Page last updated: 2024-10-06
NAD salvage pathway
Proteins (11)
| Protein | Synonyms | Taxonomy |
|---|---|---|
| NAD-dependent protein deacetylase HST2 | EC 2.3.1.286; Homologous to SIR2 protein 2; Regulatory protein SIR2 homolog 2 | Saccharomyces cerevisiae S288C |
| Nicotinamidase | EC 3.5.1.19; Nicotinamide deamidase; NAMase | Saccharomyces cerevisiae S288C |
| Nicotinate phosphoribosyltransferase | NAPRTase; EC 6.3.4.21 | Saccharomyces cerevisiae S288C |
| NAD-dependent histone deacetylase SIR2 | EC 2.3.1.286; Regulatory protein SIR2; Silent information regulator 2 | Saccharomyces cerevisiae S288C |
| Glutamine-dependent NAD(+) synthetase | EC 6.3.5.1; NAD(+) synthase [glutamine-hydrolyzing] | Saccharomyces cerevisiae S288C |
| Probable amidase | EC 3.5.1.4 | Saccharomyces cerevisiae S288C |
| Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 | NMN/NaMN adenylyltransferase 2; EC 2.7.7.1; EC 2.7.7.18; NAD(+) diphosphorylase 2; NAD(+) pyrophosphorylase 2; Nicotinamide-nucleotide adenylyltransferase 2; NMN adenylyltransferase 2; NMNAT 2; Nicotinate-nucleotide adenylyltransferase 2; NaMN adenylyltra | Saccharomyces cerevisiae S288C |
| NAD-dependent protein deacetylase HST1 | EC 2.3.1.286; Homologous to SIR2 protein 1; Regulatory protein SIR2 homolog 1 | Saccharomyces cerevisiae S288C |
| NAD-dependent histone deacetylase HST3 | EC 2.3.1.286; Homologous to SIR2 protein 3; Regulatory protein SIR2 homolog 3 | Saccharomyces cerevisiae S288C |
| NAD-dependent histone deacetylase HST4 | EC 2.3.1.286; Homologous to SIR2 protein 4; Regulatory protein SIR2 homolog 4 | Saccharomyces cerevisiae S288C |
| Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | NMN/NaMN adenylyltransferase 1; EC 2.7.7.1; EC 2.7.7.18; NAD(+) diphosphorylase 1; NAD(+) pyrophosphorylase 1; Nicotinamide-nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; NMNAT 1; Nicotinate-nucleotide adenylyltransferase 1; NaMN adenylyltra | Saccharomyces cerevisiae S288C |
Compounds (17)
| Compound | Description |
|---|---|
| diphosphoric acid | |
| hydronium ion | |
| Ammonium | |
| Mercury | A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing. |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Nickel | A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE. |
| niacinamide | An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. |
| Nico-400 | |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| glutamate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| polyglutamine | RN given for (D)-isomer |
| nicotinic acid adenine dinucleotide | intermediate in the biosynthesis of NAD |
| nicotinate mononucleotide |