Pyruvate Decarboxylation to Acetyl-CoA

Proteins (3)

Protein	Synonyms	Taxonomy
Dihydrolipoyl dehydrogenase	EC 1.8.1.4; Dihydrolipoamide dehydrogenase; E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; Glycine cleavage system L protein	Escherichia coli K-12
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex	EC 2.3.1.12; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; E2	Escherichia coli K-12
Pyruvate dehydrogenase E1 component	PDH E1 component; EC 1.2.4.1	Escherichia coli K-12

Compound	Description
hydronium ion
pyruvic acid	An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Carbon Dioxide	A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
NADH
Coenzyme A
NAD	A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
acetyl coenzyme a	Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.