Page last updated: 2024-10-06

PKMTs methylate histone lysines

Proteins (14)

ProteinSynonymsTaxonomy
N-lysine methyltransferase SETD6EC 2.1.1.-; SET domain-containing protein 6Homo sapiens (human)
Transcription factor p65Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Homo sapiens (human)
Histone-lysine N-methyltransferase, H3 lysine-79 specificEC 2.1.1.360; DOT1-like protein; Histone H3-K79 methyltransferase; H3-K79-HMTase; Lysine N-methyltransferase 4Homo sapiens (human)
Histone-lysine N-methyltransferase EHMT2EC 2.1.1.-; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Lysine N-methyltransferase 1C; Protein G9aHomo sapiens (human)
Histone-lysine N-methyltransferase EHMT1EC 2.1.1.-; Euchromatic histone-lysine N-methyltransferase 1; Eu-HMTase1; G9a-like protein 1; GLP; GLP1; Histone H3-K9 methyltransferase 5; H3-K9-HMTase 5; Lysine N-methyltransferase 1DHomo sapiens (human)
Histone-lysine N-methyltransferase SETD2EC 2.1.1.359; HIF-1; Huntingtin yeast partner B; Huntingtin-interacting protein 1; HIP-1; Huntingtin-interacting protein B; Lysine N-methyltransferase 3A; Protein-lysine N-methyltransferase SETD2; 2.1.1.-; SET domain-containing protein 2; hSET2; p231HBPHomo sapiens (human)
Polycomb protein EEDhEED; Embryonic ectoderm development protein; WD protein associating with integrin cytoplasmic tails 1; WAIT-1Homo sapiens (human)
Histone H4Homo sapiens (human)
Histone-lysine N-methyltransferase EZH2EC 2.1.1.356; ENX-1; Enhancer of zeste homolog 2; Lysine N-methyltransferase 6Homo sapiens (human)
Zinc finger protein AEBP2Adipocyte enhancer-binding protein 2; AE-binding protein 2Homo sapiens (human)
Polycomb protein SUZ12Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homologHomo sapiens (human)
Histone-lysine N-methyltransferase SETDB1EC 2.1.1.366; ERG-associated protein with SET domain; ESET; Histone H3-K9 methyltransferase 4; H3-K9-HMTase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1Homo sapiens (human)
N-lysine methyltransferase KMT5AEC 2.1.1.-; H4-K20-HMTase KMT5A; Histone-lysine N-methyltransferase KMT5A; 2.1.1.361; Lysine N-methyltransferase 5A; Lysine-specific methylase 5A; PR/SET domain-containing protein 07; PR-Set7; PR/SET07; SET domain-containing protein 8Homo sapiens (human)
Activating transcription factor 7-interacting protein 1ATF-interacting protein; ATF-IP; ATF7-interacting protein; ATFa-associated modulator; hAM; MBD1-containing chromatin-associated factor 1; P621Homo sapiens (human)

Compounds (1)

CompoundDescription
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)