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Metabolism of ingested SeMet, Sec, MeSec into H2Se

Proteins (4)

ProteinSynonymsTaxonomy
Cystathionine gamma-lyaseEC 4.4.1.1; Cysteine-protein sulfhydrase; Gamma-cystathionaseHomo sapiens (human)
AdenosylhomocysteinaseAdoHcyase; EC 3.3.1.1; S-adenosyl-L-homocysteine hydrolaseHomo sapiens (human)
Cystathionine beta-synthaseEC 4.2.1.22; Beta-thionase; Serine sulfhydraseHomo sapiens (human)
Selenocysteine lyasehSCL; EC 4.4.1.16Homo sapiens (human)

Compounds (16)

CompoundDescription
selenomethionineDiagnostic aid in pancreas function determination.
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
Orthophosphate
adenosineA nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
selenocysteineA naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid.
methanolA colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
hydrogen selenideRN given refers to parent cpd
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
alpha-ketobutyric acidRN given refers to parent cpd; structure
methaneselenolRN given refers to (75)Se-labeled cpd
selenomethylselenocysteineRN given refers to parent cpd
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
selenocystathioninestructure in first source
hemeThe color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.