Mitochondrial biogenesis

Proteins (62)

Protein	Synonyms	Taxonomy
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial	EC 2.3.1.-; NAD-dependent ADP-ribosyltransferase sirtuin-4; 2.4.2.-; NAD-dependent protein deacetylase sirtuin-4; 2.3.1.286; Regulatory protein SIR2 homolog 4; SIR2-like protein 4	Homo sapiens (human)
Stress-70 protein, mitochondrial	75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74; PBP74	Homo sapiens (human)
Histone deacetylase 3	HD3; EC 3.5.1.98; RPD3-2; SMAP45	Homo sapiens (human)
F-box-like/WD repeat-containing protein TBL1XR1	Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1	Homo sapiens (human)
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6	Homo sapiens (human)
Retinoic acid receptor RXR-alpha	Nuclear receptor subfamily 2 group B member 1; Retinoid X receptor alpha	Homo sapiens (human)
Calcium/calmodulin-dependent protein kinase type IV	CaMK IV; EC 2.7.11.17; CaM kinase-GR	Homo sapiens (human)
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	hSIRT3; EC 2.3.1.286; Regulatory protein SIR2 homolog 3; SIR2-like protein 3	Homo sapiens (human)
MICOS complex subunit MIC60	Cell proliferation-inducing gene 4/52 protein; Mitochondrial inner membrane protein; Mitofilin; p87/89	Homo sapiens (human)
Cyclic AMP-responsive element-binding protein 1	CREB-1; cAMP-responsive element-binding protein 1	Homo sapiens (human)
Cytochrome c		Homo sapiens (human)
Transcription factor A, mitochondrial	mtTFA; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2	Homo sapiens (human)
Nuclear receptor corepressor 1	N-CoR; N-CoR1	Homo sapiens (human)
ATP synthase subunit beta, mitochondrial	EC 7.1.2.2; ATP synthase F1 subunit beta	Homo sapiens (human)
Calmodulin-1		Homo sapiens (human)
Steroid hormone receptor ERR1	Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1	Homo sapiens (human)
ATP synthase subunit alpha, mitochondrial	ATP synthase F1 subunit alpha	Homo sapiens (human)
5'-AMP-activated protein kinase catalytic subunit alpha-2	AMPK subunit alpha-2; EC 2.7.11.1; Acetyl-CoA carboxylase kinase; ACACA kinase; 2.7.11.27; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; 2.7.11.31	Homo sapiens (human)
NAD-dependent protein deacylase sirtuin-5, mitochondrial	EC 2.3.1.-; Regulatory protein SIR2 homolog 5; SIR2-like protein 5	Homo sapiens (human)
DNA-directed RNA polymerase, mitochondrial	MtRPOL; EC 2.7.7.6	Homo sapiens (human)
Cyclic AMP-dependent transcription factor ATF-2	cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; cAMP response element-binding protein CRE-BP1	Homo sapiens (human)
Host cell factor 1	HCF; HCF-1; C1 factor; CFF; VCAF; VP16 accessory protein	Homo sapiens (human)
ATP synthase subunit gamma, mitochondrial	ATP synthase F1 subunit gamma; F-ATPase gamma subunit	Homo sapiens (human)
MICOS complex subunit MIC10	Mitochondrial inner membrane organizing system protein 1	Homo sapiens (human)
DNA polymerase subunit gamma-2, mitochondrial	DNA polymerase gamma accessory 55 kDa subunit; p55; Mitochondrial DNA polymerase accessory subunit; MtPolB; PolG-beta	Homo sapiens (human)
Transcription termination factor 1, mitochondrial	Mitochondrial transcription termination factor 1; mTERF; mTERF1	Homo sapiens (human)
MICOS complex subunit MIC25	Coiled-coil-helix cristae morphology protein 1; Coiled-coil-helix-coiled-coil-helix domain-containing protein 6	Homo sapiens (human)
MICOS complex subunit MIC19	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3	Homo sapiens (human)
Peroxisome proliferator-activated receptor gamma coactivator 1-beta	PGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PGC-1-related estrogen receptor alpha coactivator	Homo sapiens (human)
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1	PGC-1-related coactivator; PRC	Homo sapiens (human)
Nuclear respiratory factor 1	NRF-1; Alpha palindromic-binding protein; Alpha-pal	Homo sapiens (human)
5-aminolevulinate synthase, nonspecific, mitochondrial	ALAS-H; EC 2.3.1.37; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1	Homo sapiens (human)
Metaxin-1	Mitochondrial outer membrane import complex protein 1	Homo sapiens (human)
F-box-like/WD repeat-containing protein TBL1X	SMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked	Homo sapiens (human)
Metaxin-2	Mitochondrial outer membrane import complex protein 2	Homo sapiens (human)
ATP synthase subunit d, mitochondrial	ATPase subunit d; ATP synthase peripheral stalk subunit d	Homo sapiens (human)
ATP synthase subunit g, mitochondrial	ATPase subunit g; ATP synthase membrane subunit g	Homo sapiens (human)
ATP synthase subunit a	F-ATPase protein 6	Homo sapiens (human)
ATP synthase protein 8	A6L; F-ATPase subunit 8	Homo sapiens (human)
ATP synthase F(0) complex subunit C1, mitochondrial	ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 1; ATP synthase proteolipid P1; ATP synthase proton-transporting mitochondrial F(0) complex subunit C1; ATPase protein 9; ATPase subunit c	Homo sapiens (human)
Transmembrane protein 11, mitochondrial	Protein PM1; Protein PMI	Homo sapiens (human)
ATP synthase-coupling factor 6, mitochondrial	ATPase subunit F6; ATP synthase peripheral stalk subunit F6	Homo sapiens (human)
ATP synthase F(0) complex subunit B1, mitochondrial	ATP synthase peripheral stalk-membrane subunit b; ATP synthase proton-transporting mitochondrial F(0) complex subunit B1; ATP synthase subunit b; ATPase subunit b	Homo sapiens (human)
ATP synthase subunit delta, mitochondrial	ATP synthase F1 subunit delta; F-ATPase delta subunit	Homo sapiens (human)
ATP synthase subunit O, mitochondrial	ATP synthase peripheral stalk subunit OSCP; Oligomycin sensitivity conferral protein; OSCP	Homo sapiens (human)
ATP synthase F(0) complex subunit C3, mitochondrial	ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 3; ATP synthase proteolipid P3; ATP synthase proton-transporting mitochondrial F(0) complex subunit C3; ATPase protein 9; ATPase subunit c	Homo sapiens (human)
ATP synthase subunit f, mitochondrial	ATP synthase membrane subunit f	Homo sapiens (human)
ATP synthase subunit epsilon, mitochondrial	ATPase subunit epsilon; ATP synthase F1 subunit epsilon	Homo sapiens (human)
ATP synthase subunit e, mitochondrial	ATPase subunit e; ATP synthase membrane subunit e	Homo sapiens (human)
Single-stranded DNA-binding protein, mitochondrial	Mt-SSB; MtSSB; PWP1-interacting protein 17	Homo sapiens (human)
ATP synthase F(0) complex subunit C2, mitochondrial	ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 2; ATP synthase proteolipid P2; ATP synthase proton-transporting mitochondrial F(0) complex subunit C2; ATPase protein 9; ATPase subunit c	Homo sapiens (human)
GA-binding protein alpha chain	GABP subunit alpha; Nuclear respiratory factor 2 subunit alpha; Transcription factor E4TF1-60	Homo sapiens (human)
PGC-1 and ERR-induced regulator in muscle protein 1	PPARGC1 and ESRR-induced regulator in muscle 1; Peroxisome proliferator-activated receptor gamma coactivator 1 and estrogen-related receptor-induced regulator in muscle 1	Homo sapiens (human)
MICOS complex subunit MIC13	Protein P117	Homo sapiens (human)
MICOS complex subunit MIC27	Apolipoprotein O-like; Protein FAM121A	Homo sapiens (human)
Dimethyladenosine transferase 1, mitochondrial	EC 2.1.1.-; Mitochondrial 12S rRNA dimethylase 1; Mitochondrial transcription factor B1; h-mtTFB; h-mtTFB1; hTFB1M; mtTFB1; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1	Homo sapiens (human)
Twinkle protein, mitochondrial	EC 3.6.4.12; Progressive external ophthalmoplegia 1 protein; T7 gp4-like protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; Twinkle mtDNA helicase	Homo sapiens (human)
ATP synthase subunit s, mitochondrial	ATP synthase-coupling factor B; FB; Distal membrane arm assembly complex 2-like protein; Mitochondrial ATP synthase regulatory component factor B	Homo sapiens (human)
MICOS complex subunit MIC26	Apolipoprotein O; MICOS complex subunit MIC23; Protein FAM121B	Homo sapiens (human)
Dimethyladenosine transferase 2, mitochondrial	EC 2.1.1.-; Hepatitis C virus NS5A-transactivated protein 5; HCV NS5A-transactivated protein 5; Mitochondrial 12S rRNA dimethylase 2; Mitochondrial transcription factor B2; h-mtTFB; h-mtTFB2; hTFB2M; mtTFB2; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) di	Homo sapiens (human)
DnaJ homolog subfamily C member 11		Homo sapiens (human)
Sorting and assembly machinery component 50 homolog	Transformation-related gene 3 protein; TRG-3	Homo sapiens (human)

Compounds (8)

Compound	Description
Calcium	A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Zinc	A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
adenosine diphosphate	Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
niacinamide	An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
o-acetyl-adp-ribose	An acetyl ester of ADENOSINE DIPHOSPHATE RIBOSE formed during NAD-dependent deacetylation of proteins by SIRTUINS. The acetate group resides on the ribose ring where nicotinamide was cleaved from NAD during the reaction. Several isomers of O-acetyl-ADP-ribose have been isolated from the reaction.
adenosine monophosphate	Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nad	A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.