threonine-protein kinase PAK 2 | EC 2.7.11.1; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58 | Homo sapiens (human) |
| Myosin light polypeptide 6 | 17 kDa myosin light chain; LC17; Myosin light chain 3; MLC-3; Myosin light chain alkali 3; Myosin light chain A3; Smooth muscle and nonmuscle myosin light chain alkali 6 | Homo sapiens (human) |
| Protein phosphatase 1 regulatory subunit 12A | Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit | Homo sapiens (human) |
| Protein phosphatase 1 regulatory subunit 12B | Myosin phosphatase-targeting subunit 2; Myosin phosphatase target subunit 2 | Homo sapiens (human) |
| Filamin-A | FLN-A; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin | Homo sapiens (human) |
| Merlin | Moesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; Schwannomin | Homo sapiens (human) |
Compounds (6)
| Compound | Description |
|---|
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |