Page last updated: 2024-10-06

Processive synthesis on the C-strand of the telomere

Proteins (16)

ProteinSynonymsTaxonomy
Werner syndrome ATP-dependent helicaseEC 3.6.4.12; DNA helicase, RecQ-like type 3; RecQ3; Exonuclease WRN; 3.1.-.-; RecQ protein-like 2Homo sapiens (human)
DNA polymerase delta subunit 4DNA polymerase delta subunit p12Homo sapiens (human)
Protection of telomeres protein 1hPot1; POT1-like telomere end-binding proteinHomo sapiens (human)
Replication protein A 70 kDa DNA-binding subunitRP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding proteinHomo sapiens (human)
DNA replication ATP-dependent helicase/nuclease DNA2hDNA2; DNA replication ATP-dependent helicase-like homologHomo sapiens (human)
Proliferating cell nuclear antigenPCNA; CyclinHomo sapiens (human)
DNA ligase 1EC 6.5.1.1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1Homo sapiens (human)
DNA polymerase delta catalytic subunitEC 2.7.7.7; 3'-5' exodeoxyribonuclease; 3.1.11.-; DNA polymerase subunit delta p125Homo sapiens (human)
Flap endonuclease 1FEN-1; EC 3.1.-.-; DNase IV; Flap structure-specific endonuclease 1; Maturation factor 1; MF1; hFEN-1Homo sapiens (human)
Telomeric repeat-binding factor 2-interacting protein 1TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; Dopamine receptor-interacting protein 5; Repressor/activator protein 1 homolog; RAP1 homolog; hRap1Homo sapiens (human)
Replication protein A 32 kDa subunitRP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34Homo sapiens (human)
Replication protein A 14 kDa subunitRP-A p14; Replication factor A protein 3; RF-A protein 3Homo sapiens (human)
DNA polymerase delta subunit 2DNA polymerase delta subunit p50Homo sapiens (human)
DNA polymerase delta subunit 3DNA polymerase delta subunit C; DNA polymerase delta subunit p66; DNA polymerase delta subunit p68Homo sapiens (human)
Adrenocortical dysplasia protein homologPOT1 and TIN2-interacting proteinHomo sapiens (human)
TERF1-interacting nuclear factor 2TRF1-interacting nuclear protein 2Homo sapiens (human)

Compounds (13)

CompoundDescription
hydronium ion
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
deoxyguanosine triphosphate
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
thymidine 5'-triphosphateRN given refers to parent cpd
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Uridine Monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
2'-deoxycytidine 5'-triphosphateRN given refers to unlabeled parent cpd
deoxyadenosine diphosphateRN given refers to parent cpd.