Page last updated: 2024-10-06

Metabolism of vitamins and cofactors

Proteins (138)

ProteinSynonymsTaxonomy
Apolipoprotein B-100Apo B-100Homo sapiens (human)
Serine hydroxymethyltransferase, mitochondrialSHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylaseHomo sapiens (human)
Sepiapterin reductaseSPR; EC 1.1.1.153Homo sapiens (human)
BiotinidaseBiotinase; EC 3.5.1.12Homo sapiens (human)
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2EC 3.2.2.6; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2Homo sapiens (human)
Vitamin K epoxide reductase complex subunit 1-like protein 1VKORC1-like protein 1; EC 1.17.4.4Homo sapiens (human)
Pantothenate kinase 2, mitochondrialhPanK2; EC 2.7.1.33; Pantothenic acid kinase 2Homo sapiens (human)
Heat shock protein HSP 90-alphaEC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38Homo sapiens (human)
RAC-alpha serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alphaHomo sapiens (human)
Multidrug resistance-associated protein 1 EC 7.6.2.2; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; 7.6.2.3; Leukotriene C(4) transporter; LTC4 transporterHomo sapiens (human)
Prostaglandin G/H synthase 2EC 1.14.99.1; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2Homo sapiens (human)
Fatty acid synthaseEC 2.3.1.85; Type I fatty acid synthaseHomo sapiens (human)
Glutamine-dependent NAD(+) synthetaseEC 6.3.5.1; NAD(+) synthase [glutamine-hydrolyzing]; NAD(+) synthetaseHomo sapiens (human)
Cobalamin trafficking protein CblDCblD; Methylmalonic aciduria and homocystinuria type D protein, mitochondrialHomo sapiens (human)
6-pyruvoyl tetrahydrobiopterin synthasePTP synthase; PTPS; EC 4.2.3.12Homo sapiens (human)
NAD kinaseEC 2.7.1.23; Poly(P)/ATP NAD kinaseHomo sapiens (human)
Cytochrome b5Microsomal cytochrome b5 type A; MCB5Homo sapiens (human)
Serine hydroxymethyltransferase, cytosolicSHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylaseHomo sapiens (human)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3E-NPP 3; NPP3; Phosphodiesterase I beta; PD-Ibeta; Phosphodiesterase I/nucleotide pyrophosphatase 3Homo sapiens (human)
Dihydrofolate reductaseEC 1.5.1.3Homo sapiens (human)
TransthyretinATTR; Prealbumin; TBPAHomo sapiens (human)
Reduced folate transporterFOLT; Intestinal folate carrier 1; IFC-1; Placental folate transporter; Reduced folate carrier protein; RFC; hRFC; Reduced folate transporter 1; RFT-1; Solute carrier family 19 member 1; hSLC19A1Homo sapiens (human)
Nicotinamide phosphoribosyltransferaseNAmPRTase; Nampt; EC 2.4.2.12; Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; VisfatinHomo sapiens (human)
Low-density lipoprotein receptor-related protein 2LRP-2; Glycoprotein 330; gp330; MegalinHomo sapiens (human)
Acetyl-CoA carboxylase 1ACC1; EC 6.4.1.2; Acetyl-Coenzyme A carboxylase alpha; ACC-alphaHomo sapiens (human)
cGMP-dependent protein kinase 2cGK 2; cGK2; EC 2.7.11.12; cGMP-dependent protein kinase II; cGKIIHomo sapiens (human)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2E-NPP 2; EC 3.1.4.39; Autotaxin; Extracellular lysophospholipase D; LysoPLDHomo sapiens (human)
Glutathione S-transferase omega-2GSTO-2; EC 2.5.1.18; Glutathione S-transferase omega 2-2; GSTO 2-2; Glutathione-dependent dehydroascorbate reductase; 1.8.5.1; Monomethylarsonic acid reductase; MMA(V) reductase; 1.20.4.2Homo sapiens (human)
Bifunctional coenzyme A synthaseCoA synthase; NBP; POV-2Homo sapiens (human)
Propionyl-CoA carboxylase alpha chain, mitochondrialPCCase subunit alpha; EC 6.4.1.3; Propanoyl-CoA:carbon dioxide ligase subunit alphaHomo sapiens (human)
Propionyl-CoA carboxylase beta chain, mitochondrialPCCase subunit beta; EC 6.4.1.3; Propanoyl-CoA:carbon dioxide ligase subunit betaHomo sapiens (human)
Pyridoxal kinaseEC 2.7.1.35; Pyridoxine kinaseHomo sapiens (human)
Folate receptor betaFR-beta; Folate receptor 2; Folate receptor, fetal/placental; Placental folate-binding protein; FBPHomo sapiens (human)
Pancreatic triacylglycerol lipasePL; PTL; Pancreatic lipase; EC 3.1.1.3Homo sapiens (human)
Alpha-tocopherol transfer proteinAlpha-TTPHomo sapiens (human)
Glutathione S-transferase omega-1GSTO-1; EC 2.5.1.18; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; 1.8.5.1; Monomethylarsonic acid reductase; MMA(V) reductase; 1.20.4.2; S-(Phenacyl)glutathione reductase; SPG-RHomo sapiens (human)
Thiamin pyrophosphokinase 1hTPK1; EC 2.7.6.2; Placental protein 20; PP20; Thiamine pyrophosphokinase 1Homo sapiens (human)
Low-density lipoprotein receptorLDL receptorHomo sapiens (human)
Apolipoprotein A-IApo-AI; ApoA-I; Apolipoprotein A1Homo sapiens (human)
Nicotinamide N-methyltransferaseEC 2.1.1.1Homo sapiens (human)
Vitamin K epoxide reductase complex subunit 1 EC 1.17.4.4; Vitamin K1 2,3-epoxide reductase subunit 1Homo sapiens (human)
Apolipoprotein C-IIIApo-CIII; ApoC-III; Apolipoprotein C3Homo sapiens (human)
Nicotinate phosphoribosyltransferaseNAPRTase; EC 6.3.4.21; FHA-HIT-interacting protein; Nicotinate phosphoribosyltransferase domain-containing protein 1Homo sapiens (human)
5-demethoxyubiquinone hydroxylase, mitochondrialDMQ hydroxylase; EC 1.14.99.60; Timing protein clk-1 homolog; Ubiquinone biosynthesis monooxygenase COQ7Homo sapiens (human)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1NMN/NaMN adenylyltransferase 1; EC 2.7.7.1; EC 2.7.7.18; Nicotinamide-nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 1; NaMN adenylyltransferase 1Homo sapiens (human)
Acetyl-CoA carboxylase 2EC 6.4.1.2; ACC-betaHomo sapiens (human)
Isocitrate dehydrogenase [NADP] cytoplasmicIDH; EC 1.1.1.42; Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylaseHomo sapiens (human)
Retinol-binding protein 4Plasma retinol-binding protein; PRBP; RBPHomo sapiens (human)
Calmodulin-1Homo sapiens (human)
5'-nucleotidase5'-NT; EC 3.1.3.5; Ecto-5'-nucleotidaseHomo sapiens (human)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1E-NPP 1; Membrane component chromosome 6 surface marker 1; Phosphodiesterase I/nucleotide pyrophosphatase 1; Plasma-cell membrane glycoprotein PC-1Homo sapiens (human)
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1EC 3.2.2.6; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2.4.99.20; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10Homo sapiens (human)
Nitric oxide synthase, endothelialEC 1.14.13.39; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIIIHomo sapiens (human)
Aldehyde oxidaseEC 1.2.3.1; Aldehyde oxidase 1; Azaheterocycle hydroxylase; 1.17.3.-Homo sapiens (human)
Proton-coupled folate transporterG21; Heme carrier protein 1; PCFT/HCP1; Solute carrier family 46 member 1Homo sapiens (human)
Methionine synthaseMS; EC 2.1.1.13; 5-methyltetrahydrofolate--homocysteine methyltransferase; Cobalamin-dependent methionine synthase; Vitamin-B12 dependent methionine synthaseHomo sapiens (human)
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferaseEC 2.7.8.7; 4'-phosphopantetheinyl transferase; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD-PPT; LYS5 orthologHomo sapiens (human)
Pyridoxine-5'-phosphate oxidaseEC 1.4.3.5; Pyridoxamine-phosphate oxidaseHomo sapiens (human)
Lecithin retinol acyltransferaseEC 2.3.1.135; Phosphatidylcholine--retinol O-acyltransferaseHomo sapiens (human)
NADH-cytochrome b5 reductase 3 B5R; Cytochrome b5 reductase; EC 1.6.2.2; Diaphorase-1Homo sapiens (human)
C-1-tetrahydrofolate synthase, cytoplasmicC1-THF synthaseHomo sapiens (human)
Retinol-binding protein 2Cellular retinol-binding protein II; CRBP-IIHomo sapiens (human)
Cyanocobalamin reductase / alkylcobalamin dealkylaseAlkylcobalamin:glutathione S-alkyltransferase; 2.5.1.151; CblC; Cyanocobalamin reductase (cyanide-eliminating); 1.16.1.6; Methylmalonic aciduria and homocystinuria type C protein; MMACHCHomo sapiens (human)
GephyrinHomo sapiens (human)
All-trans-retinol 13,14-reductaseEC 1.3.99.23; All-trans-13,14-dihydroretinol saturase; RetSat; PPAR-alpha-regulated and starvation-induced gene proteinHomo sapiens (human)
Biotin--protein ligaseEC 6.3.4.-; Biotin apo-protein ligaseHomo sapiens (human)
Adenylyltransferase and sulfurtransferase MOCS3Molybdenum cofactor synthesis protein 3; Molybdopterin synthase sulfurylase; MPT synthase sulfurylaseHomo sapiens (human)
FAD synthaseEC 2.7.7.2; FAD pyrophosphorylase; FMN adenylyltransferase; Flavin adenine dinucleotide synthaseHomo sapiens (human)
Riboflavin kinaseEC 2.7.1.26; ATP:riboflavin 5'-phosphotransferase; FlavokinaseHomo sapiens (human)
Monofunctional C1-tetrahydrofolate synthase, mitochondrialEC 6.3.4.3; Formyltetrahydrofolate synthetaseHomo sapiens (human)
Cubilin460 kDa receptor; Intestinal intrinsic factor receptor; Intrinsic factor-cobalamin receptor; Intrinsic factor-vitamin B12 receptorHomo sapiens (human)
Apolipoprotein MApo-M; ApoM; Protein G3aHomo sapiens (human)
Cytosolic 10-formyltetrahydrofolate dehydrogenase10-FTHFDH; FDH; EC 1.5.1.6; Aldehyde dehydrogenase family 1 member L1Homo sapiens (human)
Graves disease carrier proteinGDC; Graves disease autoantigen; GDA; Mitochondrial solute carrier protein homolog; Solute carrier family 25 member 16Homo sapiens (human)
Retinol-binding protein 1Cellular retinol-binding protein; CRBP; Cellular retinol-binding protein I; CRBP-IHomo sapiens (human)
5-formyltetrahydrofolate cyclo-ligaseEC 6.3.3.2; 5,10-methenyl-tetrahydrofolate synthetase; MTHFS; Methenyl-THF synthetaseHomo sapiens (human)
Apolipoprotein A-IIApo-AII; ApoA-II; Apolipoprotein A2Homo sapiens (human)
Apolipoprotein C-IIApo-CII; ApoC-II; Apolipoprotein C2Homo sapiens (human)
Apolipoprotein A-IVApo-AIV; ApoA-IV; Apolipoprotein A4Homo sapiens (human)
Pyruvate carboxylase, mitochondrialEC 6.4.1.1; Pyruvic carboxylase; PCBHomo sapiens (human)
Methylmalonyl-CoA mutase, mitochondrialMCM; EC 5.4.99.2; Methylmalonyl-CoA isomeraseHomo sapiens (human)
GTP cyclohydrolase 1EC 3.5.4.16; GTP cyclohydrolase I; GTP-CH-IHomo sapiens (human)
Phospholipase B1, membrane-associatedPhospholipase B; hPLB; Lysophospholipase; 3.1.1.5; Phospholipase A2; 3.1.1.4; Phospholipase B/lipase; PLB/LIP; Triacylglycerol lipase; 3.1.1.3Homo sapiens (human)
Methionine synthase reductase MSR; EC 1.16.1.8; Aquacobalamin reductase; AqCbl reductase; 1.16.1.-Homo sapiens (human)
RenalaseEC 1.6.3.5; Monoamine oxidase-C; MAO-CHomo sapiens (human)
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrialMCCase subunit alpha; EC 6.4.1.4; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alphaHomo sapiens (human)
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrialMCCase subunit beta; EC 6.4.1.4; 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit betaHomo sapiens (human)
Molybdenum cofactor sulfuraseMCS; MOS; MoCo sulfurase; hMCS; EC 2.8.1.9; Molybdenum cofactor sulfurtransferaseHomo sapiens (human)
CD320 antigen8D6 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; Transcobalamin receptor; TCblRHomo sapiens (human)
Molybdopterin synthase catalytic subunitEC 2.8.1.12; MOCO1-B; Molybdenum cofactor synthesis protein 2 large subunit; Molybdenum cofactor synthesis protein 2B; MOCS2B; Molybdopterin-synthase large subunit; MPT synthase large subunitHomo sapiens (human)
NAD kinase 2, mitochondrialEC 2.7.1.23; Mitochondrial NAD kinase; NAD kinase domain-containing protein 1, mitochondrialHomo sapiens (human)
Methylenetetrahydrofolate reductaseEC 1.5.1.20Homo sapiens (human)
Molybdopterin synthase sulfur carrier subunitMOCO1-A; Molybdenum cofactor synthesis protein 2 small subunit; Molybdenum cofactor synthesis protein 2A; MOCS2A; Molybdopterin-synthase small subunit; Sulfur carrier protein MOCS2AHomo sapiens (human)
Nicotinamide riboside kinase 2NRK 2; NmR-K 2; EC 2.7.1.22; Integrin beta-1-binding protein 3; Muscle integrin-binding protein; MIBP; Nicotinic acid riboside kinase 2; 2.7.1.173; Ribosylnicotinamide kinase 2; RNK 2; Ribosylnicotinic acid kinase 2Homo sapiens (human)
Nicotinamide riboside kinase 1NRK 1; NmR-K 1; EC 2.7.1.22; Nicotinic acid riboside kinase 1; 2.7.1.173; Ribosylnicotinamide kinase 1; RNK 1; Ribosylnicotinic acid kinase 1Homo sapiens (human)
Beta,beta-carotene 15,15'-dioxygenaseEC 1.13.11.63; Beta-carotene dioxygenase 1; Beta-carotene oxygenase 1Homo sapiens (human)
Cobalamin binding intrinsic factorGastric intrinsic factor; Intrinsic factor; IF; INFHomo sapiens (human)
Corrinoid adenosyltransferaseEC 2.5.1.17; Cob(II)alamin adenosyltransferase; Cob(II)yrinic acid a,c-diamide adenosyltransferase; Cobinamide/cobalamin adenosyltransferase; Methylmalonic aciduria type B proteinHomo sapiens (human)
ATP-dependent (S)-NAD(P)H-hydrate dehydrataseEC 4.2.1.93; ATP-dependent NAD(P)HX dehydratase; Carbohydrate kinase domain-containing protein; NAD(P)HX dehydrataseHomo sapiens (human)
NAD(P)H-hydrate epimeraseEC 5.1.99.6; Apolipoprotein A-I-binding protein; AI-BP; NAD(P)HX epimerase; YjeF N-terminal domain-containing protein 1; YjeF_N1Homo sapiens (human)
Low density lipoprotein receptor adapter protein 1Autosomal recessive hypercholesterolemia proteinHomo sapiens (human)
Lysosomal cobalamin transporter ABCD4ATP-binding cassette sub-family D member 4; PMP70-related protein; P70R; Peroxisomal membrane protein 1-like; PXMP1-L; Peroxisomal membrane protein 69; PMP69Homo sapiens (human)
Ubiquinone biosynthesis protein COQ9, mitochondrialHomo sapiens (human)
Apolipoprotein EApo-EHomo sapiens (human)
ColipaseHomo sapiens (human)
Tartrate-resistant acid phosphatase type 5TR-AP; EC 3.1.3.2; Tartrate-resistant acid ATPase; TrATPase; Type 5 acid phosphataseHomo sapiens (human)
Transcobalamin-1TC-1; Haptocorrin; HC; Protein R; Transcobalamin I; TC I; TCIHomo sapiens (human)
Transcobalamin-2TC-2; Transcobalamin II; TC II; TCIIHomo sapiens (human)
GTP cyclohydrolase 1 feedback regulatory proteinGFRP; GTP cyclohydrolase I feedback regulatory protein; p35Homo sapiens (human)
Nicotinate-nucleotide pyrophosphorylase [carboxylating]EC 2.4.2.19; Quinolinate phosphoribosyltransferase [decarboxylating]; QAPRTase; QPRTaseHomo sapiens (human)
Mitochondrial 10-formyltetrahydrofolate dehydrogenaseMitochondrial 10-FTHFDH; mtFDH; EC 1.5.1.6; Aldehyde dehydrogenase family 1 member L2Homo sapiens (human)
PDZ domain-containing protein 11ATPase-interacting PDZ protein; Plasma membrane calcium ATPase-interacting single-PDZ protein; PMCA-interacting single-PDZ proteinHomo sapiens (human)
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrialEC 2.1.1.201; Ubiquinone biosynthesis methyltransferase COQ5Homo sapiens (human)
All trans-polyprenyl-diphosphate synthase PDSS1All-trans-decaprenyl-diphosphate synthase subunit 1; 2.5.1.91; Decaprenyl pyrophosphate synthase subunit 1; Decaprenyl-diphosphate synthase subunit 1; Solanesyl-diphosphate synthase subunit 1; Trans-prenyltransferase 1; TPT 1Homo sapiens (human)
Dihydrofolate reductase 2, mitochondrialDihydrofolate reductase, mitochondrial; 1.5.1.3; Dihydrofolate reductase-like protein 1Homo sapiens (human)
All trans-polyprenyl-diphosphate synthase PDSS2All-trans-decaprenyl-diphosphate synthase subunit 2; 2.5.1.91; Candidate tumor suppressor protein; Decaprenyl pyrophosphate synthase subunit 2; Decaprenyl-diphosphate synthase subunit 2; Solanesyl-diphosphate synthase subunit 2Homo sapiens (human)
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1GPI-HBP1; GPI-anchored HDL-binding protein 1; High density lipoprotein-binding protein 1Homo sapiens (human)
Methylmalonic aciduria type A protein, mitochondrialEC 3.6.-.-Homo sapiens (human)
Sodium-coupled monocarboxylate transporter 1Apical iodide transporter; Electrogenic sodium monocarboxylate cotransporter; Sodium iodide-related cotransporter; Solute carrier family 5 member 8Homo sapiens (human)
Retinol dehydrogenase 11EC 1.1.1.300; Androgen-regulated short-chain dehydrogenase/reductase 1; HCV core-binding protein HCBP12; Prostate short-chain dehydrogenase/reductase 1; Retinal reductase 1; RalR1; Short chain dehydrogenase/reductase family 7C member 1Homo sapiens (human)
Dephospho-CoA kinase domain-containing proteinHomo sapiens (human)
Phosphopantothenoylcysteine decarboxylasePPC-DC; EC 4.1.1.36; CoaCHomo sapiens (human)
4-hydroxybenzoate polyprenyltransferase, mitochondrial 4-HB polyprenyltransferase; EC 2.5.1.39; 4-hydroxybenzoate decaprenyltransferase; COQ2 homolog; hCOQ2; Para-hydroxybenzoate--polyprenyltransferase; PHB:PPT; PHB:polyprenyltransferaseHomo sapiens (human)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3NMN/NaMN adenylyltransferase 3; Nicotinamide-nucleotide adenylyltransferase 3; NMN adenylyltransferase 3; Nicotinate-nucleotide adenylyltransferase 3; NaMN adenylyltransferase 3; 2.7.7.18; Pyridine nucleotide adenylyltransferase 3; PNAT-3; 2.7.7.1Homo sapiens (human)
NAD-capped RNA hydrolase NUDT12DeNADding enzyme NUDT12; EC 3.6.1.-; NADH pyrophosphatase NUDT12; 3.6.1.22; Nucleoside diphosphate-linked moiety X motif 12; Nudix motif 12Homo sapiens (human)
Thiamine-triphosphataseThTPase; EC 3.6.1.28Homo sapiens (human)
Protein amnionlessHomo sapiens (human)
Beta,beta-carotene 9',10'-oxygenaseEC 1.13.11.71; B-diox-II; Beta-carotene dioxygenase 2Homo sapiens (human)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2NMN/NaMN adenylyltransferase 2; EC 2.7.7.1; EC 2.7.7.18; Nicotinamide mononucleotide adenylyltransferase 2; NMN adenylyltransferase 2; Nicotinate-nucleotide adenylyltransferase 2; NaMN adenylyltransferase 2Homo sapiens (human)
Mitochondrial folate transporter/carrierSolute carrier family 25 member 32Homo sapiens (human)
Phosphopantothenate--cysteine ligaseEC 6.3.2.51; Phosphopantothenoylcysteine synthetase; PPC synthetaseHomo sapiens (human)
Mitochondrial thiamine pyrophosphate carrierMitochondrial uncoupling protein 1; Solute carrier family 25 member 19Homo sapiens (human)
Lysosomal cobalamin transport escort protein LMBD1LMBD1; HDAg-L-interacting protein NESI; LMBR1 domain-containing protein 1; Nuclear export signal-interacting proteinHomo sapiens (human)
Ubiquinone biosynthesis O-methyltransferase, mitochondrial3-demethylubiquinol 3-O-methyltransferase; 2.1.1.64; Polyprenyldihydroxybenzoate methyltransferase; 2.1.1.114Homo sapiens (human)
Solute carrier family 22 member 13Organic cation transporter-like 3; ORCTL-3Homo sapiens (human)
Sodium-dependent multivitamin transporterNa(+)-dependent multivitamin transporter; Solute carrier family 5 member 6Homo sapiens (human)
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrialEC 1.14.13.-; Coenzyme Q10 monooxygenase 6Homo sapiens (human)
UbiA prenyltransferase domain-containing protein 1EC 2.5.1.-; Transitional epithelial response protein 1Homo sapiens (human)

Compounds (102)

CompoundDescription
hydronium ion
pyridoxalThe 4-carboxyaldehyde form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
pyridoxineThe 4-methanol form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).
pyridoxine 5-phosphateRN given refers to parent cpd
thiamine3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.
folic acidA member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
d-alpha tocopherol
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
biotinA water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
NADH
Ammonium
molybdate ion
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
Glutathione DisulfideA GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
vitamin k 3A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Flavin MononucleotideA coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
retinol
Thiamine Triphosphate3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P',P''-trioxide. The triphosphate ester of thiamine. In Leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.
beta caroteneA carotenoid that is a precursor of VITAMIN A. Beta carotene is administered to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria (PORPHYRIA, ERYTHROPOIETIC).
retinol palmitateRN given refers to parent cpd; structure
epoprostenolA prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
Cobalamins
CholesterolThe principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
retinaldehydeA diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
niacinamideAn important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Nico-400
niacinA water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
palmitic acidA common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
ubiquinolreduced forms of ubiquinone; see also record for ubiquinol 10
10-formyltetrahydrofolate
5-methyltetrahydrofolate
molybdenum cofactoralso see records for molybdopterin cytosine dinucleotide and molybdopterin guanine dinucleotide
molybdenum cofactoralso see records for molybdopterin cytosine dinucleotide and molybdopterin guanine dinucleotide
dihydrofolateRN given refers to (L)-isomer
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
5,6,7,8-tetrahydrofolic acidRN given refers to (DL)-isomer
dyspropterinintermediate in biosynthetic pathway of tetrahydrobiopterin; structure given in first source
5,10-methylenetetrahydrofolate
cyclic pyranopterin monophosphate
sapropterinRN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
1,5-dihydro-FADchromophore component of E coli DNA photolyase
cobamamide
sapropterinRN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
menatetrenone epoxidemetabolite of menatetrenone
pyridoxamineThe 4-aminomethyl form of VITAMIN B 6. During transamination of amino acids, PYRIDOXAL PHOSPHATE is transiently converted into pyridoxamine phosphate.
pyridoxamine phosphateRN given refers to parent cpd; structure
isopentenyl pyrophosphatesubstrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
4-hydroxybenzoic acid
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
nicotinate ribonucleoside
alpha-Ketoglutarate
formate
5'-deoxyadenosinemain heading DEOXYADENOSINE refers to the 3' cpd
pantetheineAn intermediate in the pathway of coenzyme A formation in mammalian liver and some microorganisms.
nicotinamide-beta-riboside
prostaglandin h2A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins.
farnesyl pyrophosphatea sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation
13,14-dihydroretinol
n(1)-methylnicotinamideRN given refers to parent cpd
prostaglandin g2
menatetrenone
L-glycero-tetrulose
glutamate
Quinolinate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
geranylgeranyl pyrophosphateRN given refers to (E,E,E)-isomer
CysteineA thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
beta-apo-10'-carotenalstructure in first source
3-decaprenyl-4-hydroxybenzoateintermediate in biosynthesis of ubiquinone
pyridoxic acidThe catabolic product of most of VITAMIN B 6; (PYRIDOXINE; PYRIDOXAL; and PYRIDOXAMINE) which is excreted in the urine.
polyglutamineRN given for (D)-isomer
hydrogen cyanideHydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
Peroxynitrite
nicotinic acid adenine dinucleotideintermediate in the biosynthesis of NAD
4'-phosphopantothenate
adenosine 3'-phosphate-5'-phosphate
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
Nicotinamide Mononucleotide3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN.
s-adenosylhomocysteine5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.
Dehydroascorbic AcidThe reversibly oxidized form of ascorbic acid. It is the lactone of 2,3-DIKETOGULONIC ACID and has antiscorbutic activity in man on oral ingestion.
dephosphocoenzyme A
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
hemeThe color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.
creolinfrom refined coal tar oils
beta-iononestimulator of carotenogenesis; carotenoid inhibitor; intermediate in synthesis of Vit A; RN given refers to cpd without isomeric designation; structure
biocytin