Page last updated: 2024-10-06

Presenilin action in Notch and Wnt signaling

Proteins (46)

ProteinSynonymsTaxonomy
Low-density lipoprotein receptor-related protein 6LRP-6Homo sapiens (human)
Proto-oncogene Wnt-1Proto-oncogene Int-1 homologHomo sapiens (human)
Recombining binding protein suppressor of hairlessCBF-1; J kappa-recombination signal-binding protein; RBP-J kappa; RBP-J; RBP-JK; Renal carcinoma antigen NY-REN-30Homo sapiens (human)
G1/S-specific cyclin-D1B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogeneHomo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
Mitogen-activated protein kinase 1MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2Homo sapiens (human)
Glycogen synthase kinase-3 betaGSK-3 beta; EC 2.7.11.26; Serine/threonine-protein kinase GSK3B; 2.7.11.1Homo sapiens (human)
Histone deacetylase 1HD1; EC 3.5.1.98Homo sapiens (human)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1Homo sapiens (human)
NicastrinHomo sapiens (human)
Gamma-secretase subunit APH-1AAPH-1a; Aph-1alpha; Presenilin-stabilization factorHomo sapiens (human)
Axin-1Axis inhibition protein 1; hAxinHomo sapiens (human)
Mitogen-activated protein kinase kinase kinase 7EC 2.7.11.25; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1Homo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
Casein kinase I isoform alphaCKI-alpha; EC 2.7.11.1; CK1Homo sapiens (human)
Presenilin-1PS-1; EC 3.4.23.-; Protein S182Homo sapiens (human)
Casein kinase II subunit alphaCK II alpha; EC 2.7.11.1Homo sapiens (human)
Peroxisome proliferator-activated receptor deltaPPAR-delta; NUCI; Nuclear hormone receptor 1; NUC1; Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta; PPAR-betaHomo sapiens (human)
Gamma-secretase subunit APH-1BAPH-1b; Aph-1beta; Presenilin-stabilization factor-likeHomo sapiens (human)
Gamma-secretase subunit PEN-2Presenilin enhancer protein 2Homo sapiens (human)
Serine/threonine-protein kinase NLKEC 2.7.11.24; Nemo-like kinase; Protein LAK1Homo sapiens (human)
Segment polarity protein dishevelled homolog DVL-1Dishevelled-1; DSH homolog 1Homo sapiens (human)
Dickkopf-related protein 1Dickkopf-1; Dkk-1; hDkk-1; SKHomo sapiens (human)
C-terminal-binding protein 1CtBP1; EC 1.1.1.-Homo sapiens (human)
Disintegrin and metalloproteinase domain-containing protein 10ADAM 10; EC 3.4.24.81; CDw156; Kuzbanian protein homolog; Mammalian disintegrin-metalloproteaseHomo sapiens (human)
Myc proto-oncogene proteinClass E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64Homo sapiens (human)
Adenomatous polyposis coli proteinProtein APC; Deleted in polyposis 2.5Homo sapiens (human)
Catenin beta-1Beta-cateninHomo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Frizzled-1Fz-1; hFz1; FzE1Homo sapiens (human)
Hepatocyte nuclear factor 1-alphaHNF-1-alpha; HNF-1A; Liver-specific transcription factor LF-B1; LFB1; Transcription factor 1; TCF-1Homo sapiens (human)
Proto-oncogene c-FosCellular oncogene fos; G0/G1 switch regulatory protein 7Homo sapiens (human)
Neurogenic locus notch homolog protein 1Notch 1; hN1; Translocation-associated notch protein TAN-1Homo sapiens (human)
E3 ubiquitin-protein ligase NEDD4EC 2.3.2.26; Cell proliferation-inducing gene 53 protein; HECT-type E3 ubiquitin transferase NEDD4; Neural precursor cell expressed developmentally down-regulated protein 4; NEDD-4Homo sapiens (human)
TLE family member 5Amino-terminal enhancer of split; Amino enhancer of split; Gp130-associated protein GAM; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; TLE family member 5, transcriptional modulatorHomo sapiens (human)
Protein naked cuticle homolog 1Naked-1; hNkd; hNkd1Homo sapiens (human)
Dickkopf-related protein 2Dickkopf-2; Dkk-2; hDkk-2Homo sapiens (human)
Transducin-like enhancer protein 1E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1Homo sapiens (human)
Delta-like protein 1Drosophila Delta homolog 1; Delta1; H-Delta-1Homo sapiens (human)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoformPP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-deltaHomo sapiens (human)
E3 ubiquitin-protein ligase DTX1EC 2.3.2.27; Protein deltex-1; Deltex1; hDTX1; RING-type E3 ubiquitin transferase DTX1Homo sapiens (human)
Kremen protein 2Dickkopf receptor 2; Kringle domain-containing transmembrane protein 2; Kringle-containing protein marking the eye and the noseHomo sapiens (human)
Proto-oncogene FRAT1Frequently rearranged in advanced T-cell lymphomas 1; FRAT-1Homo sapiens (human)
F-box/WD repeat-containing protein 11F-box and WD repeats protein beta-TrCP2; F-box/WD repeat-containing protein 1B; Homologous to Slimb protein; HOSHomo sapiens (human)
F-box/WD repeat-containing protein 1AE3RSIkappaB; Epididymis tissue protein Li 2a; F-box and WD repeats protein beta-TrCP; pIkappaBalpha-E3 receptor subunitHomo sapiens (human)
Wnt inhibitory factor 1WIF-1Homo sapiens (human)

Compounds (0)

CompoundDescription