Page last updated: 2024-10-06

Methylglyoxal Degradation I

Proteins (3)

ProteinSynonymsTaxonomy
Quinone-dependent D-lactate dehydrogenaseEC 1.1.5.12; (R)-lactate:quinone 2-oxidoreductase; D-lactate dehydrogenase; D-LDH; Respiratory D-lactate dehydrogenaseEscherichia coli K-12
Lactoylglutathione lyaseEC 4.4.1.5; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyaseEscherichia coli K-12
Hydroxyacylglutathione hydrolase GloBEC 3.1.2.6; Glyoxalase II; Glx IIEscherichia coli K-12

Compounds (7)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
l-lactic acid
GlutathioneA tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
ubiquinolreduced forms of ubiquinone; see also record for ubiquinol 10
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
pyruvaldehydeAn organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.