Metabolism of vitamins and cofactors

Proteins (138)

Protein	Synonyms	Taxonomy
Apolipoprotein B-100	Apo B-100	Homo sapiens (human)
Serine hydroxymethyltransferase, mitochondrial	SHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylase	Homo sapiens (human)
Sepiapterin reductase	SPR; EC 1.1.1.153	Homo sapiens (human)
Biotinidase	Biotinase; EC 3.5.1.12	Homo sapiens (human)
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2	EC 3.2.2.6; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2	Homo sapiens (human)
Vitamin K epoxide reductase complex subunit 1-like protein 1	VKORC1-like protein 1; EC 1.17.4.4	Homo sapiens (human)
Pantothenate kinase 2, mitochondrial	hPanK2; EC 2.7.1.33; Pantothenic acid kinase 2	Homo sapiens (human)
Heat shock protein HSP 90-alpha	EC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38	Homo sapiens (human)
RAC-alpha serine/threonine-protein kinase	EC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha	Homo sapiens (human)
Multidrug resistance-associated protein 1	EC 7.6.2.2; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; 7.6.2.3; Leukotriene C(4) transporter; LTC4 transporter	Homo sapiens (human)
Prostaglandin G/H synthase 2	EC 1.14.99.1; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2	Homo sapiens (human)
Fatty acid synthase	EC 2.3.1.85; Type I fatty acid synthase	Homo sapiens (human)
Glutamine-dependent NAD(+) synthetase	EC 6.3.5.1; NAD(+) synthase [glutamine-hydrolyzing]; NAD(+) synthetase	Homo sapiens (human)
Cobalamin trafficking protein CblD	CblD; Methylmalonic aciduria and homocystinuria type D protein, mitochondrial	Homo sapiens (human)
6-pyruvoyl tetrahydrobiopterin synthase	PTP synthase; PTPS; EC 4.2.3.12	Homo sapiens (human)
NAD kinase	EC 2.7.1.23; Poly(P)/ATP NAD kinase	Homo sapiens (human)
Cytochrome b5	Microsomal cytochrome b5 type A; MCB5	Homo sapiens (human)
Serine hydroxymethyltransferase, cytosolic	SHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylase	Homo sapiens (human)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3	E-NPP 3; NPP3; Phosphodiesterase I beta; PD-Ibeta; Phosphodiesterase I/nucleotide pyrophosphatase 3	Homo sapiens (human)
Dihydrofolate reductase	EC 1.5.1.3	Homo sapiens (human)
Transthyretin	ATTR; Prealbumin; TBPA	Homo sapiens (human)
Reduced folate transporter	FOLT; Intestinal folate carrier 1; IFC-1; Placental folate transporter; Reduced folate carrier protein; RFC; hRFC; Reduced folate transporter 1; RFT-1; Solute carrier family 19 member 1; hSLC19A1	Homo sapiens (human)
Nicotinamide phosphoribosyltransferase	NAmPRTase; Nampt; EC 2.4.2.12; Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; Visfatin	Homo sapiens (human)
Low-density lipoprotein receptor-related protein 2	LRP-2; Glycoprotein 330; gp330; Megalin	Homo sapiens (human)
Acetyl-CoA carboxylase 1	ACC1; EC 6.4.1.2; Acetyl-Coenzyme A carboxylase alpha; ACC-alpha	Homo sapiens (human)
cGMP-dependent protein kinase 2	cGK 2; cGK2; EC 2.7.11.12; cGMP-dependent protein kinase II; cGKII	Homo sapiens (human)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	E-NPP 2; EC 3.1.4.39; Autotaxin; Extracellular lysophospholipase D; LysoPLD	Homo sapiens (human)
Glutathione S-transferase omega-2	GSTO-2; EC 2.5.1.18; Glutathione S-transferase omega 2-2; GSTO 2-2; Glutathione-dependent dehydroascorbate reductase; 1.8.5.1; Monomethylarsonic acid reductase; MMA(V) reductase; 1.20.4.2	Homo sapiens (human)
Bifunctional coenzyme A synthase	CoA synthase; NBP; POV-2	Homo sapiens (human)
Propionyl-CoA carboxylase alpha chain, mitochondrial	PCCase subunit alpha; EC 6.4.1.3; Propanoyl-CoA:carbon dioxide ligase subunit alpha	Homo sapiens (human)
Propionyl-CoA carboxylase beta chain, mitochondrial	PCCase subunit beta; EC 6.4.1.3; Propanoyl-CoA:carbon dioxide ligase subunit beta	Homo sapiens (human)
Pyridoxal kinase	EC 2.7.1.35; Pyridoxine kinase	Homo sapiens (human)
Folate receptor beta	FR-beta; Folate receptor 2; Folate receptor, fetal/placental; Placental folate-binding protein; FBP	Homo sapiens (human)
Pancreatic triacylglycerol lipase	PL; PTL; Pancreatic lipase; EC 3.1.1.3	Homo sapiens (human)
Alpha-tocopherol transfer protein	Alpha-TTP	Homo sapiens (human)
Glutathione S-transferase omega-1	GSTO-1; EC 2.5.1.18; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; 1.8.5.1; Monomethylarsonic acid reductase; MMA(V) reductase; 1.20.4.2; S-(Phenacyl)glutathione reductase; SPG-R	Homo sapiens (human)
Thiamin pyrophosphokinase 1	hTPK1; EC 2.7.6.2; Placental protein 20; PP20; Thiamine pyrophosphokinase 1	Homo sapiens (human)
Low-density lipoprotein receptor	LDL receptor	Homo sapiens (human)
Apolipoprotein A-I	Apo-AI; ApoA-I; Apolipoprotein A1	Homo sapiens (human)
Nicotinamide N-methyltransferase	EC 2.1.1.1	Homo sapiens (human)
Vitamin K epoxide reductase complex subunit 1	EC 1.17.4.4; Vitamin K1 2,3-epoxide reductase subunit 1	Homo sapiens (human)
Apolipoprotein C-III	Apo-CIII; ApoC-III; Apolipoprotein C3	Homo sapiens (human)
Nicotinate phosphoribosyltransferase	NAPRTase; EC 6.3.4.21; FHA-HIT-interacting protein; Nicotinate phosphoribosyltransferase domain-containing protein 1	Homo sapiens (human)
5-demethoxyubiquinone hydroxylase, mitochondrial	DMQ hydroxylase; EC 1.14.99.60; Timing protein clk-1 homolog; Ubiquinone biosynthesis monooxygenase COQ7	Homo sapiens (human)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1	NMN/NaMN adenylyltransferase 1; EC 2.7.7.1; EC 2.7.7.18; Nicotinamide-nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 1; NaMN adenylyltransferase 1	Homo sapiens (human)
Acetyl-CoA carboxylase 2	EC 6.4.1.2; ACC-beta	Homo sapiens (human)
Isocitrate dehydrogenase [NADP] cytoplasmic	IDH; EC 1.1.1.42; Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase	Homo sapiens (human)
Retinol-binding protein 4	Plasma retinol-binding protein; PRBP; RBP	Homo sapiens (human)
Calmodulin-1		Homo sapiens (human)
5'-nucleotidase	5'-NT; EC 3.1.3.5; Ecto-5'-nucleotidase	Homo sapiens (human)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	E-NPP 1; Membrane component chromosome 6 surface marker 1; Phosphodiesterase I/nucleotide pyrophosphatase 1; Plasma-cell membrane glycoprotein PC-1	Homo sapiens (human)
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	EC 3.2.2.6; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2.4.99.20; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10	Homo sapiens (human)
Nitric oxide synthase, endothelial	EC 1.14.13.39; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII	Homo sapiens (human)
Aldehyde oxidase	EC 1.2.3.1; Aldehyde oxidase 1; Azaheterocycle hydroxylase; 1.17.3.-	Homo sapiens (human)
Proton-coupled folate transporter	G21; Heme carrier protein 1; PCFT/HCP1; Solute carrier family 46 member 1	Homo sapiens (human)
Methionine synthase	MS; EC 2.1.1.13; 5-methyltetrahydrofolate--homocysteine methyltransferase; Cobalamin-dependent methionine synthase; Vitamin-B12 dependent methionine synthase	Homo sapiens (human)
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	EC 2.7.8.7; 4'-phosphopantetheinyl transferase; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD-PPT; LYS5 ortholog	Homo sapiens (human)
Pyridoxine-5'-phosphate oxidase	EC 1.4.3.5; Pyridoxamine-phosphate oxidase	Homo sapiens (human)
Lecithin retinol acyltransferase	EC 2.3.1.135; Phosphatidylcholine--retinol O-acyltransferase	Homo sapiens (human)
NADH-cytochrome b5 reductase 3	B5R; Cytochrome b5 reductase; EC 1.6.2.2; Diaphorase-1	Homo sapiens (human)
C-1-tetrahydrofolate synthase, cytoplasmic	C1-THF synthase	Homo sapiens (human)
Retinol-binding protein 2	Cellular retinol-binding protein II; CRBP-II	Homo sapiens (human)
Cyanocobalamin reductase / alkylcobalamin dealkylase	Alkylcobalamin:glutathione S-alkyltransferase; 2.5.1.151; CblC; Cyanocobalamin reductase (cyanide-eliminating); 1.16.1.6; Methylmalonic aciduria and homocystinuria type C protein; MMACHC	Homo sapiens (human)
Gephyrin		Homo sapiens (human)
All-trans-retinol 13,14-reductase	EC 1.3.99.23; All-trans-13,14-dihydroretinol saturase; RetSat; PPAR-alpha-regulated and starvation-induced gene protein	Homo sapiens (human)
Biotin--protein ligase	EC 6.3.4.-; Biotin apo-protein ligase	Homo sapiens (human)
Adenylyltransferase and sulfurtransferase MOCS3	Molybdenum cofactor synthesis protein 3; Molybdopterin synthase sulfurylase; MPT synthase sulfurylase	Homo sapiens (human)
FAD synthase	EC 2.7.7.2; FAD pyrophosphorylase; FMN adenylyltransferase; Flavin adenine dinucleotide synthase	Homo sapiens (human)
Riboflavin kinase	EC 2.7.1.26; ATP:riboflavin 5'-phosphotransferase; Flavokinase	Homo sapiens (human)
Monofunctional C1-tetrahydrofolate synthase, mitochondrial	EC 6.3.4.3; Formyltetrahydrofolate synthetase	Homo sapiens (human)
Cubilin	460 kDa receptor; Intestinal intrinsic factor receptor; Intrinsic factor-cobalamin receptor; Intrinsic factor-vitamin B12 receptor	Homo sapiens (human)
Apolipoprotein M	Apo-M; ApoM; Protein G3a	Homo sapiens (human)
Cytosolic 10-formyltetrahydrofolate dehydrogenase	10-FTHFDH; FDH; EC 1.5.1.6; Aldehyde dehydrogenase family 1 member L1	Homo sapiens (human)
Graves disease carrier protein	GDC; Graves disease autoantigen; GDA; Mitochondrial solute carrier protein homolog; Solute carrier family 25 member 16	Homo sapiens (human)
Retinol-binding protein 1	Cellular retinol-binding protein; CRBP; Cellular retinol-binding protein I; CRBP-I	Homo sapiens (human)
5-formyltetrahydrofolate cyclo-ligase	EC 6.3.3.2; 5,10-methenyl-tetrahydrofolate synthetase; MTHFS; Methenyl-THF synthetase	Homo sapiens (human)
Apolipoprotein A-II	Apo-AII; ApoA-II; Apolipoprotein A2	Homo sapiens (human)
Apolipoprotein C-II	Apo-CII; ApoC-II; Apolipoprotein C2	Homo sapiens (human)
Apolipoprotein A-IV	Apo-AIV; ApoA-IV; Apolipoprotein A4	Homo sapiens (human)
Pyruvate carboxylase, mitochondrial	EC 6.4.1.1; Pyruvic carboxylase; PCB	Homo sapiens (human)
Methylmalonyl-CoA mutase, mitochondrial	MCM; EC 5.4.99.2; Methylmalonyl-CoA isomerase	Homo sapiens (human)
GTP cyclohydrolase 1	EC 3.5.4.16; GTP cyclohydrolase I; GTP-CH-I	Homo sapiens (human)
Phospholipase B1, membrane-associated	Phospholipase B; hPLB; Lysophospholipase; 3.1.1.5; Phospholipase A2; 3.1.1.4; Phospholipase B/lipase; PLB/LIP; Triacylglycerol lipase; 3.1.1.3	Homo sapiens (human)
Methionine synthase reductase	MSR; EC 1.16.1.8; Aquacobalamin reductase; AqCbl reductase; 1.16.1.-	Homo sapiens (human)
Renalase	EC 1.6.3.5; Monoamine oxidase-C; MAO-C	Homo sapiens (human)
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	MCCase subunit alpha; EC 6.4.1.4; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha	Homo sapiens (human)
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	MCCase subunit beta; EC 6.4.1.4; 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta	Homo sapiens (human)
Molybdenum cofactor sulfurase	MCS; MOS; MoCo sulfurase; hMCS; EC 2.8.1.9; Molybdenum cofactor sulfurtransferase	Homo sapiens (human)
CD320 antigen	8D6 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; Transcobalamin receptor; TCblR	Homo sapiens (human)
Molybdopterin synthase catalytic subunit	EC 2.8.1.12; MOCO1-B; Molybdenum cofactor synthesis protein 2 large subunit; Molybdenum cofactor synthesis protein 2B; MOCS2B; Molybdopterin-synthase large subunit; MPT synthase large subunit	Homo sapiens (human)
NAD kinase 2, mitochondrial	EC 2.7.1.23; Mitochondrial NAD kinase; NAD kinase domain-containing protein 1, mitochondrial	Homo sapiens (human)
Methylenetetrahydrofolate reductase	EC 1.5.1.20	Homo sapiens (human)
Molybdopterin synthase sulfur carrier subunit	MOCO1-A; Molybdenum cofactor synthesis protein 2 small subunit; Molybdenum cofactor synthesis protein 2A; MOCS2A; Molybdopterin-synthase small subunit; Sulfur carrier protein MOCS2A	Homo sapiens (human)
Nicotinamide riboside kinase 2	NRK 2; NmR-K 2; EC 2.7.1.22; Integrin beta-1-binding protein 3; Muscle integrin-binding protein; MIBP; Nicotinic acid riboside kinase 2; 2.7.1.173; Ribosylnicotinamide kinase 2; RNK 2; Ribosylnicotinic acid kinase 2	Homo sapiens (human)
Nicotinamide riboside kinase 1	NRK 1; NmR-K 1; EC 2.7.1.22; Nicotinic acid riboside kinase 1; 2.7.1.173; Ribosylnicotinamide kinase 1; RNK 1; Ribosylnicotinic acid kinase 1	Homo sapiens (human)
Beta,beta-carotene 15,15'-dioxygenase	EC 1.13.11.63; Beta-carotene dioxygenase 1; Beta-carotene oxygenase 1	Homo sapiens (human)
Cobalamin binding intrinsic factor	Gastric intrinsic factor; Intrinsic factor; IF; INF	Homo sapiens (human)
Corrinoid adenosyltransferase	EC 2.5.1.17; Cob(II)alamin adenosyltransferase; Cob(II)yrinic acid a,c-diamide adenosyltransferase; Cobinamide/cobalamin adenosyltransferase; Methylmalonic aciduria type B protein	Homo sapiens (human)
ATP-dependent (S)-NAD(P)H-hydrate dehydratase	EC 4.2.1.93; ATP-dependent NAD(P)HX dehydratase; Carbohydrate kinase domain-containing protein; NAD(P)HX dehydratase	Homo sapiens (human)
NAD(P)H-hydrate epimerase	EC 5.1.99.6; Apolipoprotein A-I-binding protein; AI-BP; NAD(P)HX epimerase; YjeF N-terminal domain-containing protein 1; YjeF_N1	Homo sapiens (human)
Low density lipoprotein receptor adapter protein 1	Autosomal recessive hypercholesterolemia protein	Homo sapiens (human)
Lysosomal cobalamin transporter ABCD4	ATP-binding cassette sub-family D member 4; PMP70-related protein; P70R; Peroxisomal membrane protein 1-like; PXMP1-L; Peroxisomal membrane protein 69; PMP69	Homo sapiens (human)
Ubiquinone biosynthesis protein COQ9, mitochondrial		Homo sapiens (human)
Apolipoprotein E	Apo-E	Homo sapiens (human)
Colipase		Homo sapiens (human)
Tartrate-resistant acid phosphatase type 5	TR-AP; EC 3.1.3.2; Tartrate-resistant acid ATPase; TrATPase; Type 5 acid phosphatase	Homo sapiens (human)
Transcobalamin-1	TC-1; Haptocorrin; HC; Protein R; Transcobalamin I; TC I; TCI	Homo sapiens (human)
Transcobalamin-2	TC-2; Transcobalamin II; TC II; TCII	Homo sapiens (human)
GTP cyclohydrolase 1 feedback regulatory protein	GFRP; GTP cyclohydrolase I feedback regulatory protein; p35	Homo sapiens (human)
Nicotinate-nucleotide pyrophosphorylase [carboxylating]	EC 2.4.2.19; Quinolinate phosphoribosyltransferase [decarboxylating]; QAPRTase; QPRTase	Homo sapiens (human)
Mitochondrial 10-formyltetrahydrofolate dehydrogenase	Mitochondrial 10-FTHFDH; mtFDH; EC 1.5.1.6; Aldehyde dehydrogenase family 1 member L2	Homo sapiens (human)
PDZ domain-containing protein 11	ATPase-interacting PDZ protein; Plasma membrane calcium ATPase-interacting single-PDZ protein; PMCA-interacting single-PDZ protein	Homo sapiens (human)
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial	EC 2.1.1.201; Ubiquinone biosynthesis methyltransferase COQ5	Homo sapiens (human)
All trans-polyprenyl-diphosphate synthase PDSS1	All-trans-decaprenyl-diphosphate synthase subunit 1; 2.5.1.91; Decaprenyl pyrophosphate synthase subunit 1; Decaprenyl-diphosphate synthase subunit 1; Solanesyl-diphosphate synthase subunit 1; Trans-prenyltransferase 1; TPT 1	Homo sapiens (human)
Dihydrofolate reductase 2, mitochondrial	Dihydrofolate reductase, mitochondrial; 1.5.1.3; Dihydrofolate reductase-like protein 1	Homo sapiens (human)
All trans-polyprenyl-diphosphate synthase PDSS2	All-trans-decaprenyl-diphosphate synthase subunit 2; 2.5.1.91; Candidate tumor suppressor protein; Decaprenyl pyrophosphate synthase subunit 2; Decaprenyl-diphosphate synthase subunit 2; Solanesyl-diphosphate synthase subunit 2	Homo sapiens (human)
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1	GPI-HBP1; GPI-anchored HDL-binding protein 1; High density lipoprotein-binding protein 1	Homo sapiens (human)
Methylmalonic aciduria type A protein, mitochondrial	EC 3.6.-.-	Homo sapiens (human)
Sodium-coupled monocarboxylate transporter 1	Apical iodide transporter; Electrogenic sodium monocarboxylate cotransporter; Sodium iodide-related cotransporter; Solute carrier family 5 member 8	Homo sapiens (human)
Retinol dehydrogenase 11	EC 1.1.1.300; Androgen-regulated short-chain dehydrogenase/reductase 1; HCV core-binding protein HCBP12; Prostate short-chain dehydrogenase/reductase 1; Retinal reductase 1; RalR1; Short chain dehydrogenase/reductase family 7C member 1	Homo sapiens (human)
Dephospho-CoA kinase domain-containing protein		Homo sapiens (human)
Phosphopantothenoylcysteine decarboxylase	PPC-DC; EC 4.1.1.36; CoaC	Homo sapiens (human)
4-hydroxybenzoate polyprenyltransferase, mitochondrial	4-HB polyprenyltransferase; EC 2.5.1.39; 4-hydroxybenzoate decaprenyltransferase; COQ2 homolog; hCOQ2; Para-hydroxybenzoate--polyprenyltransferase; PHB:PPT; PHB:polyprenyltransferase	Homo sapiens (human)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3	NMN/NaMN adenylyltransferase 3; Nicotinamide-nucleotide adenylyltransferase 3; NMN adenylyltransferase 3; Nicotinate-nucleotide adenylyltransferase 3; NaMN adenylyltransferase 3; 2.7.7.18; Pyridine nucleotide adenylyltransferase 3; PNAT-3; 2.7.7.1	Homo sapiens (human)
NAD-capped RNA hydrolase NUDT12	DeNADding enzyme NUDT12; EC 3.6.1.-; NADH pyrophosphatase NUDT12; 3.6.1.22; Nucleoside diphosphate-linked moiety X motif 12; Nudix motif 12	Homo sapiens (human)
Thiamine-triphosphatase	ThTPase; EC 3.6.1.28	Homo sapiens (human)
Protein amnionless		Homo sapiens (human)
Beta,beta-carotene 9',10'-oxygenase	EC 1.13.11.71; B-diox-II; Beta-carotene dioxygenase 2	Homo sapiens (human)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2	NMN/NaMN adenylyltransferase 2; EC 2.7.7.1; EC 2.7.7.18; Nicotinamide mononucleotide adenylyltransferase 2; NMN adenylyltransferase 2; Nicotinate-nucleotide adenylyltransferase 2; NaMN adenylyltransferase 2	Homo sapiens (human)
Mitochondrial folate transporter/carrier	Solute carrier family 25 member 32	Homo sapiens (human)
Phosphopantothenate--cysteine ligase	EC 6.3.2.51; Phosphopantothenoylcysteine synthetase; PPC synthetase	Homo sapiens (human)
Mitochondrial thiamine pyrophosphate carrier	Mitochondrial uncoupling protein 1; Solute carrier family 25 member 19	Homo sapiens (human)
Lysosomal cobalamin transport escort protein LMBD1	LMBD1; HDAg-L-interacting protein NESI; LMBR1 domain-containing protein 1; Nuclear export signal-interacting protein	Homo sapiens (human)
Ubiquinone biosynthesis O-methyltransferase, mitochondrial	3-demethylubiquinol 3-O-methyltransferase; 2.1.1.64; Polyprenyldihydroxybenzoate methyltransferase; 2.1.1.114	Homo sapiens (human)
Solute carrier family 22 member 13	Organic cation transporter-like 3; ORCTL-3	Homo sapiens (human)
Sodium-dependent multivitamin transporter	Na(+)-dependent multivitamin transporter; Solute carrier family 5 member 6	Homo sapiens (human)
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial	EC 1.14.13.-; Coenzyme Q10 monooxygenase 6	Homo sapiens (human)
UbiA prenyltransferase domain-containing protein 1	EC 2.5.1.-; Transitional epithelial response protein 1	Homo sapiens (human)

Compounds (102)

Compound	Description
hydronium ion
pyridoxal	The 4-carboxyaldehyde form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
pyridoxine	The 4-methanol form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).
pyridoxine 5-phosphate	RN given refers to parent cpd
thiamine	3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.
folic acid	A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
d-alpha tocopherol
Thiamine Pyrophosphate	The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
biotin	A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
NADH
Ammonium
molybdate ion
Calcium	A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
iron	A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Manganese	A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon Dioxide	A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Iron	A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Zinc	A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
Glutathione Disulfide	A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
vitamin k 3	A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Flavin Mononucleotide	A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
retinol
Thiamine Triphosphate	3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P',P''-trioxide. The triphosphate ester of thiamine. In Leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.
beta carotene	A carotenoid that is a precursor of VITAMIN A. Beta carotene is administered to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria (PORPHYRIA, ERYTHROPOIETIC).
retinol palmitate	RN given refers to parent cpd; structure
epoprostenol	A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
Cobalamins
Cholesterol	The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
retinaldehyde	A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer.
adenosine diphosphate	Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Hydrogen Peroxide	A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
Magnesium	A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
Sodium	A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
niacinamide	An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Nico-400
niacin	A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
Water	A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
palmitic acid	A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
ubiquinol	reduced forms of ubiquinone; see also record for ubiquinol 10
10-formyltetrahydrofolate
5-methyltetrahydrofolate
molybdenum cofactor	also see records for molybdopterin cytosine dinucleotide and molybdopterin guanine dinucleotide
molybdenum cofactor	also see records for molybdopterin cytosine dinucleotide and molybdopterin guanine dinucleotide
dihydrofolate	RN given refers to (L)-isomer
Guanosine Monophosphate	A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
5,6,7,8-tetrahydrofolic acid	RN given refers to (DL)-isomer
dyspropterin	intermediate in biosynthetic pathway of tetrahydrobiopterin; structure given in first source
5,10-methylenetetrahydrofolate
cyclic pyranopterin monophosphate
sapropterin	RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
1,5-dihydro-FAD	chromophore component of E coli DNA photolyase
cobamamide
sapropterin	RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
menatetrenone epoxide	metabolite of menatetrenone
pyridoxamine	The 4-aminomethyl form of VITAMIN B 6. During transamination of amino acids, PYRIDOXAL PHOSPHATE is transiently converted into pyridoxamine phosphate.
pyridoxamine phosphate	RN given refers to parent cpd; structure
isopentenyl pyrophosphate	substrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
4-hydroxybenzoic acid
adenosine monophosphate	Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nad	A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADP	Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADP	Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
nicotinate ribonucleoside
alpha-Ketoglutarate
formate
5'-deoxyadenosine	main heading DEOXYADENOSINE refers to the 3' cpd
pantetheine	An intermediate in the pathway of coenzyme A formation in mammalian liver and some microorganisms.
nicotinamide-beta-riboside
prostaglandin h2	A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins.
farnesyl pyrophosphate	a sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation
13,14-dihydroretinol
n(1)-methylnicotinamide	RN given refers to parent cpd
prostaglandin g2
menatetrenone
L-glycero-tetrulose
glutamate
Quinolinate
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
geranylgeranyl pyrophosphate	RN given refers to (E,E,E)-isomer
Cysteine	A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
beta-apo-10'-carotenal	structure in first source
3-decaprenyl-4-hydroxybenzoate	intermediate in biosynthesis of ubiquinone
pyridoxic acid	The catabolic product of most of VITAMIN B 6; (PYRIDOXINE; PYRIDOXAL; and PYRIDOXAMINE) which is excreted in the urine.
polyglutamine	RN given for (D)-isomer
hydrogen cyanide	Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
Peroxynitrite
nicotinic acid adenine dinucleotide	intermediate in the biosynthesis of NAD
4'-phosphopantothenate
adenosine 3'-phosphate-5'-phosphate
s-adenosylmethionine	Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
Nicotinamide Mononucleotide	3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN.
s-adenosylhomocysteine	5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.
Dehydroascorbic Acid	The reversibly oxidized form of ascorbic acid. It is the lactone of 2,3-DIKETOGULONIC ACID and has antiscorbutic activity in man on oral ingestion.
dephosphocoenzyme A
Flavin-Adenine Dinucleotide	A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
heme	The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.
creolin	from refined coal tar oils
beta-ionone	stimulator of carotenogenesis; carotenoid inhibitor; intermediate in synthesis of Vit A; RN given refers to cpd without isomeric designation; structure
biocytin

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Metabolism of vitamins and cofactors

Proteins (138)

Compounds (102)