Page last updated: 2024-10-06

Nucleotide Excision Repair

Proteins (84)

ProteinSynonymsTaxonomy
Small ubiquitin-related modifier 2SUMO-2; HSMT3; SMT3 homolog 2; SUMO-3; Sentrin-2; Ubiquitin-like protein SMT3B; Smt3BHomo sapiens (human)
E3 ubiquitin-protein ligase RBX1EC 2.3.2.27; EC 2.3.2.32; E3 ubiquitin-protein transferase RBX1; Protein ZYP; RING finger protein 75; RING-box protein 1; Rbx1; Regulator of cullins 1; ROC1Homo sapiens (human)
Small ubiquitin-related modifier 1SUMO-1; GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Smt3C; Ubiquitin-like protein UBL1Homo sapiens (human)
DNA damage-binding protein 1DDB p127 subunit; DNA damage-binding protein a; DDBa; Damage-specific DNA-binding protein 1; HBV X-associated protein 1; XAP-1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; XPE-binding factor; XPE-BF; Xeroderma pigmentosum grHomo sapiens (human)
COP9 signalosome complex subunit 5SGN5; Signalosome subunit 5; EC 3.4.-.-; Jun activation domain-binding protein 1Homo sapiens (human)
Cyclin-dependent kinase 7EC 2.7.11.22; EC 2.7.11.23; 39 kDa protein kinase; p39 Mo15; CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunitHomo sapiens (human)
Cyclin-HMO15-associated protein; p34; p37Homo sapiens (human)
General transcription and DNA repair factor IIH helicase subunit XPBTFIIH subunit XPB; EC 3.6.4.12; Basic transcription factor 2 89 kDa subunit; BTF2 p89; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; TFIIH basal transcription factor complex 89 kDa subunit; TFIIH 89 kDa subunit; TFIIH p8Homo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 45EC 3.4.19.12; Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45Homo sapiens (human)
Replication protein A 70 kDa DNA-binding subunitRP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding proteinHomo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
DNA excision repair protein ERCC-1Homo sapiens (human)
DNA repair protein complementing XP-A cellsXeroderma pigmentosum group A-complementing proteinHomo sapiens (human)
Replication factor C subunit 5Activator 1 36 kDa subunit; A1 36 kDa subunit; Activator 1 subunit 5; Replication factor C 36 kDa subunit; RF-C 36 kDa subunit; RFC36Homo sapiens (human)
DNA repair protein complementing XP-G cellsEC 3.1.-.-; DNA excision repair protein ERCC-5; Xeroderma pigmentosum group G-complementing proteinHomo sapiens (human)
Proliferating cell nuclear antigenPCNA; CyclinHomo sapiens (human)
Actin, cytoplasmic 1Beta-actinHomo sapiens (human)
Ubiquitin-conjugating enzyme E2 NEC 2.3.2.23; Bendless-like ubiquitin-conjugating enzyme; E2 ubiquitin-conjugating enzyme N; Ubc13; UbcH13; Ubiquitin carrier protein N; Ubiquitin-protein ligase NHomo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 7EC 3.4.19.12; Deubiquitinating enzyme 7; Herpesvirus-associated ubiquitin-specific protease; Ubiquitin thioesterase 7; Ubiquitin-specific-processing protease 7Homo sapiens (human)
RuvB-like 1EC 3.6.4.12; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alHomo sapiens (human)
General transcription and DNA repair factor IIH helicase subunit XPDTFIIH subunit XPD; EC 3.6.4.12; Basic transcription factor 2 80 kDa subunit; BTF2 p80; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH 80 kDa subunit; TFHomo sapiens (human)
CDK-activating kinase assembly factor MAT1CDK7/cyclin-H assembly factor; Cyclin-G1-interacting protein; Menage a trois; RING finger protein 66; RING finger protein MAT1; p35; p36Homo sapiens (human)
SUMO-conjugating enzyme UBC9EC 2.3.2.-; RING-type E3 SUMO transferase UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-protein ligase I; p18Homo sapiens (human)
DNA repair endonuclease XPFEC 3.1.-.-; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing proteinHomo sapiens (human)
COP9 signalosome complex subunit 8SGN8; Signalosome subunit 8; COP9 homolog; hCOP9; JAB1-containing signalosome subunit 8Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB1RNA polymerase II subunit B1; EC 2.7.7.6; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1; 2.7.7.48Homo sapiens (human)
Small ubiquitin-related modifier 3SUMO-3; SMT3 homolog 1; SUMO-2; Ubiquitin-like protein SMT3A; Smt3AHomo sapiens (human)
RNA polymerase II elongation factor ELLEleven-nineteen lysine-rich leukemia proteinHomo sapiens (human)
COP9 signalosome complex subunit 1SGN1; Signalosome subunit 1; G protein pathway suppressor 1; GPS-1; JAB1-containing signalosome subunit 1; Protein MFHHomo sapiens (human)
Actin-related protein 5hARP5; Sarcoma antigen NY-SAR-16Homo sapiens (human)
COP9 signalosome complex subunit 4SGN4; Signalosome subunit 4; JAB1-containing signalosome subunit 4Homo sapiens (human)
Transcriptional repressor protein YY1Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and yang 1; YY-1Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC4RNA polymerases I, II, and III subunit ABC4; ABC10-alpha; DNA-directed RNA polymerase II subunit K; RNA polymerase II 7.0 kDa subunit; RPB7.0; RPB10alphaHomo sapiens (human)
E3 ubiquitin-protein ligase ArkadiaEC 2.3.2.27; RING finger protein 111; hRNF111; RING-type E3 ubiquitin transferase ArkadiaHomo sapiens (human)
Pre-mRNA-processing factor 19EC 2.3.2.27; Nuclear matrix protein 200; PRP19/PSO4 homolog; hPso4; RING-type E3 ubiquitin transferase PRP19; Senescence evasion factorHomo sapiens (human)
DNA-directed RNA polymerase II subunit RPB4RNA polymerase II subunit B4; DNA-directed RNA polymerase II subunit D; RNA polymerase II 16 kDa subunit; RPB16Homo sapiens (human)
RNA helicase aquariusEC 3.6.4.13; Intron-binding protein of 160 kDa; IBP160Homo sapiens (human)
Actin-like protein 6A53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit KHomo sapiens (human)
Non-histone chromosomal protein HMG-14High mobility group nucleosome-binding domain-containing protein 1Homo sapiens (human)
TCF3 fusion partnerINO80 complex subunit F; Protein FB1Homo sapiens (human)
Replication protein A 32 kDa subunitRP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB3RNA polymerase II subunit 3; RNA polymerase II subunit B3; DNA-directed RNA polymerase II 33 kDa polypeptide; RPB33; DNA-directed RNA polymerase II subunit C; RPB31Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC1RNA polymerases I, II, and III subunit ABC1; DNA-directed RNA polymerase II 23 kDa polypeptide; DNA-directed RNA polymerase II subunit E; RPB5 homolog; XAP4Homo sapiens (human)
Transcription elongation factor A protein 1Transcription elongation factor S-II protein 1; Transcription elongation factor TFIIS.oHomo sapiens (human)
DNA-directed RNA polymerase II subunit RPB2EC 2.7.7.6; DNA-directed RNA polymerase II 140 kDa polypeptide; DNA-directed RNA polymerase II subunit B; RNA polymerase II subunit 2; RNA polymerase II subunit B2Homo sapiens (human)
General transcription factor IIH subunit 1Basic transcription factor 2 62 kDa subunit; BTF2 p62; General transcription factor IIH polypeptide 1; TFIIH basal transcription factor complex p62 subunitHomo sapiens (human)
Replication protein A 14 kDa subunitRP-A p14; Replication factor A protein 3; RF-A protein 3Homo sapiens (human)
Replication factor C subunit 4Activator 1 37 kDa subunit; A1 37 kDa subunit; Activator 1 subunit 4; Replication factor C 37 kDa subunit; RF-C 37 kDa subunit; RFC37Homo sapiens (human)
Replication factor C subunit 2Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40Homo sapiens (human)
Replication factor C subunit 1Activator 1 140 kDa subunit; A1 140 kDa subunit; Activator 1 large subunit; Activator 1 subunit 1; DNA-binding protein PO-GA; Replication factor C 140 kDa subunit; RF-C 140 kDa subunit; RFC140; Replication factor C large subunitHomo sapiens (human)
DNA-directed RNA polymerase II subunit RPB9RNA polymerase II subunit B9; DNA-directed RNA polymerase II subunit I; RNA polymerase II 14.5 kDa subunit; RPB14.5Homo sapiens (human)
Replication factor C subunit 3Activator 1 38 kDa subunit; A1 38 kDa subunit; Activator 1 subunit 3; Replication factor C 38 kDa subunit; RF-C 38 kDa subunit; RFC38Homo sapiens (human)
Centrin-2Caltractin isoform 1Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC3RNA polymerases I, II, and III subunit ABC3; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide; RPB17; RPB8 homolog; hRPB8Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB11-aRNA polymerase II subunit B11-a; RPB11a; DNA-directed RNA polymerase II subunit J-1; RNA polymerase II 13.3 kDa subunitHomo sapiens (human)
COP9 signalosome complex subunit 2SGN2; Signalosome subunit 2; Alien homolog; JAB1-containing signalosome subunit 2; Thyroid receptor-interacting protein 15; TR-interacting protein 15; TRIP-15Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC2RNA polymerases I, II, and III subunit ABC2; DNA-directed RNA polymerase II subunit F; DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide; RPABC14.4; RPB14.4; RPB6 homolog; RPC15Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB7RNA polymerase II subunit B7; DNA-directed RNA polymerase II subunit G; RNA polymerase II 19 kDa subunit; RPB19Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC5RNA polymerases I, II, and III subunit ABC5; DNA-directed RNA polymerase III subunit L; RNA polymerase II 7.6 kDa subunit; RPB7.6; RPB10 homologHomo sapiens (human)
DNA repair protein complementing XP-C cellsXeroderma pigmentosum group C-complementing protein; p125Homo sapiens (human)
DNA excision repair protein ERCC-6EC 3.6.4.-; ATP-dependent helicase ERCC6; Cockayne syndrome protein CSBHomo sapiens (human)
DNA excision repair protein ERCC-8Cockayne syndrome WD repeat protein CSAHomo sapiens (human)
General transcription factor IIH subunit 2Basic transcription factor 2 44 kDa subunit; BTF2 p44; General transcription factor IIH polypeptide 2; TFIIH basal transcription factor complex p44 subunitHomo sapiens (human)
General transcription factor IIH subunit 3Basic transcription factor 2 34 kDa subunit; BTF2 p34; General transcription factor IIH polypeptide 3; TFIIH basal transcription factor complex p34 subunitHomo sapiens (human)
Ubiquitin-conjugating enzyme E2 variant 2DDVit 1; Enterocyte differentiation-associated factor 1; EDAF-1; Enterocyte differentiation-promoting factor 1; EDPF-1; MMS2 homolog; Vitamin D3-inducible proteinHomo sapiens (human)
UV-stimulated scaffold protein AHomo sapiens (human)
INO80 complex subunit DHomo sapiens (human)
Nuclear factor related to kappa-B-binding proteinDNA-binding protein R kappa-B; INO80 complex subunit GHomo sapiens (human)
INO80 complex subunit CIES6 homolog; hIes6Homo sapiens (human)
General transcription factor IIH subunit 5General transcription factor IIH polypeptide 5; TFB5 ortholog; TFIIH basal transcription factor complex TTD-A subunitHomo sapiens (human)
COP9 signalosome complex subunit 6SGN6; Signalosome subunit 6; JAB1-containing signalosome subunit 6; MOV34 homolog; Vpr-interacting protein; hVIPHomo sapiens (human)
Chromodomain-helicase-DNA-binding protein 1-likeEC 3.6.4.12; Amplified in liver cancer protein 1Homo sapiens (human)
INO80 complex subunit ECoiled-coil domain-containing protein 95Homo sapiens (human)
DNA damage-binding protein 2DDB p48 subunit; DDBb; Damage-specific DNA-binding protein 2; UV-damaged DNA-binding protein 2; UV-DDB 2Homo sapiens (human)
General transcription factor IIH subunit 4Basic transcription factor 2 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4; TFIIH basal transcription factor complex p52 subunitHomo sapiens (human)
Microspherule protein 158 kDa microspherule protein; Cell cycle-regulated factor p78; INO80 complex subunit J; MCRS2Homo sapiens (human)
Zinc finger protein 830Coiled-coil domain-containing protein 16Homo sapiens (human)
INO80 complex subunit BHigh mobility group AT-hook 1-like 4; IES2 homolog; hIes2; PAP-1-associated protein 1; PAPA-1; Zinc finger HIT domain-containing protein 4Homo sapiens (human)
Actin-related protein 8hArp8; INO80 complex subunit NHomo sapiens (human)
Pre-mRNA-splicing factor SYF1Protein HCNP; XPA-binding protein 2Homo sapiens (human)
Chromatin-remodeling ATPase INO80hINO80; EC 3.6.4.-; DNA helicase-related INO80 complex homolog 1; DNA helicase-related protein INO80; INO80 complex subunit AHomo sapiens (human)
Pre-mRNA-splicing factor ISY1 homologHomo sapiens (human)
Peptidyl-prolyl cis-trans isomerase EPPIase E; EC 5.2.1.8; Cyclophilin E; Cyclophilin-33; Rotamase EHomo sapiens (human)
COP9 signalosome complex subunit 3SGN3; Signalosome subunit 3; JAB1-containing signalosome subunit 3Homo sapiens (human)

Compounds (6)

CompoundDescription
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
niacinamideAn important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.