Page last updated: 2024-10-06

NoRC negatively regulates rRNA expression

Proteins (42)

ProteinSynonymsTaxonomy
Methyl-CpG-binding domain protein 2Demethylase; DMTase; Methyl-CpG-binding protein MBD2Homo sapiens (human)
Histone deacetylase 1HD1; EC 3.5.1.98Homo sapiens (human)
Histone deacetylase 2HD2; EC 3.5.1.98Homo sapiens (human)
General transcription and DNA repair factor IIH helicase subunit XPBTFIIH subunit XPB; EC 3.6.4.12; Basic transcription factor 2 89 kDa subunit; BTF2 p89; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; TFIIH basal transcription factor complex 89 kDa subunit; TFIIH 89 kDa subunit; TFIIH p8Homo sapiens (human)
DNA (cytosine-5)-methyltransferase 1Dnmt1; EC 2.1.1.37; CXXC-type zinc finger protein 9; DNA methyltransferase HsaI; DNA MTase HsaI; M.HsaI; MCMTHomo sapiens (human)
DNA (cytosine-5)-methyltransferase 3BDnmt3b; EC 2.1.1.37; DNA methyltransferase HsaIIIB; DNA MTase HsaIIIB; M.HsaIIIBHomo sapiens (human)
TATA box-binding protein-associated factor RNA polymerase I subunit ARNA polymerase I-specific TBP-associated factor 48 kDa; TAFI48; TATA box-binding protein-associated factor 1A; TBP-associated factor 1A; Transcription factor SL1; Transcription initiation factor SL1/TIF-IB subunit AHomo sapiens (human)
Histone H4Homo sapiens (human)
Bromodomain adjacent to zinc finger domain protein 2ATranscription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3Homo sapiens (human)
General transcription and DNA repair factor IIH helicase subunit XPDTFIIH subunit XPD; EC 3.6.4.12; Basic transcription factor 2 80 kDa subunit; BTF2 p80; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH 80 kDa subunit; TFHomo sapiens (human)
DNA-directed RNA polymerase I subunit RPA1RNA polymerase I subunit A1; EC 2.7.7.6; A190; DNA-directed RNA polymerase I largest subunit; DNA-directed RNA polymerase I subunit A; RNA polymerase I 194 kDa subunit; RPA194Homo sapiens (human)
Histone deacetylase complex subunit SAP130130 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p130Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC4RNA polymerases I, II, and III subunit ABC4; ABC10-alpha; DNA-directed RNA polymerase II subunit K; RNA polymerase II 7.0 kDa subunit; RPB7.0; RPB10alphaHomo sapiens (human)
Histone deacetylase complex subunit SAP1818 kDa Sin3-associated polypeptide; 2HOR0202; Cell growth-inhibiting gene 38 protein; Sin3-associated polypeptide p18Homo sapiens (human)
DNA-directed RNA polymerases I and III subunit RPAC1DNA-directed RNA polymerase I subunit C; RNA polymerases I and III subunit AC1; AC40; DNA-directed RNA polymerases I and III 40 kDa polypeptide; RPA40; RPA39; RPC40Homo sapiens (human)
DNA-directed RNA polymerase I subunit RPA34A34.5; Antisense to ERCC-1 protein; ASE-1; CD3-epsilon-associated protein; CD3E-associated protein; DNA-directed RNA polymerase I subunit G; RNA polymerase I-associated factor PAF49Homo sapiens (human)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5; EC 3.6.4.-; Sucrose nonfermenting protein 2 homolog; hSNF2HHomo sapiens (human)
Histone deacetylase complex subunit SAP3030 kDa Sin3-associated polypeptide; Sin3 corepressor complex subunit SAP30; Sin3-associated polypeptide p30Homo sapiens (human)
Nucleolar transcription factor 1Autoantigen NOR-90; Upstream-binding factor 1; UBF-1Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC1RNA polymerases I, II, and III subunit ABC1; DNA-directed RNA polymerase II 23 kDa polypeptide; DNA-directed RNA polymerase II subunit E; RPB5 homolog; XAP4Homo sapiens (human)
TATA-box-binding proteinTATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunitHomo sapiens (human)
General transcription factor IIH subunit 1Basic transcription factor 2 62 kDa subunit; BTF2 p62; General transcription factor IIH polypeptide 1; TFIIH basal transcription factor complex p62 subunitHomo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC3RNA polymerases I, II, and III subunit ABC3; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide; RPB17; RPB8 homolog; hRPB8Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC2RNA polymerases I, II, and III subunit ABC2; DNA-directed RNA polymerase II subunit F; DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide; RPABC14.4; RPB14.4; RPB6 homolog; RPC15Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC5RNA polymerases I, II, and III subunit ABC5; DNA-directed RNA polymerase III subunit L; RNA polymerase II 7.6 kDa subunit; RPB7.6; RPB10 homologHomo sapiens (human)
General transcription factor IIH subunit 2Basic transcription factor 2 44 kDa subunit; BTF2 p44; General transcription factor IIH polypeptide 2; TFIIH basal transcription factor complex p44 subunitHomo sapiens (human)
General transcription factor IIH subunit 3Basic transcription factor 2 34 kDa subunit; BTF2 p34; General transcription factor IIH polypeptide 3; TFIIH basal transcription factor complex p34 subunitHomo sapiens (human)
Transcription termination factor 1TTF-1; RNA polymerase I termination factor; Transcription termination factor I; TTF-IHomo sapiens (human)
TATA box-binding protein-associated factor RNA polymerase I subunit CRNA polymerase I-specific TBP-associated factor 110 kDa; TAFI110; TATA box-binding protein-associated factor 1C; TBP-associated factor 1C; Transcription initiation factor SL1/TIF-IB subunit CHomo sapiens (human)
DNA-directed RNA polymerase I subunit RPA43DNA-directed RNA polymerase I subunit F; Twist neighbor proteinHomo sapiens (human)
AT-rich interactive domain-containing protein 4BARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Breast cancer-associated antigen BRCAA1; Histone deacetylase complex subunit SAP180; Retinoblastoma-binding protein 1-like 1Homo sapiens (human)
TATA box-binding protein-associated factor RNA polymerase I subunit BRNA polymerase I-specific TBP-associated factor 63 kDa; TAFI63; TATA box-binding protein-associated factor 1B; TBP-associated factor 1B; Transcription initiation factor SL1/TIF-IB subunit BHomo sapiens (human)
General transcription factor IIH subunit 5General transcription factor IIH polypeptide 5; TFB5 ortholog; TFIIH basal transcription factor complex TTD-A subunitHomo sapiens (human)
General transcription factor IIH subunit 4Basic transcription factor 2 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4; TFIIH basal transcription factor complex p52 subunitHomo sapiens (human)
DNA-directed RNA polymerase I subunit RPA49RNA polymerase I subunit A49; DNA-directed RNA polymerase I subunit E; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53Homo sapiens (human)
TATA box-binding protein-associated factor RNA polymerase I subunit DRNA polymerase I-specific TBP-associated factor 41 kDa; TAFI41; TATA box-binding protein-associated factor 1D; TBP-associated factor 1D; Transcription initiation factor SL1/TIF-IB subunit DHomo sapiens (human)
Sin3 histone deacetylase corepressor complex component SDS345 kDa Sin3-associated polypeptide; Suppressor of defective silencing 3 protein homologHomo sapiens (human)
DNA-directed RNA polymerase I subunit RPA2RNA polymerase I subunit 2; EC 2.7.7.6; DNA-directed RNA polymerase I 135 kDa polypeptide; RPA135Homo sapiens (human)
Histone deacetylase complex subunit SAP30LHCV non-structural protein 4A-transactivated protein 2; Sin3 corepressor complex subunit SAP30L; Sin3-associated protein p30-likeHomo sapiens (human)
DNA-directed RNA polymerase I subunit RPA12DNA-directed RNA polymerase I subunit H; Zinc ribbon domain-containing protein 1Homo sapiens (human)
SAP30-binding proteinTranscriptional regulator protein HCNGPHomo sapiens (human)
Protein POLR1D, isoform 2Homo sapiens (human)

Compounds (2)

CompoundDescription
acetic acidProduct of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)