Page last updated: 2024-10-06

NOTCH3 Activation and Transmission of Signal to the Nucleus

Proteins (13)

ProteinSynonymsTaxonomy
Epidermal growth factor receptorEC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1Homo sapiens (human)
NicastrinHomo sapiens (human)
Gamma-secretase subunit PEN-2Presenilin enhancer protein 2Homo sapiens (human)
Neurogenic locus notch homolog protein 3Notch 3Homo sapiens (human)
Protein jagged-2Jagged2; hJ2Homo sapiens (human)
Disintegrin and metalloproteinase domain-containing protein 10ADAM 10; EC 3.4.24.81; CDw156; Kuzbanian protein homolog; Mammalian disintegrin-metalloproteaseHomo sapiens (human)
Pro-epidermal growth factorEGFHomo sapiens (human)
Protein jagged-1Jagged1; hJ1Homo sapiens (human)
NEDD4-like E3 ubiquitin-protein ligase WWP2EC 2.3.2.26; Atrophin-1-interacting protein 2; AIP2; HECT-type E3 ubiquitin transferase WWP2; WW domain-containing protein 2Homo sapiens (human)
Y-box-binding protein 1YB-1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Nuclease-sensitive element-binding protein 1; Y-box transcription factorHomo sapiens (human)
Delta-like protein 1Drosophila Delta homolog 1; Delta1; H-Delta-1Homo sapiens (human)
Delta-like protein 4Drosophila Delta homolog 4; Delta4Homo sapiens (human)
Transforming acidic coiled-coil-containing protein 3ERIC-1Homo sapiens (human)

Compounds (3)

CompoundDescription
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.