Page last updated: 2024-10-06

Melanin biosynthesis

Proteins (5)

ProteinSynonymsTaxonomy
5,6-dihydroxyindole-2-carboxylic acid oxidaseDHICA oxidase; EC 1.14.18.-; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1; TRP; TRP-1; TRP1Homo sapiens (human)
TyrosinaseEC 1.14.18.1; LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen ABHomo sapiens (human)
L-dopachrome tautomeraseDCT; DT; EC 5.3.3.12; L-dopachrome Delta-isomerase; Tyrosinase-related protein 2; TRP-2; TRP2Homo sapiens (human)
P proteinMelanocyte-specific transporter protein; Pink-eyed dilution protein homologHomo sapiens (human)
Membrane-associated transporter proteinMelanoma antigen AIM1; Protein AIM-1; Solute carrier family 45 member 2Homo sapiens (human)

Compounds (12)

CompoundDescription
hydronium ion
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
dopachromecyclization product of L-DOPA
leukodopachromeproposed metabolite in pathway from tyrosine to dopachrome; RN given refers to (S)-isomer; structure given in first source
dopaquinoneproposed metabolite in pathway from tyrosine to dopachrome; RN given refers to cpd without isomeric designation; structure given in first source
CysteineA thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
5,6-dihydroxyindole
hydroxyl radicalThe univalent radical OH. Hydroxyl radical is a potent oxidizing agent.