| Compound | Description |
|---|
| nicotine | Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke. |
| nornicotine | agricultural or horticultural insecticide; RN given refers to (+-)-isomer; structure |
| nicotine n-glucuronide | a metabolite of nicotine |
| cotinine N-glucuronide | structure given in first source; a major urinary metabolite of nicotine |
| Cotinine | The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties. |
| nicotine 1-n-oxide | RN given refers to unspecified stereoisomer |
| nicotine imine | RN given refers to 11C-labeled (S)-isomer |
| cotinine-N-oxide | metabolite of nicotine; structure |