Page last updated: 2024-10-06

Pyrimidine Nucleotides and Nucleosides metabolism ( Pyrimidine Nucleotides and Nucleosides metabolism )

Proteins (45)

ProteinSynonymsTaxonomy
Nucleoside diphosphate kinase, mitochondrialNDK; NDP kinase, mitochondrial; EC 2.7.4.6; Nucleoside diphosphate kinase D; NDPKD; nm23-H4Homo sapiens (human)
Uridine-cytidine kinase 2UCK 2; EC 2.7.1.48; Cytidine monophosphokinase 2; Testis-specific protein TSA903; Uridine monophosphokinase 2Homo sapiens (human)
Uridine-cytidine kinase 1 UCK 1; EC 2.7.1.48; Cytidine monophosphokinase 1; Uridine monophosphokinase 1Homo sapiens (human)
Thymidine kinase 2, mitochondrialEC 2.7.1.21; Mt-TKHomo sapiens (human)
Thymidylate synthaseTS; TSase; EC 2.1.1.45Homo sapiens (human)
Cytosolic purine 5'-nucleotidaseEC 3.1.3.5; Cytosolic 5'-nucleotidase IIHomo sapiens (human)
Single-stranded DNA cytosine deaminaseEC 3.5.4.38; Activation-induced cytidine deaminase; AID; Cytidine aminohydrolaseHomo sapiens (human)
5'(3')-deoxyribonucleotidase, mitochondrial5',3'-nucleotidase, mitochondrial; EC 3.1.3.-; Deoxy-5'-nucleotidase 2; dNT-2Homo sapiens (human)
Dihydropyrimidine dehydrogenase [NADP(+)]DHPDHase; DPD; EC 1.3.1.2; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenaseHomo sapiens (human)
Ectonucleoside triphosphate diphosphohydrolase 3NTPDase 3; EC 3.6.1.5; CD39 antigen-like 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPDase 3; Ecto-ATPase 3; Ecto-apyrase 3; HB6Homo sapiens (human)
Nucleoside diphosphate kinase ANDK A; NDP kinase A; EC 2.7.4.6; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; NM23-H1; Tumor metastatic process-associated proteinHomo sapiens (human)
Thymidine phosphorylaseTP; EC 2.4.2.4; Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPaseHomo sapiens (human)
Nucleoside diphosphate kinase BNDK B; NDP kinase B; EC 2.7.4.6; C-myc purine-binding transcription factor PUF; Histidine protein kinase NDKB; 2.7.13.3; nm23-H2Homo sapiens (human)
Ribonucleoside-diphosphate reductase large subunitEC 1.17.4.1; Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large subunitHomo sapiens (human)
Deoxycytidine kinasedCK; EC 2.7.1.74; Deoxyadenosine kinase; 2.7.1.76; Deoxyguanosine kinase; 2.7.1.113Homo sapiens (human)
UMP-CMP kinase EC 2.7.4.14; Deoxycytidylate kinase; CK; dCMP kinase; Nucleoside-diphosphate kinase; 2.7.4.6; Uridine monophosphate/cytidine monophosphate kinase; UMP/CMP kinase; UMP/CMPKHomo sapiens (human)
Ribonucleoside-diphosphate reductase subunit M2EC 1.17.4.1; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunitHomo sapiens (human)
Deoxycytidylate deaminaseEC 3.5.4.12; dCMP deaminaseHomo sapiens (human)
Beta-ureidopropionaseEC 3.5.1.6; BUP-1; Beta-alanine synthase; N-carbamoyl-beta-alanine amidohydrolaseHomo sapiens (human)
Ectonucleoside triphosphate diphosphohydrolase 4NTPDase 4; EC 3.6.1.15; EC 3.6.1.6; Golgi UDPase; Lysosomal apyrase-like protein of 70 kDa; Uridine-diphosphatase; UDPase; 3.6.1.42Homo sapiens (human)
Ectonucleoside triphosphate diphosphohydrolase 5NTPDase 5; EC 3.6.1.6; CD39 antigen-like 4; ER-UDPase; Guanosine-diphosphatase ENTPD5; GDPase ENTPD5; 3.6.1.42; Nucleoside diphosphatase; Uridine-diphosphatase ENTPD5; UDPase ENTPD5Homo sapiens (human)
Thymidine kinase, cytosolicEC 2.7.1.21Homo sapiens (human)
Uridine 5'-monophosphate synthaseUMP synthaseHomo sapiens (human)
5'-nucleotidase5'-NT; EC 3.1.3.5; Ecto-5'-nucleotidaseHomo sapiens (human)
Thymidylate kinaseEC 2.7.4.9; dTMP kinaseHomo sapiens (human)
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrialdUTPase; EC 3.6.1.23; dUTP pyrophosphataseHomo sapiens (human)
Ectonucleoside triphosphate diphosphohydrolase 1NTPDase 1; EC 3.6.1.5; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigenHomo sapiens (human)
Dihydroorotate dehydrogenase (quinone), mitochondrialDHOdehase; EC 1.3.5.2; Dihydroorotate oxidaseHomo sapiens (human)
CAD proteinHomo sapiens (human)
DihydropyrimidinaseDHP; DHPase; EC 3.5.2.2; Dihydropyrimidine amidohydrolase; HydantoinaseHomo sapiens (human)
Cytidine deaminaseEC 3.5.4.5; Cytidine aminohydrolaseHomo sapiens (human)
Uridine phosphorylase 1UPase 1; UrdPase 1; EC 2.4.2.3Homo sapiens (human)
5'(3')-deoxyribonucleotidase, cytosolic typeEC 3.1.3.-; Cytosolic 5',3'-pyrimidine nucleotidase; Deoxy-5'-nucleotidase 1; dNT-1Homo sapiens (human)
Inosine triphosphate pyrophosphatase ITPase; Inosine triphosphatase; EC 3.6.1.9; Non-canonical purine NTP pyrophosphatase; Non-standard purine NTP pyrophosphatase; Nucleoside-triphosphate diphosphatase; Nucleoside-triphosphate pyrophosphatase; NTPase; Putative oncogene protein hlc14-06-pHomo sapiens (human)
Nucleoside diphosphate kinase 7NDK 7; NDP kinase 7; EC 2.7.4.6; nm23-H7Homo sapiens (human)
Ectonucleoside triphosphate diphosphohydrolase 6NTPDase 6; EC 3.6.1.6; CD39 antigen-like 2Homo sapiens (human)
Soluble calcium-activated nucleotidase 1SCAN-1; EC 3.6.1.6; Apyrase homolog; Putative MAPK-activating protein PM09; Putative NF-kappa-B-activating protein 107Homo sapiens (human)
CTP synthase 1EC 6.3.4.2; CTP synthetase 1; UTP--ammonia ligase 1Homo sapiens (human)
CTP synthase 2EC 6.3.4.2; CTP synthetase 2; UTP--ammonia ligase 2Homo sapiens (human)
Nucleoside diphosphate kinase 6NDK 6; NDP kinase 6; EC 2.7.4.6; Inhibitor of p53-induced apoptosis-alpha; IPIA-alpha; nm23-H6Homo sapiens (human)
Nucleoside diphosphate kinase homolog 5NDK-H 5; NDP kinase homolog 5; Inhibitor of p53-induced apoptosis-beta; IPIA-beta; Testis-specific nm23 homolog; nm23-H5Homo sapiens (human)
Nucleoside diphosphate kinase 3NDK 3; NDP kinase 3; EC 2.7.4.6; DR-nm23; Nucleoside diphosphate kinase C; NDPKC; nm23-H3Homo sapiens (human)
Cytosolic 5'-nucleotidase 1BcN1B; EC 3.1.3.5; Autoimmune infertility-related protein; Cytosolic 5'-nucleotidase IB; cN-IBHomo sapiens (human)
Cytosolic 5'-nucleotidase 3AEC 3.1.3.5; 7-methylguanosine phosphate-specific 5'-nucleotidase; 7-methylguanosine nucleotidase; 3.1.3.91; Cytosolic 5'-nucleotidase 3; Cytosolic 5'-nucleotidase III; cN-III; Pyrimidine 5'-nucleotidase 1; P5'N-1; P5N-1; PN-I; Uridine 5'-monophosphate hydHomo sapiens (human)
GTP:AMP phosphotransferase AK3, mitochondrialEC 2.7.4.10; Adenylate kinase 3; AK 3; Adenylate kinase 3 alpha-like 1Homo sapiens (human)

Compounds (47)

CompoundDescription
phosphoric acidconcise etchant is 37% H3PO4
diphosphoric acid
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
aspartic acidOne of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
uridineA ribonucleoside in which RIBOSE is linked to URACIL.
uridine monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
uridine triphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
phosphoribosyl pyrophosphateThe key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
dihydrofolateRN given refers to (L)-isomer
n-carbamoyl-beta-alanineRN given refers to parent cpd
thymineOne of four constituent bases of DNA.
uracilOne of four nucleotide bases in the nucleic acid RNA.
deoxycytidineA nucleoside component of DNA composed of CYTOSINE and DEOXYRIBOSE.
deoxyuridine2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.
deoxycytidine monophosphateDeoxycytidine (dihydrogen phosphate). A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions.
deoxyuridine triphosphate
beta-ureidoisobutyric acidstructure given in first source
beta-alanineAn amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
carbamyl phosphateThe monoanhydride of carbamic acid with PHOSPHORIC ACID. It is an important intermediate metabolite and is synthesized enzymatically by CARBAMYL-PHOSPHATE SYNTHASE (AMMONIA) and CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING).
2-deoxyribose 1-phosphate, (alpha-d-erythro)-isomer
thymidineA nucleoside in which THYMINE is linked to DEOXYRIBOSE.
cytidine monophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
cytidine diphosphateCytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate.
cytidineA pyrimidine nucleoside that is composed of the base CYTOSINE linked to the five-carbon sugar D-RIBOSE.
cytidine triphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
dihydrouracil
orotic acidAn intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
thymidine monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
2'-deoxycytidine diphosphate
orotidylic acidstructure
thymidine 5'-diphosphatesee also record for thymidine 3',5'-diphosphate, RN 2863-04-9
L-dihydroorotate
creolinfrom refined coal tar oils
thymidine 5'-triphosphateRN given refers to parent cpd
2'-deoxyuridylic acidRN given refers to parent cpd
deoxyuridine triphosphate
2'-deoxycytidine 5'-triphosphateRN given refers to unlabeled parent cpd
ureidosuccinic acid, (L)-isomer
5,6-dihydrothymineRN given refers to parent cpd