Page last updated: 2024-10-06

Maternal to zygotic transition (MZT)

Proteins (40)

ProteinSynonymsTaxonomy
Methylcytosine dioxygenase TET3EC 1.14.11.n2Homo sapiens (human)
Transcriptional enhancer factor TEF-3TEA domain family member 4; TEAD-4; Transcription factor 13-like 1; Transcription factor RTEF-1Homo sapiens (human)
Lysine-specific demethylase 5BEC 1.14.11.67; Cancer/testis antigen 31; CT31; Histone demethylase JARID1B; Jumonji/ARID domain-containing protein 1B; PLU-1; Retinoblastoma-binding protein 2 homolog 1; RBP2-H1; [histone H3]-trimethyl-L-lysine(4) demethylase 5BHomo sapiens (human)
Transcriptional coactivator YAP1Yes-associated protein 1; Protein yorkie homolog; Yes-associated protein YAP65 homologHomo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
Eukaryotic translation initiation factor 4EeIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding proteinHomo sapiens (human)
Eukaryotic translation initiation factor 4 gamma 1eIF-4-gamma 1; eIF-4G 1; eIF-4G1; p220Homo sapiens (human)
Uracil-DNA glycosylaseUDG; EC 3.2.2.27Homo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
SRSF protein kinase 1EC 2.7.11.1; SFRS protein kinase 1; Serine/arginine-rich protein-specific kinase 1; SR-protein-specific kinase 1Homo sapiens (human)
CCR4-NOT transcription complex subunit 1CCR4-associated factor 1; Negative regulator of transcription subunit 1 homolog; NOT1H; hNOT1Homo sapiens (human)
Single-stranded DNA cytosine deaminaseEC 3.5.4.38; Activation-induced cytidine deaminase; AID; Cytidine aminohydrolaseHomo sapiens (human)
CCR4-NOT transcription complex subunit 7EC 3.1.13.4; BTG1-binding factor 1; CCR4-associated factor 1; CAF-1; Caf1aHomo sapiens (human)
CCR4-NOT transcription complex subunit 9Cell differentiation protein RQCD1 homolog; Rcd-1Homo sapiens (human)
CCR4-NOT transcription complex subunit 10Homo sapiens (human)
Eukaryotic translation initiation factor 4BeIF-4BHomo sapiens (human)
Lysine-specific demethylase 6AEC 1.14.11.68; Histone demethylase UTX; Ubiquitously-transcribed TPR protein on the X chromosome; Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein; [histone H3]-trimethyl-L-lysine(27) demethylase 6AHomo sapiens (human)
E3 ubiquitin-protein ligase UHRF1EC 2.3.2.27; Inverted CCAAT box-binding protein of 90 kDa; Nuclear protein 95; Nuclear zinc finger protein Np95; HuNp95; hNp95; RING finger protein 106; RING-type E3 ubiquitin transferase UHRF1; Transcription factor ICBP90; Ubiquitin-like PHD and RING finHomo sapiens (human)
Endoribonuclease DicerEC 3.1.26.3; Helicase with RNase motif; Helicase MOIHomo sapiens (human)
Protein argonaute-2Argonaute2; hAgo2; EC 3.1.26.n2; Argonaute RISC catalytic component 2; Eukaryotic translation initiation factor 2C 2; eIF-2C 2; eIF2C 2; PAZ Piwi domain protein; PPD; Protein slicerHomo sapiens (human)
Lysine-specific demethylase 4EEC 1.14.11.66; KDM4D-like protein; Lysine-specific demethylase 4D-like; [histone H3]-trimethyl-L-lysine(9) demethylase 4EHomo sapiens (human)
Lysine-specific demethylase 6BEC 1.14.11.68; JmjC domain-containing protein 3; Jumonji domain-containing protein 3; Lysine demethylase 6B; [histone H3]-trimethyl-L-lysine(27) demethylase 6BHomo sapiens (human)
Histone H4Homo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Lysine-specific demethylase 5AEC 1.14.11.67; Histone demethylase JARID1A; Jumonji/ARID domain-containing protein 1A; Retinoblastoma-binding protein 2; RBBP-2; [histone H3]-trimethyl-L-lysine(4) demethylase 5AHomo sapiens (human)
CCR4-NOT transcription complex subunit 3CCR4-associated factor 3; Leukocyte receptor cluster member 2Homo sapiens (human)
182 kDa tankyrase-1-binding proteinHomo sapiens (human)
CCR4-NOT transcription complex subunit 11Homo sapiens (human)
Polyadenylate-binding protein 2PABP-2; Poly(A)-binding protein 2; Nuclear poly(A)-binding protein 1; Poly(A)-binding protein II; PABII; Polyadenylate-binding nuclear protein 1Homo sapiens (human)
Histone H1.8Histone H1oo; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1Homo sapiens (human)
CCR4-NOT transcription complex subunit 4EC 2.3.2.27; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; Potential transcriptional repressor NOT4Hp; RING-type E3 ubiquitin transferase CNOT4Homo sapiens (human)
CCR4-NOT transcription complex subunit 6-likeEC 3.1.13.4; Carbon catabolite repressor protein 4 homolog BHomo sapiens (human)
CCR4-NOT transcription complex subunit 2CCR4-associated factor 2Homo sapiens (human)
Developmental pluripotency-associated protein 4Homo sapiens (human)
Polyadenylate-binding protein 1PABP-1; Poly(A)-binding protein 1Homo sapiens (human)
Histone H2AXH2a/x; Histone H2A.XHomo sapiens (human)
Protein HIRATUP1-like enhancer of split protein 1Homo sapiens (human)
Histone H3.3Homo sapiens (human)
Developmental pluripotency-associated protein 2Pluripotent embryonic stem cell-related gene 1 proteinHomo sapiens (human)
Polyadenylate-binding protein-interacting protein 1PABP-interacting protein 1; PAIP-1; Poly(A)-binding protein-interacting protein 1Homo sapiens (human)

Compounds (15)

CompoundDescription
hydronium ion
Succinate
Ammonium
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Uridine TriphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
formaldehydeA highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
alpha-Ketoglutarate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)