PI5P Regulates TP53 Acetylation

Proteins (9)

Protein	Synonyms	Taxonomy
Cellular tumor antigen p53	Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53	Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 6	MAP kinase kinase 6; MAPKK 6; EC 2.7.12.2; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3	Homo sapiens (human)
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	EC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; PI(5)P 4-kinase type II beta; PIP4KII-beta; PtdIns(5)P-4-kinase isoform 2-beta	Homo sapiens (human)
Histone acetyltransferase p300	p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-	Homo sapiens (human)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	EC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; PIP5KIII; Phosphatidylinositol 5-Phosphate 4-Kinase; PI5P4Kalpha; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PI(5)P 4-kinase type II alpha;	Homo sapiens (human)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	EC 5.2.1.8; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1	Homo sapiens (human)
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	EC 2.7.1.149; Phosphatidylinositol 5-phosphate 4-kinase type II gamma; PI(5)P 4-kinase type II gamma; PIP4KII-gamma	Homo sapiens (human)
Inhibitor of growth protein 2	Inhibitor of growth 1-like protein; ING1Lp; p32; p33ING2	Homo sapiens (human)
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase	Type 1 PtdIns-4,5-P2 4-Ptase; EC 3.1.3.78; PtdIns-4,5-P2 4-Ptase I; Transmembrane protein 55B	Homo sapiens (human)

Compounds (6)

Compound	Description
Orthophosphate
adenosine diphosphate	Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Water	A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Coenzyme A
Acetyl Coenzyme A	Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.