| pyridoxal phosphate | This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE). |
| Dopamine Hydrochloride | |
| 5-hydroxytryptophan | The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. |
| tryptophan | An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals. |
| melatonin | A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. |
| 4a-carbinolamine tetrahydrobiopterin | structure given in first source |
| vanillactic acid | metabolite of catecholamines |
| 3-methoxytyramine | RN given refers to parent cpd |
| homovanillic acid | A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid. |
| hydroxyindoleacetic acid | |
| metanephrine | Product of epinephrine O-methylation. It is a commonly occurring, pharmacologically and physiologically inactive metabolite of epinephrine. |
| Serotonin | A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator. |
| 3,4-dihydroxyphenylacetic acid | A deaminated metabolite of LEVODOPA. |
| hydroxyindoleacetaldehyde | |
| 3-methoxytyrosine | |