Page last updated: 2024-10-06

Pyruvate metabolism ( Pyruvate metabolism )

Proteins (30)

ProteinSynonymsTaxonomy
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialEC 2.3.1.12; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; PBC; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; M2 antigen complex 70 kDa subunit; Pyruvate dehydrogenase complex component E2; PDC-E2; PDCE2Homo sapiens (human)
4-trimethylaminobutyraldehyde dehydrogenaseTMABA-DH; TMABALDH; EC 1.2.1.47; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; 1.2.1.3; Gamma-aminobutyraldehyde dehydrogenase; 1.2.1.19; R-aminobutyraldehyde dehydrogenaseHomo sapiens (human)
Aldehyde dehydrogenase family 3 member A2EC 1.2.1.3; EC 1.2.1.94; Aldehyde dehydrogenase 10; Fatty aldehyde dehydrogenase; Microsomal aldehyde dehydrogenaseHomo sapiens (human)
Acetyl-coenzyme A synthetase, cytoplasmicEC 6.2.1.1; Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acetyl-CoA synthetase 1; AceCS1; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme; Propionate--CoA ligase; 6.2.1.17Homo sapiens (human)
Malonyl-CoA decarboxylase, mitochondrialMCD; EC 4.1.1.9Homo sapiens (human)
L-lactate dehydrogenase A chainLDH-A; EC 1.1.1.27; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59Homo sapiens (human)
Acetyl-CoA carboxylase 1ACC1; EC 6.4.1.2; Acetyl-Coenzyme A carboxylase alpha; ACC-alphaHomo sapiens (human)
NADP-dependent malic enzyme, mitochondrialNADP-ME; EC 1.1.1.40; Malic enzyme 3Homo sapiens (human)
Pyruvate dehydrogenase E1 component subunit beta, mitochondrialPDHE1-B; EC 1.2.4.1Homo sapiens (human)
Retinal dehydrogenase 1RALDH 1; RalDH1; EC 1.2.1.-; EC 1.2.1.36; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolicHomo sapiens (human)
Aldehyde dehydrogenase, mitochondrialEC 1.2.1.3; ALDH class 2; ALDH-E2; ALDHIHomo sapiens (human)
L-lactate dehydrogenase B chainLDH-B; EC 1.1.1.27; LDH heart subunit; LDH-H; Renal carcinoma antigen NY-REN-46Homo sapiens (human)
Hydroxyacylglutathione hydrolase-like proteinEC 3.1.2.-Homo sapiens (human)
Acetyl-CoA carboxylase 2EC 6.4.1.2; ACC-betaHomo sapiens (human)
Lactoylglutathione lyaseEC 4.4.1.5; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyaseHomo sapiens (human)
NADP-dependent malic enzymeNADP-ME; EC 1.1.1.40; Malic enzyme 1Homo sapiens (human)
Hydroxyacylglutathione hydrolase, mitochondrialEC 3.1.2.6; Glyoxalase II; Glx IIHomo sapiens (human)
Retinal dehydrogenase 2RALDH 2; RalDH2; EC 1.2.1.36; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II)Homo sapiens (human)
Aldehyde dehydrogenase X, mitochondrialEC 1.2.1.3; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1Homo sapiens (human)
L-lactate dehydrogenase C chainLDH-C; EC 1.1.1.27; Cancer/testis antigen 32; CT32; LDH testis subunit; LDH-XHomo sapiens (human)
Pyruvate dehydrogenase protein X component, mitochondrialDihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex; E3-binding protein; E3BP; Lipoyl-containing pyruvate dehydrogenase complex component X; proXHomo sapiens (human)
Dihydrolipoyl dehydrogenase, mitochondrialEC 1.8.1.4; Dihydrolipoamide dehydrogenase; Glycine cleavage system L proteinHomo sapiens (human)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrialEC 1.2.4.1; PDHE1-A type IHomo sapiens (human)
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrialEC 1.2.4.1; PDHE1-A type IIHomo sapiens (human)
Probable D-lactate dehydrogenase, mitochondrialDLD; Lactate dehydrogenase D; EC 1.1.2.4Homo sapiens (human)
NAD-dependent malic enzyme, mitochondrialNAD-ME; EC 1.1.1.38; Malic enzyme 2Homo sapiens (human)
Acylphosphatase-1EC 3.6.1.7; Acylphosphatase, erythrocyte isozyme; Acylphosphatase, organ-common type isozyme; Acylphosphate phosphohydrolase 1Homo sapiens (human)
Acylphosphatase-2EC 3.6.1.7; Acylphosphatase, muscle type isozyme; Acylphosphate phosphohydrolase 2Homo sapiens (human)
Alpha-aminoadipic semialdehyde dehydrogenaseAlpha-AASA dehydrogenase; EC 1.2.1.31; Aldehyde dehydrogenase family 7 member A1; 1.2.1.3; Antiquitin-1; Betaine aldehyde dehydrogenase; 1.2.1.8; Delta1-piperideine-6-carboxylate dehydrogenase; P6c dehydrogenaseHomo sapiens (human)
L-lactate dehydrogenase A-like 6BEC 1.1.1.27Homo sapiens (human)

Compounds (24)

CompoundDescription
phosphoric acidconcise etchant is 37% H3PO4
diphosphoric acid
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
l-lactic acid
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
GlutathioneA tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
acetic acidProduct of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
NADH
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
acetaldehydeA colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetyl phosphate
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
malonyl coenzyme aA coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.
lipoamideRN given refers to cpd without isomeric designation
pyruvaldehydeAn organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
malic acid
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
d-lactic acid
dihydrolipoamideRN given refers to cpd without isomeric designation
coenzyme a