Page last updated: 2024-10-06

Metabolic pathways of fibroblasts

Proteins (16)

ProteinSynonymsTaxonomy
Bone morphogenetic protein 1BMP-1; EC 3.4.24.19; Mammalian tolloid protein; mTld; Procollagen C-proteinase; PCPHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
Solute carrier family 2, facilitated glucose transporter member 1Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporterHomo sapiens (human)
Hexokinase-4HK4; EC 2.7.1.1; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-DHomo sapiens (human)
Delta-1-pyrroline-5-carboxylate synthaseP5CS; Aldehyde dehydrogenase family 18 member A1Homo sapiens (human)
Pyrroline-5-carboxylate reductase 1, mitochondrialP5C reductase 1; P5CR 1; EC 1.5.1.2Homo sapiens (human)
Monocarboxylate transporter 1MCT 1; Solute carrier family 16 member 1Homo sapiens (human)
D-3-phosphoglycerate dehydrogenase3-PGDH; EC 1.1.1.95; 2-oxoglutarate reductase; 1.1.1.399; Malate dehydrogenase; 1.1.1.37Homo sapiens (human)
Glutaminase kidney isoform, mitochondrialGLS; EC 3.5.1.2; K-glutaminase; L-glutamine amidohydrolaseHomo sapiens (human)
Transforming protein RhoAEC 3.6.5.2; Rho cDNA clone 12; h12Homo sapiens (human)
Phosphoserine phosphatasePSP; PSPase; EC 3.1.3.3; L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolaseHomo sapiens (human)
Phosphoserine aminotransferaseEC 2.6.1.52; Phosphohydroxythreonine aminotransferase; PSATHomo sapiens (human)
UDP-glucose 6-dehydrogenaseUDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH; EC 1.1.1.22Homo sapiens (human)
Glutamate dehydrogenase 1, mitochondrialGDH 1; EC 1.4.1.3Homo sapiens (human)
Phosphoglucomutase-1PGM 1; EC 5.4.2.2; Glucose phosphomutase 1Homo sapiens (human)
UTP--glucose-1-phosphate uridylyltransferaseEC 2.7.7.9; UDP-glucose pyrophosphorylase; UDPGP; UGPaseHomo sapiens (human)

Compounds (17)

CompoundDescription
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
l-lactic acid
glutamineA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.
glucose, (beta-d)-isomer
glycineA non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
heparitin sulfateA heteropolysaccharide that is similar in structure to HEPARIN. It accumulates in individuals with MUCOPOLYSACCHARIDOSIS.
prolineA non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.
uridine diphosphate glucuronic acidA nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones.
Uridine Diphosphate GlucoseA key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
alpha-ketoglutaric acid
glutamate
Glucose-6-PhosphateAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
SerineA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
fructose-6-phosphateRN given refers to parent cpd with unspecified isomeric designation
3-phosphoglycerate
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
glucose-1-phosphateRN given refers to (alpha-D-Glc)-isomer