Page last updated: 2024-10-06

Morphine Metabolism Pathway

Proteins (17)

ProteinSynonymsTaxonomy
Protein disulfide-isomerase A4EC 5.3.4.1; Endoplasmic reticulum resident protein 70; ER protein 70; ERp70; Endoplasmic reticulum resident protein 72; ER protein 72; ERp-72; ERp72Homo sapiens (human)
Mu-type opioid receptorM-OR-1; MOR-1; Mu opiate receptor; Mu opioid receptor; MOP; hMOPHomo sapiens (human)
Protein disulfide-isomerase A2EC 5.3.4.1; Pancreas-specific protein disulfide isomerase; PDIpHomo sapiens (human)
UDP-glucuronosyltransferase 2B4UDPGT 2B4; UGT2B4; EC 2.4.1.17; HLUG25; Hyodeoxycholic acid-specific UDPGT; UDPGTh-1Homo sapiens (human)
Peptidyl-prolyl cis-trans isomerase BPPIase B; EC 5.2.1.8; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLPHomo sapiens (human)
Endoplasmic reticulum chaperone BiPEC 3.6.4.10; 78 kDa glucose-regulated protein; GRP-78; Binding-immunoglobulin protein; BiP; Heat shock protein 70 family protein 5; HSP70 family protein 5; Heat shock protein family A member 5; Immunoglobulin heavy chain-binding proteinHomo sapiens (human)
UDP-glucuronosyltransferase 2B7UDPGT 2B7; UGT2B7; EC 2.4.1.17; 3,4-catechol estrogen-specific UDPGT; UDP-glucuronosyltransferase 2B9; UDPGT 2B9; UDPGTh-2Homo sapiens (human)
UDP-glucuronosyltransferase 1A1 UGT1A1; EC 2.4.1.17; Bilirubin-specific UDPGT isozyme 1; hUG-BR1; UDP-glucuronosyltransferase 1-1; UDPGT 1-1; UGT1*1; UGT1-01; UGT1.1; UDP-glucuronosyltransferase 1A isoform 1Homo sapiens (human)
UDP-glucuronosyltransferase 1A3UGT1A3; EC 2.4.1.17; UDP-glucuronosyltransferase 1-3; UDPGT 1-3; UGT1*3; UGT1-03; UGT1.3; UDP-glucuronosyltransferase 1-C; UGT-1C; UGT1C; UDP-glucuronosyltransferase 1A isoform 3Homo sapiens (human)
UDP-glucuronosyltransferase 2B15UDPGT 2B15; UGT2B15; EC 2.4.1.17; HLUG4; UDP-glucuronosyltransferase 2B8; UDPGT 2B8; UDPGTh-3Homo sapiens (human)
Protein disulfide-isomerase A6EC 5.3.4.1; Endoplasmic reticulum protein 5; ER protein 5; ERp5; Protein disulfide isomerase P5; Thioredoxin domain-containing protein 7Homo sapiens (human)
UDP-glucuronosyltransferase 1A8UGT1A8; EC 2.4.1.17; UDP-glucuronosyltransferase 1-8; UDPGT 1-8; UGT1*8; UGT1-08; UGT1.8; UDP-glucuronosyltransferase 1-H; UGT-1H; UGT1HHomo sapiens (human)
Endoplasmic reticulum resident protein 29ERp29; Endoplasmic reticulum resident protein 28; ERp28; Endoplasmic reticulum resident protein 31; ERp31Homo sapiens (human)
Stromal cell-derived factor 2-like protein 1SDF2-like protein 1; PWP1-interacting protein 8Homo sapiens (human)
DnaJ homolog subfamily B member 11APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-inteHomo sapiens (human)
HYOU1 proteinHomo sapiens (human)
Endoplasmin Homo sapiens (human)

Compounds (5)

CompoundDescription
morphineThe principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
uridine diphosphate glucuronic acidA nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones.
morphine-6-glucuronideRN given refers to (5alpha,6alpha)-isomer
morphine-3-glucuronideRN given refers to (5alpha,6alpha)-isomer