Pathways > Phospholipid Biosynthesis
Page last updated: 2024-10-06

Phospholipid Biosynthesis

Proteins (25)

ProteinSynonymsTaxonomy
Diacylglycerol kinase alphaDAG kinase alpha; EC 2.7.1.107; 80 kDa diacylglycerol kinase; Diglyceride kinase alpha; DGK-alphaHomo sapiens (human)
Phospholipase A2 group XV1-O-acylceramide synthase; ACS; LCAT-like lysophospholipase; LLPL; 3.1.1.5; Lysophospholipase 3; Lysosomal phospholipase A and acyltransferase; 2.3.1.-; 3.1.1.32; 3.1.1.4; Lysosomal phospholipase A2; LPLA2Homo sapiens (human)
Group IID secretory phospholipase A2GIID sPLA2; sPLA2-IID; EC 3.1.1.4; PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA, stroma-associated homologHomo sapiens (human)
1-acyl-sn-glycerol-3-phosphate acyltransferase alphaEC 2.3.1.51; 1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT 1; Lysophosphatidic acid acyltransferase alpha; LPAAT-alpha; Protein G15Homo sapiens (human)
Cytosolic phospholipase A2 betacPLA2-beta; EC 3.1.1.4; Lysophospholipase A1 group IVB; 3.1.1.5; Phospholipase A2 group IVBHomo sapiens (human)
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1EC 3.1.3.27; PTEN-like phosphatase; Phosphoinositide lipid phosphatase; Protein-tyrosine phosphatase mitochondrial 1; 3.1.3.16; 3.1.3.48Homo sapiens (human)
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmicGPD-C; GPDH-C; EC 1.1.1.8Homo sapiens (human)
Phospholipase D2PLD 2; hPLD2; EC 3.1.4.4; Choline phosphatase 2; PLD1C; Phosphatidylcholine-hydrolyzing phospholipase D2Homo sapiens (human)
Acyl-protein thioesterase 1APT-1; hAPT1; EC 3.1.2.-; Lysophospholipase 1; Lysophospholipase I; LPL-I; LysoPLA IHomo sapiens (human)
Choline kinase alphaCK; EC 2.7.1.32; CHETK-alpha; Ethanolamine kinase; EK; 2.7.1.82Homo sapiens (human)
Phosphoethanolamine/phosphocholine phosphataseEC 3.1.3.75Homo sapiens (human)
Choline O-acetyltransferaseCHOACTase; ChAT; Choline acetylase; EC 2.3.1.6Homo sapiens (human)
Choline-phosphate cytidylyltransferase AEC 2.7.7.15; CCT-alpha; CTP:phosphocholine cytidylyltransferase A; CCT A; CT A; Phosphorylcholine transferase AHomo sapiens (human)
Glycerol-3-phosphate acyltransferase 1, mitochondrialGPAT-1; EC 2.3.1.15Homo sapiens (human)
Glycerol-3-phosphate dehydrogenase, mitochondrialGPD-M; GPDH-M; EC 1.1.5.3; mitohondrial glycerophosphate dehydrogenase gene; mGDH; mtGPDHomo sapiens (human)
Cardiolipin synthase (CMP-forming)CLS; EC 2.7.8.41; Protein GCD10 homologHomo sapiens (human)
Phosphatidylethanolamine N-methyltransferasePEAMT; PEMT; EC 2.1.1.17; EC 2.1.1.71; PEMT2; Phospholipid methyltransferase; PLMTHomo sapiens (human)
Phospholipid phosphatase 1EC 3.1.3.-; EC 3.1.3.106; EC 3.1.3.4; EC 3.1.3.81; Lipid phosphate phosphohydrolase 1; PAP2-alpha; Phosphatidate phosphohydrolase type 2a; Phosphatidic acid phosphatase 2a; PAP-2a; PAP2aHomo sapiens (human)
Phosphatidylserine synthase 1PSS-1; PtdSer synthase 1; EC 2.7.8.29; Serine-exchange enzyme IHomo sapiens (human)
Phosphatidylserine synthase 2PSS-2; PtdSer synthase 2; EC 2.7.8.29; Serine-exchange enzyme IIHomo sapiens (human)
CDP-diacylglycerol--inositol 3-phosphatidyltransferaseEC 2.7.8.11; Phosphatidylinositol synthase; PI synthase; PtdIns synthaseHomo sapiens (human)
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrialEC 2.7.8.5; Phosphatidylglycerophosphate synthase 1; PGP synthase 1Homo sapiens (human)
Phosphatidate cytidylyltransferase 1EC 2.7.7.41; CDP-DAG synthase 1; CDP-DG synthase 1; CDP-diacylglycerol synthase 1; CDS 1; CDP-diglyceride pyrophosphorylase 1; CDP-diglyceride synthase 1; CTP:phosphatidate cytidylyltransferase 1Homo sapiens (human)
Glycerophosphodiester phosphodiesterase 1Glycerophosphoinositol glycerophosphodiesterase GDE1; 3.1.4.44; Lysophospholipase D GDE1; 3.1.4.-; Membrane-interacting protein of RGS16; RGS16-interacting membrane proteinHomo sapiens (human)
Phosphatidylserine decarboxylase proenzyme, mitochondrialEC 4.1.1.65Homo sapiens (human)

Compounds (25)

CompoundDescription
phosphorylcholineCalcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
Orthophosphate
cytidine diphosphate cholineDonor of choline in biosynthesis of choline-containing phosphoglycerides.
AcetylcholineA neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
cholineA basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
NADH
alpha-glycerophosphoric acid
colfosceril palmitateused in the treatment of unilateral pulmonary interstitial emphysema; component of Exosurf
hydroquinone
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
1-palmitoylphosphatidylethanolamine, (R)-isomer
Coenzyme A
Palmitoyl Coenzyme AA fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.
dipalmitoylphosphatidylserine
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine
Phosphatidic Acid
guanylyl-(3'-5')-guanosine
quinone
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
1-palmitoyl-sn-glycerol 3-phosphate
dihydroxyacetone phosphateAn important intermediate in lipid biosynthesis and in glycolysis.
ethanolamineA viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.
lyso-pc
ATP Binding Cassette Transporter, Subfamily B, Member 1A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).
CardiolipinsAcidic phospholipids composed of two molecules of phosphatidic acid covalently linked to a molecule of glycerol. They occur primarily in mitochondrial inner membranes and in bacterial plasma membranes. They are the main antigenic components of the Wassermann-type antigen that is used in nontreponemal SYPHILIS SERODIAGNOSIS.
chemdatabank.com