Page last updated: 2024-10-06

RHO GTPases activate PAKs

Proteins (15)

ProteinSynonymsTaxonomy
Serine/threonine-protein kinase PAK 1EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAKHomo sapiens (human)
Myosin light chain kinase, smooth muscleMLCK; smMLCK; EC 2.7.11.18; Kinase-related protein; KRP; TelokinHomo sapiens (human)
Serine/threonine-protein kinase PAK 3EC 2.7.11.1; Beta-PAK; Oligophrenin-3; p21-activated kinase 3; PAK-3Homo sapiens (human)
LIM domain kinase 1LIMK-1; EC 2.7.11.1Homo sapiens (human)
Cell division control protein 42 homologEC 3.6.5.2; G25K GTP-binding proteinHomo sapiens (human)
Serine/threonine-protein phosphatase PP1-beta catalytic subunitPP-1B; PPP1CD; EC 3.1.3.16; EC 3.1.3.53Homo sapiens (human)
Src substrate cortactinAmplaxin; Oncogene EMS1Homo sapiens (human)
Ras-related C3 botulinum toxin substrate 1EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1Homo sapiens (human)
Calmodulin-1Homo sapiens (human)
Serine/threonine-protein kinase PAK 2EC 2.7.11.1; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58Homo sapiens (human)
Myosin light polypeptide 617 kDa myosin light chain; LC17; Myosin light chain 3; MLC-3; Myosin light chain alkali 3; Myosin light chain A3; Smooth muscle and nonmuscle myosin light chain alkali 6Homo sapiens (human)
Protein phosphatase 1 regulatory subunit 12AMyosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunitHomo sapiens (human)
Protein phosphatase 1 regulatory subunit 12BMyosin phosphatase-targeting subunit 2; Myosin phosphatase target subunit 2Homo sapiens (human)
Filamin-AFLN-A; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filaminHomo sapiens (human)
MerlinMoesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; SchwannominHomo sapiens (human)

Compounds (6)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.