Pathways > Pre-NOTCH Expression and Processing
Page last updated: 2024-10-06

Pre-NOTCH Expression and Processing

Proteins (24)

ProteinSynonymsTaxonomy
Runt-related transcription factor 1Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor Homo sapiens (human)
Recombining binding protein suppressor of hairlessCBF-1; J kappa-recombination signal-binding protein; RBP-J kappa; RBP-J; RBP-JK; Renal carcinoma antigen NY-REN-30Homo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
G1/S-specific cyclin-D1B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogeneHomo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
FurinEC 3.4.21.75; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACEHomo sapiens (human)
Protein kinase C iota typeEC 2.7.11.13; Atypical protein kinase C-lambda/iota; PRKC-lambda/iota; aPKC-lambda/iota; nPKC-iotaHomo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
ETS-related transcription factor Elf-3E74-like factor 3; Epithelial-restricted with serine box; Epithelium-restricted Ets protein ESX; Epithelium-specific Ets transcription factor 1; ESE-1Homo sapiens (human)
Neurogenic locus notch homolog protein 3Notch 3Homo sapiens (human)
Beta-1,4-galactosyltransferase 1Beta-1,4-GalTase 1; Beta4Gal-T1; b4Gal-T1; EC 2.4.1.-; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; 2.4.1.38; Lactose synthase A protein; 2.4.1.22; N-acetyllactoHomo sapiens (human)
Histone H4Homo sapiens (human)
NAD-dependent protein deacetylase sirtuin-6EC 2.3.1.286; Regulatory protein SIR2 homolog 6; SIR2-like protein 6Homo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Neurogenic locus notch homolog protein 4Notch 4; hNotch4Homo sapiens (human)
GDP-fucose protein O-fucosyltransferase 1EC 2.4.1.221; Peptide-O-fucosyltransferase 1; O-FucT-1Homo sapiens (human)
Neurogenic locus notch homolog protein 1Notch 1; hN1; Translocation-associated notch protein TAN-1Homo sapiens (human)
Neurogenic locus notch homolog protein 2Notch 2; hN2Homo sapiens (human)
Ras-related protein Rab-6ARab-6Homo sapiens (human)
Transmembrane emp24 domain-containing protein 2Membrane protein p24A; p24; p24 family protein beta-1; p24beta1Homo sapiens (human)
SNW domain-containing protein 1Nuclear protein SkiP; Nuclear receptor coactivator NCoA-62; Ski-interacting proteinHomo sapiens (human)
Protein O-glucosyltransferase 1EC 2.4.1.376; CAP10-like 46 kDa protein; hCLP46; KTEL motif-containing protein 1; Myelodysplastic syndromes relative protein; O-glucosyltransferase Rumi homolog; hRumi; Protein O-xylosyltransferase POGLUT1; 2.4.2.63Homo sapiens (human)
Helicase MOV-10EC 3.6.4.13; Armitage homolog; Moloney leukemia virus 10 proteinHomo sapiens (human)
Protein sel-1 homolog 1Suppressor of lin-12-like protein 1; Sel-1LHomo sapiens (human)

Compounds (9)

CompoundDescription
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
guanosine diphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
o-acetyl-adp-riboseAn acetyl ester of ADENOSINE DIPHOSPHATE RIBOSE formed during NAD-dependent deacetylation of proteins by SIRTUINS. The acetate group resides on the ribose ring where nicotinamide was cleaved from NAD during the reaction. Several isomers of O-acetyl-ADP-ribose have been isolated from the reaction.
cytarabineA pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
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