Page last updated: 2024-10-06

Methylphenidate Pathway, Pharmacodynamics

Proteins (15)

ProteinSynonymsTaxonomy
5-hydroxytryptamine receptor 1A5-HT-1A; 5-HT1A; G-21; Serotonin receptor 1AHomo sapiens (human)
Alpha-2A adrenergic receptorAlpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoreceptor; Alpha-2A adrenoceptor; Alpha-2AARHomo sapiens (human)
D(2) dopamine receptorDopamine D2 receptorHomo sapiens (human)
D(1A) dopamine receptorDopamine D1 receptorHomo sapiens (human)
D(4) dopamine receptorD(2C) dopamine receptor; Dopamine D4 receptorHomo sapiens (human)
D(1B) dopamine receptorD(5) dopamine receptor; D1beta dopamine receptor; Dopamine D5 receptorHomo sapiens (human)
D(3) dopamine receptorDopamine D3 receptorHomo sapiens (human)
Synaptic vesicular amine transporterMonoamine transporter; Solute carrier family 18 member 2; Vesicular amine transporter 2; VAT2Homo sapiens (human)
Amine oxidase [flavin-containing] BEC 1.4.3.4; Monoamine oxidase type B; MAO-BHomo sapiens (human)
5-hydroxytryptamine receptor 1B5-HT-1B; 5-HT1B; S12; Serotonin 1D beta receptor; 5-HT-1D-beta; Serotonin receptor 1BHomo sapiens (human)
Tyrosine 3-monooxygenaseEC 1.14.16.2; Tyrosine 3-hydroxylase; THHomo sapiens (human)
Catechol O-methyltransferaseEC 2.1.1.6Homo sapiens (human)
Dopamine beta-hydroxylaseEC 1.14.17.1; Dopamine beta-monooxygenaseHomo sapiens (human)
Tryptophan 5-hydroxylase 2EC 1.14.16.4; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2Homo sapiens (human)
TransporterHomo sapiens (human)

Compounds (1)

CompoundDescription
SerotoninA biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.