Page last updated: 2024-10-06

N-glycan trimming in the ER and Calnexin/Calreticulin cycle

Proteins (18)

ProteinSynonymsTaxonomy
Mannosyl-oligosaccharide glucosidaseEC 3.2.1.106; Processing A-glucosidase IHomo sapiens (human)
Protein disulfide-isomerase A3EC 5.3.4.1; 58 kDa glucose-regulated protein; 58 kDa microsomal protein; p58; Disulfide isomerase ER-60; Endoplasmic reticulum resident protein 57; ER protein 57; ERp57; Endoplasmic reticulum resident protein 60; ER protein 60; ERp60Homo sapiens (human)
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidasePNGase; hPNGase; EC 3.5.1.52; N-glycanase 1; Peptide:N-glycanaseHomo sapiens (human)
Neutral alpha-glucosidase ABEC 3.2.1.207; Alpha-glucosidase 2; Glucosidase II subunit alphaHomo sapiens (human)
Cytosolic endo-beta-N-acetylglucosaminidaseENGase; EC 3.2.1.96Homo sapiens (human)
Glucosidase 2 subunit beta80K-H protein; Glucosidase II subunit beta; Protein kinase C substrate 60.1 kDa protein heavy chain; PKCSHHomo sapiens (human)
Transitional endoplasmic reticulum ATPaseTER ATPase; EC 3.6.4.6; 15S Mg(2+)-ATPase p97 subunit; Valosin-containing protein; VCPHomo sapiens (human)
CalnexinIP90; Major histocompatibility complex class I antigen-binding protein p88; p90Homo sapiens (human)
26S proteasome regulatory subunit 4P26s4; 26S proteasome AAA-ATPase subunit RPT2; Proteasome 26S subunit ATPase 1Homo sapiens (human)
CalreticulinCRP55; Calregulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP; grp60Homo sapiens (human)
Protein OS-9Amplified in osteosarcoma 9Homo sapiens (human)
UV excision repair protein RAD23 homolog BHR23B; hHR23B; XP-C repair-complementing complex 58 kDa protein; p58Homo sapiens (human)
UBX domain-containing protein 1SAPK substrate protein 1; UBA/UBX 33.3 kDa proteinHomo sapiens (human)
MalectinHomo sapiens (human)
Derlin-1Degradation in endoplasmic reticulum protein 1; DERtrin-1; Der1-like protein 1Homo sapiens (human)
Derlin-2Degradation in endoplasmic reticulum protein 2; DERtrin-2; Der1-like protein 2; F-LAN-1; F-LANaHomo sapiens (human)
Protein sel-1 homolog 1Suppressor of lin-12-like protein 1; Sel-1LHomo sapiens (human)
E3 ubiquitin-protein ligase AMFREC 2.3.2.27; Autocrine motility factor receptor; AMF receptor; RING finger protein 45; gp78Homo sapiens (human)

Compounds (4)

CompoundDescription
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
mannoseA hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants. (From Grant & Hackh's Chemical Dictionary, 5th ed & Random House Unabridged Dictionary, 2d ed)
dolichol monophosphate
glucoseA primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.