Page last updated: 2024-10-06

Pathways of nucleic acid metabolism and innate immune sensing

Proteins (15)

ProteinSynonymsTaxonomy
Mitochondrial antiviral-signaling proteinMAVS; CARD adapter inducing interferon beta; Cardif; Interferon beta promoter stimulator protein 1; IPS-1; Putative NF-kappa-B-activating protein 031N; Virus-induced-signaling adapter; VISAHomo sapiens (human)
Three-prime repair exonuclease 1EC 3.1.11.2; 3'-5' exonuclease TREX1; Deoxyribonuclease III; DNase IIIHomo sapiens (human)
Interferon regulatory factor 3IRF-3Homo sapiens (human)
Interferon-induced helicase C domain-containing protein 1EC 3.6.4.13; Clinically amyopathic dermatomyositis autoantigen 140 kDa; CADM-140 autoantigen; Helicase with 2 CARD domains; Helicard; Interferon-induced with helicase C domain protein 1; Melanoma differentiation-associated protein 5; MDA-5; Murabutide dowHomo sapiens (human)
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1dNTPase; EC 3.1.5.-; Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1; hSAMHD1Homo sapiens (human)
Stimulator of interferon genes proteinhSTING; Endoplasmic reticulum interferon stimulator; ERIS; Mediator of IRF3 activation; hMITA; Transmembrane protein 173Homo sapiens (human)
Cyclic GMP-AMP synthasecGAMP synthase; cGAS; h-cGAS; EC 2.7.7.86; 2'3'-cGAMP synthase; Mab-21 domain-containing protein 1Homo sapiens (human)
2-5A-dependent ribonuclease2-5A-dependent RNase; EC 3.1.26.-; Ribonuclease 4; Ribonuclease L; RNase LHomo sapiens (human)
2'-5'-oligoadenylate synthase 1(2-5')oligo(A) synthase 1; 2-5A synthase 1; EC 2.7.7.84; E18/E16; p46/p42 OASHomo sapiens (human)
Antiviral innate immune response receptor RIG-IDEAD box protein 58; Probable ATP-dependent RNA helicase DDX58; 3.6.4.13; RIG-I-like receptor 1; RLR-1; Retinoic acid-inducible gene 1 protein; RIG-1; Retinoic acid-inducible gene I protein; RIG-IHomo sapiens (human)
Ribonuclease T2EC 4.6.1.19; Ribonuclease 6Homo sapiens (human)
Ribonuclease H2 subunit ARNase H2 subunit A; EC 3.1.26.4; Aicardi-Goutieres syndrome 4 protein; AGS4; RNase H(35); Ribonuclease HI large subunit; RNase HI large subunit; Ribonuclease HI subunit AHomo sapiens (human)
Double-stranded RNA-specific adenosine deaminaseDRADA; EC 3.5.4.37; 136 kDa double-stranded RNA-binding protein; p136; Interferon-inducible protein 4; IFI-4; K88DSRBPHomo sapiens (human)
Ribonuclease H2 subunit BRNase H2 subunit B; Aicardi-Goutieres syndrome 2 protein; AGS2; Deleted in lymphocytic leukemia 8; Ribonuclease HI subunit BHomo sapiens (human)
Ribonuclease H2 subunit CRNase H2 subunit C; Aicardi-Goutieres syndrome 3 protein; AGS3; RNase H1 small subunit; Ribonuclease HI subunit CHomo sapiens (human)

Compounds (0)

CompoundDescription