Page last updated: 2024-10-06

Lysine Biosynthesis

Proteins (19)

ProteinSynonymsTaxonomy
4-hydroxy-tetrahydrodipicolinate synthaseHTPA synthase; EC 4.3.3.7Escherichia coli K-12
Acetylornithine/succinyldiaminopimelate aminotransferaseACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17Escherichia coli K-12
Lysine-sensitive aspartokinase 3EC 2.7.2.4; Aspartate kinase III; AKIII; Lysine-sensitive aspartokinase IIIEscherichia coli K-12
4-hydroxy-tetrahydrodipicolinate reductaseHTPA reductase; EC 1.17.1.8Escherichia coli K-12
Diaminopimelate decarboxylaseDAP decarboxylase; DAPDC; EC 4.1.1.20Escherichia coli K-12
Diaminopimelate epimeraseDAP epimerase; EC 5.1.1.7; PLP-independent amino acid racemaseEscherichia coli K-12
Anaerobic C4-dicarboxylate transporter DcuBEscherichia coli O157:H7
Anaerobic C4-dicarboxylate transporter DcuCEscherichia coli O157:H7
Aerobic C4-dicarboxylate transport proteinEscherichia coli K-12
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferaseEC 2.3.1.117; Succinyl-CoA: tetrahydrodipicolinate N-succinyltransferase; Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylaseEscherichia coli K-12
Aspartate-semialdehyde dehydrogenaseASA dehydrogenase; ASADH; EC 1.2.1.11; Aspartate-beta-semialdehyde dehydrogenaseEscherichia coli K-12
Glutamate/aspartate import ATP-binding protein GltLEC 7.4.2.1Escherichia coli K-12
Anaerobic C4-dicarboxylate transporter DcuAEscherichia coli K-12
Succinyl-diaminopimelate desuccinylaseSDAP desuccinylase; EC 3.5.1.18; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolaseEscherichia coli K-12
Glutamate/aspartate import permease protein GltJEscherichia coli K-12
Glutamate/aspartate import permease protein GltKEscherichia coli K-12
C4-dicarboxylic acid transporter DauADicarboxylic acid uptake system AEscherichia coli K-12
Proton/glutamate-aspartate symporterGlutamate-aspartate carrier protein; Proton-glutamate-aspartate transport proteinEscherichia coli K-12
Glutamate/aspartate import solute-binding proteinEscherichia coli K-12

Compounds (14)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Orthophosphate
succinic acidA water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
lysineAn essential amino acid. It is often added to animal feed.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
alpha-ketoglutaric acid
aspartic semialdehydeRN given refers to cpd without isomeric designation
creolinfrom refined coal tar oils