Page last updated: 2024-10-06

Pyrimidine synthesis and deprivation pathway (COVID-19 Disease Maps)

Proteins (13)

ProteinSynonymsTaxonomy
Interferon alpha-1/13IFN-alpha-1/13; Interferon alpha-D; LeIF DHomo sapiens (human)
Interferon regulatory factor 3IRF-3Homo sapiens (human)
Double-strand break repair protein MRE11EC 3.1.-.-; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog AHomo sapiens (human)
Serine/threonine-protein kinase TBK1EC 2.7.11.1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1Homo sapiens (human)
Cyclic GMP-AMP synthasecGAMP synthase; cGAS; h-cGAS; EC 2.7.7.86; 2'3'-cGAMP synthase; Mab-21 domain-containing protein 1Homo sapiens (human)
Interferon betaIFN-beta; Fibroblast interferonHomo sapiens (human)
GTP-binding protein SAR1aCOPII-associated small GTPaseHomo sapiens (human)
Uridine 5'-monophosphate synthaseUMP synthaseHomo sapiens (human)
CAD proteinHomo sapiens (human)
Cytidine deaminaseEC 3.5.4.5; Cytidine aminohydrolaseHomo sapiens (human)
CTP synthase 1EC 6.3.4.2; CTP synthetase 1; UTP--ammonia ligase 1Homo sapiens (human)
DNA repair protein RAD50hRAD50; EC 3.6.-.-Homo sapiens (human)
WD repeat domain phosphoinositide-interacting protein 2WIPI-2; WIPI49-like protein 2Homo sapiens (human)

Compounds (26)

CompoundDescription
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
ubiquinol 1
teriflunomidea leflunomide metabolite
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
uridineA ribonucleoside in which RIBOSE is linked to URACIL.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
uridine triphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
phosphoribosyl pyrophosphateThe key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
guanosine triphosphateGuanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety.
deoxyuridine triphosphate
ubiquinone q1interacts with iron atom to form acceptor quinone complex
cytidine monophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
cytidine diphosphateCytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate.
cytidineA pyrimidine nucleoside that is composed of the base CYTOSINE linked to the five-carbon sugar D-RIBOSE.
cytidine triphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
thymidine monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
2'-deoxycytidine diphosphate
thymidine 5'-diphosphatesee also record for thymidine 3',5'-diphosphate, RN 2863-04-9
Uridine Monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
thymidine 5'-triphosphateRN given refers to parent cpd
2'-deoxyuridylic acidRN given refers to parent cpd
deoxyuridine triphosphate
2'-deoxycytidine 5'-triphosphateRN given refers to unlabeled parent cpd