Page last updated: 2024-10-06
Metabolic pathways of fibroblasts
Proteins (16)
| Protein | Synonyms | Taxonomy |
|---|---|---|
| Bone morphogenetic protein 1 | BMP-1; EC 3.4.24.19; Mammalian tolloid protein; mTld; Procollagen C-proteinase; PCP | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1 | Homo sapiens (human) |
| Solute carrier family 2, facilitated glucose transporter member 1 | Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter | Homo sapiens (human) |
| Hexokinase-4 | HK4; EC 2.7.1.1; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-D | Homo sapiens (human) |
| Delta-1-pyrroline-5-carboxylate synthase | P5CS; Aldehyde dehydrogenase family 18 member A1 | Homo sapiens (human) |
| Pyrroline-5-carboxylate reductase 1, mitochondrial | P5C reductase 1; P5CR 1; EC 1.5.1.2 | Homo sapiens (human) |
| Monocarboxylate transporter 1 | MCT 1; Solute carrier family 16 member 1 | Homo sapiens (human) |
| D-3-phosphoglycerate dehydrogenase | 3-PGDH; EC 1.1.1.95; 2-oxoglutarate reductase; 1.1.1.399; Malate dehydrogenase; 1.1.1.37 | Homo sapiens (human) |
| Glutaminase kidney isoform, mitochondrial | GLS; EC 3.5.1.2; K-glutaminase; L-glutamine amidohydrolase | Homo sapiens (human) |
| Transforming protein RhoA | EC 3.6.5.2; Rho cDNA clone 12; h12 | Homo sapiens (human) |
| Phosphoserine phosphatase | PSP; PSPase; EC 3.1.3.3; L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase | Homo sapiens (human) |
| Phosphoserine aminotransferase | EC 2.6.1.52; Phosphohydroxythreonine aminotransferase; PSAT | Homo sapiens (human) |
| UDP-glucose 6-dehydrogenase | UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH; EC 1.1.1.22 | Homo sapiens (human) |
| Glutamate dehydrogenase 1, mitochondrial | GDH 1; EC 1.4.1.3 | Homo sapiens (human) |
| Phosphoglucomutase-1 | PGM 1; EC 5.4.2.2; Glucose phosphomutase 1 | Homo sapiens (human) |
| UTP--glucose-1-phosphate uridylyltransferase | EC 2.7.7.9; UDP-glucose pyrophosphorylase; UDPGP; UGPase | Homo sapiens (human) |
Compounds (17)
| Compound | Description |
|---|---|
| pyruvic acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| l-lactic acid | |
| glutamine | A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells. |
| glucose, (beta-d)-isomer | |
| glycine | A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. |
| heparitin sulfate | A heteropolysaccharide that is similar in structure to HEPARIN. It accumulates in individuals with MUCOPOLYSACCHARIDOSIS. |
| proline | A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons. |
| uridine diphosphate glucuronic acid | A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. |
| Uridine Diphosphate Glucose | A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids. |
| alpha-ketoglutaric acid | |
| glutamate | |
| Glucose-6-Phosphate | An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed) |
| Serine | A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. |
| fructose-6-phosphate | RN given refers to parent cpd with unspecified isomeric designation |
| 3-phosphoglycerate | |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| glucose-1-phosphate | RN given refers to (alpha-D-Glc)-isomer |