Page last updated: 2024-10-06

Porphyrin_metabolism ( Porphyrin metabolism )

Proteins (7)

ProteinSynonymsTaxonomy
Porphobilinogen deaminasePBG-D; EC 2.5.1.61; Hydroxymethylbilane synthase; HMBS; Pre-uroporphyrinogen synthaseHomo sapiens (human)
Ferrochelatase, mitochondrialEC 4.99.1.1; Heme synthase; Protoheme ferro-lyaseHomo sapiens (human)
Uroporphyrinogen decarboxylaseUPD; URO-D; EC 4.1.1.37Homo sapiens (human)
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrialCOX; Coprogen oxidase; Coproporphyrinogenase; EC 1.3.3.3Homo sapiens (human)
Delta-aminolevulinic acid dehydrataseALADH; EC 4.2.1.24; Porphobilinogen synthaseHomo sapiens (human)
Protoporphyrinogen oxidasePPO; EC 1.3.3.4Homo sapiens (human)
Uroporphyrinogen-III synthaseUROIIIS; UROS; EC 4.2.1.75; Hydroxymethylbilane hydrolyase [cyclizing]; Uroporphyrinogen-III cosynthaseHomo sapiens (human)

Compounds (13)

CompoundDescription
hydronium ion
aminolevulinic acidA compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
porphobilinogen
uroporphyrinogen iii
protoporphyrinogen
coproporphyrinogen iii
protoporphyrin ixRN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
hydroxymethylbilanetetrapyrrole intermediate in pigment biosynthesis by Euglena gracilis; universal intermediate in biosynthesis of uroporphyrinogen III; structure given in first source