Page last updated: 2024-10-06

O-antigen building blocks biosynthesis (E. coli)

Proteins (9)

ProteinSynonymsTaxonomy
UDP-galactopyranose mutaseUGM; EC 5.4.99.9; UDP-GALP mutase; Uridine 5-diphosphate galactopyranose mutaseEscherichia coli K-12
Bifunctional protein GlmUEscherichia coli K-12
Glucose-6-phosphate isomeraseGPI; EC 5.3.1.9; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHIEscherichia coli K-12
Phosphoglucosamine mutaseEC 5.4.2.10Escherichia coli K-12
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]EC 2.6.1.16; D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine--D-fructose-6-phosphate amidotransferaseEscherichia coli K-12
Glucose-1-phosphate thymidylyltransferase 1G1P-TT 1; EC 2.7.7.24; dTDP-glucose pyrophosphorylase 1; dTDP-glucose synthase 1Escherichia coli K-12
dTDP-4-dehydrorhamnose 3,5-epimeraseEC 5.1.3.13; Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthaseEscherichia coli K-12
dTDP-glucose 4,6-dehydratase 1EC 4.2.1.46Escherichia coli K-12
Glucose-1-phosphate thymidylyltransferase 2G1P-TT 2; EC 2.7.7.24; dTDP-glucose pyrophosphorylase 2; dTDP-glucose synthase 2Escherichia coli K-12

Compounds (23)

CompoundDescription
diphosphoric acid
hydronium ion
Uridine TriphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
iodoacetamideAn alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate.
thymidine 5'-triphosphateRN given refers to parent cpd
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
diethyl pyrocarbonatePreservative for wines, soft drinks, and fruit juices and a gentle esterifying agent.
ethylmaleimideA sulfhydryl reagent that is widely used in experimental biochemical studies.
glucosamine 6-phosphateRN given refers to parent cpd
glutamate
Glucose-6-PhosphateAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
polyglutamineRN given for (D)-isomer
glucose-1-phosphateRN given refers to (alpha-D-Glc)-isomer
uridine diphosphate n-acetylmuramic acidA nucleoside diphosphate sugar which is formed from UDP-N-acetylglucosamine and phosphoenolpyruvate. It serves as the building block upon which peptidoglycan is formed.
Coenzyme A
deoxythymidine diphosphate-glucosestructure given in first source
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
2-deoxy-2-aminoglucitol-6-phosphateinhibits glucosamine 6-phosphate deaminase