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Proline catabolism

Proteins (3)

ProteinSynonymsTaxonomy
Hydroxyproline dehydrogenaseHYPDH; EC 1.5.5.3; Kidney and liver proline oxidase 1; HsPOX1; Probable proline dehydrogenase 2; 1.5.5.2; Probable proline oxidase 2Homo sapiens (human)
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrialP5C dehydrogenase; EC 1.2.1.88; Aldehyde dehydrogenase family 4 member A1; L-glutamate gamma-semialdehyde dehydrogenaseHomo sapiens (human)
Proline dehydrogenase 1, mitochondrialEC 1.5.5.2; Proline oxidase; Proline oxidase 2; p53-induced gene 6 proteinHomo sapiens (human)

Compounds (8)

CompoundDescription
hydronium ion
NADH
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
1,5-dihydro-FADchromophore component of E coli DNA photolyase
delta-1-pyrroline-5-carboxylate(L)-isomer is the biologically active form; RN given refers to cpd without isomeric designation; structure
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
glutamate
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)