| Protein | Synonyms | Taxonomy |
|---|
| Serine hydroxymethyltransferase, mitochondrial | SHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylase | Homo sapiens (human) |
| Serine hydroxymethyltransferase, cytosolic | SHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylase | Homo sapiens (human) |
| Dihydrofolate reductase | EC 1.5.1.3 | Homo sapiens (human) |
| Reduced folate transporter | FOLT; Intestinal folate carrier 1; IFC-1; Placental folate transporter; Reduced folate carrier protein; RFC; hRFC; Reduced folate transporter 1; RFT-1; Solute carrier family 19 member 1; hSLC19A1 | Homo sapiens (human) |
| Folate receptor beta | FR-beta; Folate receptor 2; Folate receptor, fetal/placental; Placental folate-binding protein; FBP | Homo sapiens (human) |
| Proton-coupled folate transporter | G21; Heme carrier protein 1; PCFT/HCP1; Solute carrier family 46 member 1 | Homo sapiens (human) |
| C-1-tetrahydrofolate synthase, cytoplasmic | C1-THF synthase | Homo sapiens (human) |
| Monofunctional C1-tetrahydrofolate synthase, mitochondrial | EC 6.3.4.3; Formyltetrahydrofolate synthetase | Homo sapiens (human) |
| Cytosolic 10-formyltetrahydrofolate dehydrogenase | 10-FTHFDH; FDH; EC 1.5.1.6; Aldehyde dehydrogenase family 1 member L1 | Homo sapiens (human) |
| 5-formyltetrahydrofolate cyclo-ligase | EC 6.3.3.2; 5,10-methenyl-tetrahydrofolate synthetase; MTHFS; Methenyl-THF synthetase | Homo sapiens (human) |
| Methylenetetrahydrofolate reductase | EC 1.5.1.20 | Homo sapiens (human) |
| Mitochondrial 10-formyltetrahydrofolate dehydrogenase | Mitochondrial 10-FTHFDH; mtFDH; EC 1.5.1.6; Aldehyde dehydrogenase family 1 member L2 | Homo sapiens (human) |
| Dihydrofolate reductase 2, mitochondrial | Dihydrofolate reductase, mitochondrial; 1.5.1.3; Dihydrofolate reductase-like protein 1 | Homo sapiens (human) |
| Mitochondrial folate transporter/carrier | Solute carrier family 25 member 32 | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| folic acid | A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. |
| NADH | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| 10-formyltetrahydrofolate | |
| 5-methyltetrahydrofolate | |
| dihydrofolate | RN given refers to (L)-isomer |
| 5,6,7,8-tetrahydrofolic acid | RN given refers to (DL)-isomer |
| 5,10-methylenetetrahydrofolate | |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| formate | |
| glutamate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| creolin | from refined coal tar oils |