Page last updated: 2024-10-06

Phosphate bond hydrolysis by NUDT proteins

Proteins (4)

ProteinSynonymsTaxonomy
Nucleotide triphosphate diphosphatase NUDT15EC 3.6.1.9; MutT homolog 2; MTH2; Nucleoside diphosphate-linked moiety X motif 15; Nudix motif 15; Nucleoside diphosphate-linked to another moiety X hydrolase 15; Nudix hydrolase 15Homo sapiens (human)
ADP-sugar pyrophosphataseEC 3.6.1.13; 8-oxo-dGDP phosphatase; 3.6.1.58; Nuclear ATP-synthesis protein NUDIX5; 2.7.7.96; Nucleoside diphosphate-linked moiety X motif 5; Nudix motif 5; hNUDT5; YSA1HHomo sapiens (human)
Manganese-dependent ADP-ribose/CDP-alcohol diphosphataseEC 3.6.1.13; EC 3.6.1.16; EC 3.6.1.53; ADPRibase-Mn; CDP-choline phosphohydrolaseHomo sapiens (human)
U8 snoRNA-decapping enzymeEC 3.6.1.62; IDP phosphatase; IDPase; 3.6.1.64; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; Nudix motif 16; Nudix hydrolase 16; U8 snoRNA-binding protein H29K; m7GpppN-mRNA hydrolaseHomo sapiens (human)

Compounds (16)

CompoundDescription
hydronium ion
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Orthophosphate
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
8-oxodeoxyadenosine triphosphate
Inosine MonophosphateInosine 5'-Monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.
deoxyinosine diphosphate
2-hydroxydeoxyadenosine triphosphate
TheophyllineA methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
Inosine DiphosphateAn inosine nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
8-oxo-7,8-dihydro-2'-deoxyguanosine-5'-monophosphate
8-oxo-7,8-dihydrodeoxyguanosine diphosphate
8-hydroxyguanosine triphosphate
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
2-hydroxydeoxyadenosine triphosphate