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Metabolic reprogramming in colon cancer
Proteins (0)
Compounds (27)
| Compound | Description |
|---|---|
| pyruvic acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| l-lactic acid | |
| Glutathione | A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides. |
| ammonium hydroxide | The hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution. |
| citric acid, anhydrous | |
| fumaric acid | see also record for ferrous fumarate; use FUMARATES for general fumaric acid esters |
| asparagine | A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed) |
| Glutamine | A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells. |
| glycine | A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. |
| inosinic acid | |
| phosphoenolpyruvate | A monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in GLYCOLYSIS; GLUCONEOGENESIS; and other pathways. |
| fructose-1,6-diphosphate | RN refers to (D)-isomer |
| erythrose 4-phosphate | RN given refers to (R-(R*,R*))-isomer |
| alpha-Ketoglutarate | |
| glyceraldehyde 3-phosphate | An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis. |
| glycerate 1,3-biphosphate | |
| Glutamate | |
| isocitrate | |
| 2-phosphoglycerate | RN given refers to cpd without isomeric designation |
| Glucose-6-Phosphate | An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed) |
| Proline | A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons. |
| Serine | A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. |
| 3-phosphoglycerate | |
| succinyl-coenzyme a | |
| oxaloacetic acid | A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE. |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| 6-phosphogluconic acid |