Page last updated: 2024-10-06
Methionine Metabolism and Salvage
Proteins (15)
| Protein | Synonyms | Taxonomy |
|---|---|---|
| Homoserine O-acetyltransferase | EC 2.3.1.31; Homoserine O-trans-acetylase | Saccharomyces cerevisiae S288C |
| Aspartokinase | EC 2.7.2.4; Aspartate kinase | Saccharomyces cerevisiae S288C |
| Adenosylhomocysteinase | AdoHcyase; EC 3.3.1.1; S-adenosyl-L-homocysteine hydrolase | Saccharomyces cerevisiae S288C |
| S-methyl-5'-thioadenosine phosphorylase | EC 2.4.2.28; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; Multicopy enhancer of UAS2 | Saccharomyces cerevisiae S288C |
| Homoserine dehydrogenase | HDH; EC 1.1.1.3 | Saccharomyces cerevisiae S288C |
| Homocysteine/cysteine synthase | EC 2.5.1.47; EC 2.5.1.49; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase | Saccharomyces cerevisiae S288C |
| S-adenosylmethionine synthase 1 | AdoMet synthase 1; EC 2.5.1.6; Methionine adenosyltransferase 1; MAT 1 | Saccharomyces cerevisiae S288C |
| S-adenosylmethionine synthase 2 | AdoMet synthase 2; EC 2.5.1.6; Methionine adenosyltransferase 2; MAT 2 | Saccharomyces cerevisiae S288C |
| 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | EC 2.1.1.14; Cobalamin-independent methionine synthase; Delta-P8 protein; Methionine synthase, vitamin-B12 independent isozyme | Saccharomyces cerevisiae S288C |
| Aromatic amino acid aminotransferase 2 | EC 2.6.1.57; Aromatic amino acid aminotransferase II; Aromatic amino acid-requiring protein 9; Kynurenine aminotransferase I; KAT I; 2.6.1.7 | Saccharomyces cerevisiae S288C |
| Enolase-phosphatase E1 | EC 3.1.3.77; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Unknown transcript 4 protein | Saccharomyces cerevisiae S288C |
| Methylthioribose-1-phosphate isomerase | M1Pi; MTR-1-P isomerase; EC 5.3.1.23; S-methyl-5-thioribose-1-phosphate isomerase; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein | Saccharomyces cerevisiae S288C |
| 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase | EC 1.13.11.54; Acireductone dioxygenase (Fe(2+)-requiring); ARD; Fe-ARD | Saccharomyces cerevisiae S288C |
| Aspartate-semialdehyde dehydrogenase | ASA dehydrogenase; ASADH; EC 1.2.1.11; Aspartate-beta-semialdehyde dehydrogenase | Saccharomyces cerevisiae S288C |
| Methylthioribulose-1-phosphate dehydratase | MTRu-1-P dehydratase; EC 4.2.1.109 | Saccharomyces cerevisiae S288C |
Compounds (23)
| Compound | Description |
|---|---|
| hydronium ion | |
| Orthophosphate | |
| acetic acid | Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) |
| adenine | A purine base and a fundamental unit of ADENINE NUCLEOTIDES. |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| adenosine | A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. |
| methionine | A sulfur-containing essential L-amino acid that is important in many body functions. |
| phenylalanine | An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Coenzyme A | |
| homoserine | |
| aspartic semialdehyde | RN given refers to cpd without isomeric designation |
| 2-keto-4-methylthiobutyric acid | RN given refers to parent cpd; structure |
| 1-phospho-2,3-diketo-5-S-methylthiopentane | metabolite found in conversion of 5'-S-methylthioadenosine to methionine in Klebsiella pneumoniae; structure given in first source |
| alpha-ketobutyric acid | RN given refers to parent cpd; structure |
| 1-phospho-5-S-methylthioribulose | |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| creolin | from refined coal tar oils |
| pyrophosphate | |
| Slc7a2 protein, mouse | RefSeq NM_007514 |