Page last updated: 2024-10-06

PLC beta signaling ( GPCR signaling (G alpha q) )

Proteins (3)

ProteinSynonymsTaxonomy
Inositol 1,4,5-trisphosphate receptor type 3IP3 receptor isoform 3; IP3R 3; InsP3R3; Type 3 inositol 1,4,5-trisphosphate receptor; Type 3 InsP3 receptorRattus norvegicus (Norway rat)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2EC 3.1.4.11; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2Rattus norvegicus (Norway rat)
Guanine nucleotide-binding protein G(q) subunit alphaGuanine nucleotide-binding protein alpha-qRattus norvegicus (Norway rat)

Compounds (3)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
guanosine triphosphateGuanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety.
inositol 1,4,5-trisphosphateIntracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.