| Protein | Synonyms | Taxonomy |
|---|
| Squalene monooxygenase | EC 1.14.14.17; Squalene epoxidase; SE | Homo sapiens (human) |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMG-CoA reductase; EC 1.1.1.34 | Homo sapiens (human) |
| Farnesyl pyrophosphate synthase | FPP synthase; FPS; EC 2.5.1.10; (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; 2.5.1.1; Farnesyl diphosphate synthase; Geranyltranstransferase | Homo sapiens (human) |
| Squalene synthase | SQS; SS; EC 2.5.1.21; FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase 1 | Homo sapiens (human) |
| Lanosterol synthase | EC 5.4.99.7; 2,3-epoxysqualene--lanosterol cyclase; Oxidosqualene--lanosterol cyclase; OSC; hOSC | Homo sapiens (human) |
| Diphosphomevalonate decarboxylase | EC 4.1.1.33; Mevalonate (diphospho)decarboxylase; MDDase; Mevalonate pyrophosphate decarboxylase | Homo sapiens (human) |
| Hydroxymethylglutaryl-CoA synthase, cytoplasmic | HMG-CoA synthase; EC 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthase | Homo sapiens (human) |
| Acetyl-CoA acetyltransferase, mitochondrial | EC 2.3.1.9; Acetoacetyl-CoA thiolase; T2 | Homo sapiens (human) |
| Isopentenyl-diphosphate Delta-isomerase 1 | EC 5.3.3.2; Isopentenyl pyrophosphate isomerase 1; IPP isomerase 1; IPPI1 | Homo sapiens (human) |
| Mevalonate kinase | MK; EC 2.7.1.36 | Homo sapiens (human) |
| Phosphomevalonate kinase | PMKase; hPMK; EC 2.7.4.2 | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| Orthophosphate | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| flavin mononucleotide | A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Coenzyme A | |
| isopentenyl pyrophosphate | substrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells |
| flavin mononucleotide hydroquinone | structure in first source |
| farnesyl pyrophosphate | a sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation |
| geranyl pyrophosphate | RN given refers to (E)-isomer |
| 5-diphosphomevalonic acid | RN given refers to ion(1-) |
| lanosterol | A triterpene that derives from the chair-boat-chair-boat folding of 2,3-oxidosqualene. It is metabolized to CHOLESTEROL and CUCURBITACINS. |
| mevalonic acid | A dihydroxy monocarboxylic acid and precursor in the biosynthetic pathway known as the mevalonate pathway, which produces terpenes and steroids that are vital for diverse cellular functions. |
| phosphomevalonate | |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| creolin | from refined coal tar oils |
| pyrophosphate | |
| 3,3-dimethylallyl pyrophosphate | isomeric with isopentenyl pyrophosphate |