Page last updated: 2024-10-06

Oxidative demethylation of DNA

Proteins (4)

ProteinSynonymsTaxonomy
Methylcytosine dioxygenase TET3EC 1.14.11.n2Homo sapiens (human)
Methylcytosine dioxygenase TET1EC 1.14.11.n2; CXXC-type zinc finger protein 6; Leukemia-associated protein with a CXXC domain; Ten-eleven translocation 1 gene proteinHomo sapiens (human)
Methylcytosine dioxygenase TET2EC 1.14.11.n2Homo sapiens (human)
G/T mismatch-specific thymine DNA glycosylaseEC 3.2.2.29; Thymine-DNA glycosylase; hTDGHomo sapiens (human)

Compounds (8)

CompoundDescription
Succinate
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
5-formylcytosinestructure in first source
alpha-Ketoglutarate
sofosbuvirA uridine monophosphate analog inhibitor of HEPATITIS C VIRUS (HCV) polymerase NS5B that is used as an ANTIVIRAL AGENT in the treatment of CHRONIC HEPATITIS C.